DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ilk and AT2G31800

DIOPT Version :9

Sequence 1:	NP_525001.2	Gene:	Ilk / 53573	FlyBaseID:	FBgn0028427	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_180739.2	Gene:	AT2G31800 / 817737	AraportID:	AT2G31800	Length:	476	Species:	Arabidopsis thaliana

Alignment Length:	437	Identity:	114/437 - (26%)
Similarity:	186/437 - (42%)	Gaps:	86/437 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 LHWVAKEGHAKLVETLLQRGSRVNATNMGDDIPLHLAAAHGHRDVVQMLIKERSDVNAVNEHGNT 102
            |.:||..|..:.|:.||..|..||:.::.....||:||..||.|||::|:..:::::|.:..|:|
plant    79 LLFVACRGDVEGVQDLLDEGIDVNSIDLDGRTALHIAACEGHVDVVKLLLTRKANIDARDRWGST 143

  Fly   103 PLHYACFWGYDMICEDLLNA-GAQVGIANKDGHTPLEKAKPSLAKRLQDLVEKSGREVKVISFKE 166
            ....|.::| :|...::|.| ||:|   .|...||:..|.|              |||.......
plant   144 AAADAKYYG-NMDVFNILKARGAKV---PKTKRTPMVVANP--------------REVPEYELNP 190

  Fly   167 QSWQGLKTRSRDATLSRFKGISMGDLDLHTKLSVTPSGETWRGRWQKNDVVAKILAVRQCTPRIS 231
            |.   |:.|..|       |||.|...:              .:|....|..|||     ...:.
plant   191 QE---LQVRKAD-------GISKGIYQV--------------AKWNGTKVSVKIL-----DKDLY 226

  Fly   232 RD------FNEE---FPKLRIFSHPNILPIIGACNSPPNLVTISQFMPRSSLFSLLH--GATGVV 285
            :|      |..|   |.|:|   |||::..:||......::.:|::.|:..|.|.|.  |.
plant   227 KDSDTINAFKHELTLFEKVR---HPNVVQFVGAVTQNVPMMIVSEYHPKGDLGSYLQKKGR---- 284

  Fly   286 VDTSQAVSFALDVARGMAFLHSLERIIPTYH--LNSHHVMIDD---------DLTARINMGDAKF 339
            :..::.:.||||:||||.:||.. :..|..|  |...::|:|.         .|.:...:...|.
plant   285 LSPAKVLRFALDIARGMNYLHEC-KPEPVIHCDLKPKNIMLDSGGHLKVAGFGLISFAKLSSDKS 348

  Fly   340 SFQEKGRIYQPA--WMSPETLQRKQADRNWEACDMWSFAILIWELTTREVPFAEWSPMECGMKIA 402
            .....|....|:  .|:||..:.:..||   :.|.:||.::::|:.....||....|.|....:.
plant   349 KILNHGAHIDPSNYCMAPEVYKDEIFDR---SVDSYSFGVVLYEMIEGVQPFHPKPPEEAVKLMC 410

  Fly   403 LEGLRVKIPPGTST---HMAKLISICMNEDPGKRPKFDMVVPILEKM 446
            |||.|......:.:   .|.:||..|.:.:...||.|..::..|:|:
plant   411 LEGRRPSFKAKSKSCPQEMRELIEECWDTETFVRPTFSEIIVRLDKI 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ilk	NP_525001.2	ANK	28..140	CDD:238125	34/102 (33%)
		ANK repeat	33..64	CDD:293786	10/25 (40%)
		Ank_2	38..130	CDD:289560	31/92 (34%)
		ANK repeat	66..97	CDD:293786	11/30 (37%)
		ANK repeat	99..130	CDD:293786	10/31 (32%)
		PK_ILK	196..446	CDD:270959	66/276 (24%)
		STYKc	204..443	CDD:214568	65/265 (25%)
AT2G31800	NP_180739.2	ANK	80..178	CDD:238125	33/101 (33%)
		Ank_2	80..167	CDD:289560	29/87 (33%)
		ANK repeat	107..138	CDD:293786	11/30 (37%)
		ANK repeat	140..165	CDD:293786	7/25 (28%)
		STKc_MAP3K-like	201..454	CDD:270901	68/282 (24%)
		TyrKc	203..454	CDD:197581	66/280 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910