Protein Alignment Ilk and Takl2

DIOPT Version :10

• Sequence 1: NP_525001.2
• Gene: Ilk / 53573
• FlyBaseID: FBgn0028427
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_651090.2
• Gene: Takl2 / 42692
• FlyBaseID: FBgn0039015
• Length: 281
• Species: Drosophila melanogaster
• Alignment Length: 261
• Identity: 61/261 - (23%)
• Similarity: 109/261 - (41%)
• Gaps: 50/261 - (19%)

  Fly   204 GETWRGRWQKNDVVAKILAVRQ-CTPRISRDFNEEFPKLRIFSHPNILPIIGACNSPPNLVTISQ 267
            |..:|..|:..::..|  .:|: |.   .:....|..:|...||.||:.:.|........:.:.:
  Fly    25 GSVYRAVWRNREIALK--RIREGCE---DKKIEREIYQLTKASHVNIVELYGTSRHEGCALLLME 84

  Fly   268 FMPRSSLFSLLHGATGVVVDTSQAVSFALDVARGMAFLHSLE-------RIIPTYHLNS------ 319
            |:...||.|.||..:......:.|.::|..:|:|:|:||.::       .|.|   ||:
  Fly    85 FVDGGSLSSFLHAKSKPSYSHAHAFNWAHQIAQGIAYLHGMQPKAVIHRDIKP---LNTLLCEKG 146

  Fly   320 -------HHVMIDDDLTARINMGDAKFSFQEKGRIYQPAWMSPETLQRKQADRNWEACDMWSFAI 377
                   ...::|...:...|.|..::.             :||.||..:.|   |.||::|:||
  Fly   147 LKLKICDFGTVVDLSQSISCNAGTCRYK-------------APEVLQGNKPD---EKCDVYSWAI 195

  Fly   378 LIWELTTREVPFAEWSPM-ECGMKIALEGLRVK---IPPGTSTHMAKLISICMNEDPGKRPKFDM 438
            ..||:.:|:.||.:::.: |..|.|. ||.|..   |..|....:..|:....:.|..||...::
  Fly   196 TFWEILSRKEPFEQYNTLFELYMAIN-EGERPDLSCIMSGCPADIVALLYASWDPDISKRFSMEL 259

  Fly   439 V 439
            :
  Fly   260 I 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ilk	NP_525001.2	ANKYR	<1..162	CDD:440430
		ANK repeat	33..64	CDD:293786
		ANK repeat	66..97	CDD:293786
		ANK repeat	99..130	CDD:293786
		PK_ILK	196..446	CDD:270959	61/261 (23%)
Takl2	NP_651090.2	Protein Kinases, catalytic domain	19..268	CDD:473864	61/261 (23%)