Protein Alignment Ilk and ilk

DIOPT Version :10

• Sequence 1: NP_525001.2
• Gene: Ilk / 53573
• FlyBaseID: FBgn0028427
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_956865.1
• Gene: ilk / 393543
• ZFINID: ZDB-GENE-040426-1435
• Length: 452
• Species: Danio rerio
• Alignment Length: 450
• Identity: 266/450 - (59%)
• Similarity: 344/450 - (76%)
• Gaps: 3/450 - (0%)

  Fly     1 MEDIFHWCREGNSIQVRLWLDETEHDNNLGDDHGFSPLHWVAKEGHAKLVETLLQRGSRVNATNM 65
            |:|||..|||||::.||||||.||:|.|.|||||||||||..:||.:.:|:.|:.||:|:|..|.
Zfish     1 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSGVVDMLIMRGARINVMNR 65

  Fly    66 GDDIPLHLAAAHGHRDVVQMLIKERSDVNAVNEHGNTPLHYACFWGYDMICEDLLNAGAQVGIAN 130
            |||.||||||:|||||::..||:.::|.||.||||||||||||||.:|.:.|||::.||||.|.|
Zfish    66 GDDTPLHLAASHGHRDILAKLIQCKADTNAANEHGNTPLHYACFWAHDQVAEDLVSNGAQVSICN 130

  Fly   131 KDGHTPLEKAKPSLAKRLQDLVEKSGREVKVISFKEQSWQG-LKTRSRDATLSRFKGISMGDLDL 194
            |.|.||::||||.||..|:||.||.|:.:..:.:|:..|:| .:||.|:.||::..||....|::
Zfish   131 KYGETPMDKAKPPLAANLKDLAEKQGQSLSKVPYKDNFWKGTTRTRPRNGTLNKQAGIDYKQLNM 195

  Fly   195 HTKLSVTPSGETWRGRWQKNDVVAKILAVRQCTPRISRDFNEEFPKLRIFSHPNILPIIGACNSP 259
            ..|::...|||.|:||||..::|.|:|.||:.|.|.|||||||:||||||||||:||::|||.||
Zfish   196 LNKINENHSGELWKGRWQGTEIVVKMLHVREWTTRKSRDFNEEYPKLRIFSHPNVLPVLGACQSP 260

  Fly   260 --PNLVTISQFMPRSSLFSLLHGATGVVVDTSQAVSFALDVARGMAFLHSLERIIPTYHLNSHHV 322
              |:.:.|:..||..||::|||..|.:|||.:|||.||||:|.||||||:||.:||.::|||..|
Zfish   261 PAPHPIIITHSMPYGSLYNLLHEGTNLVVDQNQAVKFALDIACGMAFLHTLEPMIPRHYLNSKSV 325

  Fly   323 MIDDDLTARINMGDAKFSFQEKGRIYQPAWMSPETLQRKQADRNWEACDMWSFAILIWELTTREV 387
            |||:|:||||:|.|.|.|||..||:|.|||::||.||:|..:.|..:.||||:|:|:|||.:|||
Zfish   326 MIDEDMTARISMADVKLSFQCPGRMYSPAWVAPEALQKKPEEINRRSADMWSYAVLLWELVSREV 390

  Fly   388 PFAEWSPMECGMKIALEGLRVKIPPGTSTHMAKLISICMNEDPGKRPKFDMVVPILEKMR 447
            |||:.|.||.|||:||||||..||||.|.|:.||:.|||||||.|||||||:|||||||:
Zfish   391 PFADLSNMEIGMKVALEGLRPTIPPGISPHICKLMKICMNEDPAKRPKFDMIVPILEKMQ 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ilk	NP_525001.2	ANKYR	<1..162	CDD:440430	98/160 (61%)
		ANK repeat	33..64	CDD:293786	16/30 (53%)
		ANK repeat	66..97	CDD:293786	19/30 (63%)
		ANK repeat	99..130	CDD:293786	21/30 (70%)
		PK_ILK	196..446	CDD:270959	155/251 (62%)
ilk	NP_956865.1	ANKYR	<8..203	CDD:440430	106/194 (55%)
		ANK repeat	33..64	CDD:293786	16/30 (53%)
		ANK repeat	66..97	CDD:293786	19/30 (63%)
		ANK repeat	99..130	CDD:293786	21/30 (70%)
		PK_ILK	197..449	CDD:270959	155/251 (62%)