Protein Alignment Ilk and Ilk

DIOPT Version :10

• Sequence 1: NP_525001.2
• Gene: Ilk / 53573
• FlyBaseID: FBgn0028427
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: XP_316598.2
• Gene: Ilk / 1277157
• VectorBaseID: AGAMI1_002725
• Length: 448
• Species: Anopheles gambiae
• Alignment Length: 448
• Identity: 345/448 - (77%)
• Similarity: 399/448 - (89%)
• Gaps: 0/448 - (0%)

  Fly     1 MEDIFHWCREGNSIQVRLWLDETEHDNNLGDDHGFSPLHWVAKEGHAKLVETLLQRGSRVNATNM 65
            |||||||||||||||||||||:||||.|||||||||||||.|||||:||||.||.||:|||||||
Mosquito     1 MEDIFHWCREGNSIQVRLWLDDTEHDMNLGDDHGFSPLHWCAKEGHSKLVEMLLHRGARVNATNM 65

  Fly    66 GDDIPLHLAAAHGHRDVVQMLIKERSDVNAVNEHGNTPLHYACFWGYDMICEDLLNAGAQVGIAN 130
            |||||||||:||||.|:|||||:.||||||.||||||||||||||||..|.|:|:|.||.:.:||
Mosquito    66 GDDIPLHLASAHGHYDIVQMLIRHRSDVNAANEHGNTPLHYACFWGYQAIAEELVNNGALISLAN 130

  Fly   131 KDGHTPLEKAKPSLAKRLQDLVEKSGREVKVISFKEQSWQGLKTRSRDATLSRFKGISMGDLDLH 195
            |||.|||:|||..||.||.:|..:||:|:|.||||:|||.|:|||||||||||||||::.:|.||
Mosquito   131 KDGDTPLDKAKALLATRLHNLAVESGQELKKISFKDQSWSGMKTRSRDATLSRFKGINIQELTLH 195

  Fly   196 TKLSVTPSGETWRGRWQKNDVVAKILAVRQCTPRISRDFNEEFPKLRIFSHPNILPIIGACNSPP 260
            .|:::||.|||||||||.|:::|||||:|:||.|::||||||||||||||||||||::||||:|.
Mosquito   196 NKVAITPGGETWRGRWQNNEIIAKILAIRECTARVARDFNEEFPKLRIFSHPNILPVLGACNAPS 260

  Fly   261 NLVTISQFMPRSSLFSLLHGATGVVVDTSQAVSFALDVARGMAFLHSLERIIPTYHLNSHHVMID 325
            ||:.|||:|||.||:.||||..|:||||:|||.||||:|||||:|||||||||.|||||.|||||
Mosquito   261 NLIVISQYMPRGSLYDLLHGTAGIVVDTAQAVRFALDIARGMAYLHSLERIIPEYHLNSFHVMID 325

  Fly   326 DDLTARINMGDAKFSFQEKGRIYQPAWMSPETLQRKQADRNWEACDMWSFAILIWELTTREVPFA 390
            |||||||||.||||||||:||:|||||||||.||:|:.:|||||||||||||.||||.|||:|||
Mosquito   326 DDLTARINMADAKFSFQERGRVYQPAWMSPEMLQKKRTERNWEACDMWSFAICIWELATREIPFA 390

  Fly   391 EWSPMECGMKIALEGLRVKIPPGTSTHMAKLISICMNEDPGKRPKFDMVVPILEKMRR 448
            :.:|||.||:||.|||||.||||||.|:||||.|||||||||||.|||::|||:||:|
Mosquito   391 DLTPMEAGMRIATEGLRVTIPPGTSPHLAKLIKICMNEDPGKRPTFDMIIPILDKMKR 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ilk	NP_525001.2	ANKYR	<1..162	CDD:440430	125/160 (78%)
		ANK repeat	33..64	CDD:293786	25/30 (83%)
		ANK repeat	66..97	CDD:293786	25/30 (83%)
		ANK repeat	99..130	CDD:293786	20/30 (67%)
		PK_ILK	196..446	CDD:270959	191/249 (77%)
Ilk	XP_316598.2	ANKYR	<1..156	CDD:440430	121/154 (79%)
		ANK repeat	33..64	CDD:293786	25/30 (83%)
		ANK repeat	66..97	CDD:293786	25/30 (83%)
		ANK repeat	99..130	CDD:293786	20/30 (67%)
		Protein Kinases, catalytic domain	196..446	CDD:473864	191/249 (77%)