DRSC/TRiP Functional Genomics Resources

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Protein Alignment pins and Ttc24

DIOPT Version :9

Sequence 1:NP_524999.2 Gene:pins / 53569 FlyBaseID:FBgn0040080 Length:658 Species:Drosophila melanogaster
Sequence 2:NP_766114.1 Gene:Ttc24 / 214191 MGIID:2443841 Length:334 Species:Mus musculus


Alignment Length:312 Identity:81/312 - (25%)
Similarity:139/312 - (44%) Gaps:43/312 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   213 DRGAQGRACGNLGNTYYLLGDFQAAIEHHQERLRIAREFGDRAAERRANSNLGNSHIFLGQFEDA 277
            |:|..|....:||..|:.|..|..|:|...:.|.:.|:..::|.   ...|||.:|..||.:.:|
Mouse    30 DQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQAT---VLQNLGMTHNVLGNYWEA 91

  Fly   278 AEHYKRTLALAVELGEREVEAQSCYSLGNTYTLLHEFNTAIEYHNRHLAIAQELGDRIGEARACW 342
            .|.:::..:|...:|:|..:.:|...|..:.:.|.:...|.:.:...|..||:.||..|:.:||.
Mouse    92 QEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACE 156

  Fly   343 SLGNAHSAIGGHERALKYAEQHL------------QLAKELHDPVGESTARVNISDLRKLLGMP- 394
            .||.|.:.:|.|::||||.::.|            :|..:|.|.:....|:..|:..|.|...| 
Mouse   157 GLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPG 221

  Fly   395 ---DSEPSPTEEEARSTASDHSAS---GNQSDGSENSQ--------GRMVRVRRQSMEQLDLIK- 444
               .|..:.|....:|:|.|...|   |..|:|....:        ..::..:||:.....|.. 
Mouse   222 KLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSG 286

  Fly   445 -ITPDGKR----MQEEKLR-AQATRKAKDDDFFEMLSRS-QSKRMDDQRCSI 489
             .:|.|:.    :..:||| ::::..||     |.|.|: |..|:....|||
Mouse   287 GPSPSGEEYPFIIAPKKLRVSRSSTWAK-----EALGRNFQRTRIQSGLCSI 333

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pinsNP_524999.2 TPR_12 78..153 CDD:290160
TPR 83..114 CDD:197478
TPR repeat 83..109 CDD:276809
TPR repeat 120..150 CDD:276809
TPR_12 121..203 CDD:290160
TPR_12 162..250 CDD:290160 11/36 (31%)
TPR repeat 162..199 CDD:276809
TPR 219..251 CDD:197478 9/31 (29%)
TPR repeat 219..246 CDD:276809 7/26 (27%)
TPR repeat 251..291 CDD:276809 10/39 (26%)
TPR_12 259..330 CDD:290160 17/70 (24%)
TPR repeat 296..326 CDD:276809 4/29 (14%)
TPR_12 298..370 CDD:290160 23/83 (28%)
TPR 298..330 CDD:197478 6/31 (19%)
TPR repeat 338..366 CDD:276809 12/39 (31%)
GoLoco 468..488 CDD:280368 5/20 (25%)
GoLoco 552..573 CDD:280368
GoLoco 613..633 CDD:280368
Ttc24NP_766114.1 TPR 1 35..68 10/32 (31%)
TPR repeat 38..66 CDD:276809 8/27 (30%)
TPR_12 68..144 CDD:290160 18/78 (23%)
TPR 2 72..105 10/35 (29%)
TPR repeat 72..100 CDD:276809 9/30 (30%)
TPR repeat 111..141 CDD:276809 5/29 (17%)
TPR 3 112..145 7/32 (22%)
TPR_12 113..183 CDD:290160 22/69 (32%)
TPR 4 152..185 12/32 (38%)
TPR_1 152..184 CDD:278916 12/31 (39%)
TPR repeat 152..180 CDD:276809 11/27 (41%)
TPR_12 158..214 CDD:290160 15/55 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 220..258 10/37 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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