Protein Alignment larp and Larp4B

DIOPT Version :9

• Sequence 1: NP_001247347.1
• Gene: larp / 53567
• FlyBaseID: FBgn0261618
• Length: 1673
• Species: Drosophila melanogaster
• Sequence 2: NP_647793.1
• Gene: Larp4B / 38399
• FlyBaseID: FBgn0035424
• Length: 1531
• Species: Drosophila melanogaster
• Alignment Length: 1374
• Identity: 256/1374 - (18%)
• Similarity: 414/1374 - (30%)
• Gaps: 499/1374 - (36%)

  Fly   487 TNSQATTAPVASTSHDAKAQRDAEPAA---------NSAAGTTGTAAGPALTKKIPKHKWRPLPI 542
            ||....||.:|:....|..|..|.|||         .:||.....|..||:...:     ...|:
  Fly    24 TNVPVETAMLATNLFGATTQIAASPAAAAAAHIPLITAAAAAAAAAGAPAVAPPV-----AVAPV 83

  Fly   543 DLAKSSRPKPIGGRPNRRFSDDIADQRRPPRVYHDRQPGAGGAGV--------ESRHPHAGRH-P 598
            ..|.:::...:..:..::.....|.......|.|.:|.......:        :.:.||..:| .
  Fly    84 ATASAAQAAVVPAQQQQQAHPHQAQILAHTHVAHQQQQQQQQQTIQQHLHQQQQQQSPHPAQHLT 148

  Fly   599 YGSRPATATSERVDSWRSSSSTTTAAFDEQRSGAAGGAGAAGTGVGSATRGPRRYRTPYRGGRQG 663
            ||.:||.:                       ...|||:|...                  ||..|
  Fly   149 YGHQPALS-----------------------QATAGGSGTIS------------------GGAVG 172

  Fly   664 RGGFSRQGPGRPTYRIPRHLLA---SGEYANY--------------------------------- 692
            ..|...:|.....|.|....|.   .|....|
  Fly   173 PSGVVVEGQDTNEYAIMNGALGQTQDGTVVCYTTDALNNTNLVALDPQPHQIVVPVQVPVQVPVP 237

  Fly   693 --LPADAAGADSQSSYVLMGTHYFGNVPAAYIELDANSIKEAIKKQVEYYFSVDNLTGDFFLRRK 755
              |||:.:....|.|:...|    |..|  .|.||  .:|:.:..|:|||||.:||..|.:|..:
  Fly   238 VQLPANGSADPQQGSHNAAG----GEEP--NIPLD--KLKQMLATQLEYYFSRENLANDTYLLSQ 294

  Fly   756 MDPEGYIPVTLIASFHRVLALTTDVAVIVNAIKESDKLELFE-GYKVR---------TKTTPTTW 810
            ||.:.|:|:..:|.|:.|..||.|:.:|...::||..:::.: |.:||         .:......
  Fly   295 MDSDQYVPIYTVARFNLVRKLTNDINLITEVLRESPNVQVDDKGLRVRPNRKRCIIILREISNNT 359

  Fly   811 PITEVPEV--NEGEPKAIG-----------TLEQEQLEQNDGQEK---LEEQTEADSPPPILTSA 859
            |:.:|..:  ||..|:.|.           |.|.::    |.|:.   |.|:.:.....||:...
  Fly   360 PLDDVKALFSNESCPRPISCEFAANNSWYITFESDE----DAQKAYKYLREEVKEFQGKPIMARI 420

  Fly   860 MATKPLNSIPPPPMPRNPQNLVPKMLQDKQQSRSSTIAALNSVNAISALTQQVEGGAAELAGHL- 923
            .....:|.|...|               |...|.::....|..:...|....|...||:...:|
  Fly   421 KPKSFINRIQAVP---------------KNGYRLTSPPTANVFDPAGAGGATVSYAAAQQPRYLY 470

  Fly   924 -SGLAESVKPKSTS------TPDKRNAASAGNGA-----GSAAALVAEPEGIWKEVKRRSKTNAI 976
             :|.|.:. |.|..      .|..:|....|..|     |:.||..|..:..::.......||.:
  Fly   471 TNGAAIAA-PASVQYSNPVLIPIPQNQFYPGLVAGPWPPGTVAATTAHGQNFYELGGNIFTTNPL 534

  Fly   977 KENATTPPQ-------QQQPPLSQTL----------NNNNDNVKTNNTSSKSKSSSNNAPSNASS 1024
                  |||       |..||.||.:          .|||.....||.     ..:|:.|
  Fly   535 ------PPQPVTAGFAQAPPPTSQAMVTPKPQGGGRYNNNHRGNPNNV-----GGANSGP----- 583

  Fly  1025 SATVCVTTNNASSATKATTKTTTTSTATTTTNNNIKSGNAAYSKTHSKSSSKTAAPPSAQCHAEK 1089
                     .|.|.:|....|.:.|        :|:.||....:.       ||..|........
  Fly   584 ---------RAESRSKPPRSTPSAS--------HIQGGNIMPIQI-------TAPIPGGMVSVVP 624

  Fly  1090 EELDFQFDEELMDPLPPGTGRINNFTENFSDDDESDYEFADRDINKLLIVAQVGRAPKHEGYDRT 1154
            ..:       :.|||.|                      |........::.|:.:.|......:.
  Fly   625 TNI-------VQDPLQP----------------------APLQQQPQQVIQQIQQQPSSSAQQQQ 660

  Fly  1155 ADFTSRTKITQDLENIINDGLVNYEEDLWTTTN--VVADYKTVNVISQADFEKLAGGRNKSVLPP 1217
            |       .|..:.|              ||.:  :.:::|              ||..|
  Fly   661 A-------ATVQMNN--------------TTRHYPIKSNWK--------------GGMQK----- 685

  Fly  1218 QVVPPPPPFEEDLDETLVGDTTLNSTLNNTLKSRRARFYAAPNSHSIDPRTPRKRKLRHTANPPV 1282
                       :||::..|....:......:::..|      :||.:..:...:.:
  Fly   686 -----------NLDKSYSGGVATHHHYTTQVQALPA------HSHHLQAQQQLQGQ--------- 724

  Fly  1283 EAHVGWLLDTVEHRPRTTSMGSSAGTSPTASSYGSFGSSVPQSLPVFQHPSHALLKENNFTQQAY 1347
                     |.:...:..|  |||.::|..    ::.::.|......||..|.::::   ||...
  Fly   725 ---------TQQQHYQLAS--SSAASAPQV----TYVTTAPAPQQPGQHQHHLVVQQ---TQPQQ 771

  Fly  1348 HKYHSRCLKERRRLGYGQSQEMNTLYRFWSFFLRENFNKSMYNEFRSLALEDAGNGFRYGLECLF 1412
            .:...:.:.:::::   |.||                            |::||:|..:.
  Fly   772 QQQQQQVVLQQQQV---QVQE----------------------------LQEAGDGVEHS----- 800

  Fly  1413 RFFSYGLEKKFRPNIYQDFQDETIA-------------------DYETGQLYGLEKFWAFLKYYK 1458
               |:.:::..|.:........::|                   |.|.|           :.|..
  Fly   801 ---SHAMQQVNRSSNMSASSSSSLATSMSKEPLQWQNRPRRRRRDEEGG-----------INYSP 851

  Fly  1459 NGEKLEVQPKLAEYLKSFKNIEDFRVVEPEINEMLQGVGSLNPGRQLNRHRSVSESDGTAVIAAG 1523
            .|       ::..|..|..|      ..|:.:.|....||        ..:|...:||......|
  Fly   852 GG-------RVGLYGSSPSN------PHPQQHLMSSSTGS--------NVQSAGGTDGGGASHRG 895

  Fly  1524 GRRLN--TTI------TNRSDYVGRLLQQQHQQQ-------------------QQQQHH----QY 1557
            |.|.:  .||      .:|.:|.|......:..|                   ||||||    ..
  Fly   896 GERQSHYNTIHDVPPPQHRGNYKGNNYNPHYHAQHSSMASGSHHHHHHNALSSQQQQHHLTTGTG 960

  Fly  1558 QQGYG-GYNQQQNRRRTGS--FGSTTVRIRSGSLGNKPQVANRNQGSQHELRRGGSNS------- 1612
            |||.| .|:...:....||  ..|..:.:.||..|.    .....||......||||.
  Fly   961 QQGSGHHYHHHHHHNSIGSNVGNSGGLGVSSGGSGG----GGSGGGSGSNSLSGGSNERGIHHSS 1021

  Fly  1613 -GLAPH---------KRQQQQKPKPGAGSQ-------------TGSTRATTSAAATATTAASAAT 1654
             |...|         ::||||:.:|.|..|             ..:|.||......||..||...
  Fly  1022 LGYQGHQHQHQQQQQQQQQQQQQQPAAPVQPPQFDLEDAAFPPLPATSATAPHTPQATGGASLHN 1086

  Fly  1655 STAATPAVT 1663
            ||.::.:.|
  Fly  1087 STTSSSSST 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
larp	NP_001247347.1	LARP_1_2	730..803	CDD:153403	27/82 (33%)
		DM15	1341..1382	CDD:128927	5/40 (13%)
		DM15	1383..1421	CDD:128927	5/37 (14%)
Larp4B	NP_647793.1	LARP_4_5_like	269..343	CDD:153400	26/73 (36%)
		RRM_LARP4_5_like	348..423	CDD:240876	14/78 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456179
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9176
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22792
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940