Protein Alignment larp and larp1

DIOPT Version :10

• Sequence 1: NP_733244.5
• Gene: larp / 53567
• FlyBaseID: FBgn0261618
• Length: 1673
• Species: Drosophila melanogaster
• Sequence 2: XP_021324942.1
• Gene: larp1 / 327175
• ZFINID: ZDB-GENE-030131-5386
• Length: 993
• Species: Danio rerio
• Alignment Length: 1327
• Identity: 404/1327 - (30%)
• Similarity: 569/1327 - (42%)
• Gaps: 418/1327 - (31%)

  Fly   283 TSPLDKRVLQPKAQQQQQQTKQTASQNNNAQNTASNKKTQQQQQPQQGATTTTQTTTAAAAAATA 347
            |.|.:..:|||  ::.|.:..:...|..:..::.|....|::|
Zfish     7 TLPPNNPLLQP--EEPQHKDGEYPLQERHTADSGSPGAGQEEQ---------------------- 47

  Fly   348 AAAATAATTSAAAATSSAAAVPAATTETATTTTVD---ASQADALAKVVVKDKKKVNQ--KASDF 407
                      ||....|.|.:|.....|...:.|:   |::.....|||.....::.:  |..||
Zfish    48 ----------AAGREISEAPLPKVNPWTKKMSGVNGQPAAEHSGPTKVVKAGNSRLRRGGKVGDF 102

  Fly   408 SNVGDWPTLIGGTSGSGKATSNE--------PKRNPTKKQQSAKTAAAVAASSNTTSSEVATESN 464
            .:..:|||       .|:..:.|        .||.|..|::|.::...:.:.|:.:..:
Zfish   103 GDTNNWPT-------PGEIATKEVQVLKKPTVKREPKGKRESEESKENLKSKSDDSGED------ 154

  Fly   465 VAGTTSSSNSNPSSSTTTTNTTTNSQATTAPVASTSHDAKAQRDAEPAANSAAGTTGTAAGPALT 529
                              .||...||       .:||..:..
Zfish   155 ------------------KNTDEESQ-------RSSHRRRGN----------------------- 171

  Fly   530 KKIPKHKWRPLPIDLAKSSRPKPIGGRPNRRFSDDIADQRRPPRVYHDRQPGAGGAGVESRHPHA 594
                |.:|.||.|:: |:..|:......|         ..||    :|...|.          |:
Zfish   172 ----KQRWVPLMIEV-KAEGPRERSASRN---------NTRP----YDAHRGT----------HS 208

  Fly   595 GRHPYGSRPATATSERVDSWRSSSSTTTAAFDEQRSGAAGGAGAAGTGVGSATRGPRRYRTPYRG 659
            .|:.....|    |||.:......      .||..|..:.||                   |||.
Zfish   209 SRNGLRDWP----SERFEQELKDD------HDEVSSVKSDGA-------------------PYRA 244

  Fly   660 GRQGRGGFSRQGPGRPTYRIPRHLLASGEYANYLPADAAGADS--QSSYVLMGTHYFGNVPAAYI 722
            |.:|||....:|.||...|        |.|..|....:.|.|.  ...:....|:|:.|:.:|.:
Zfish   245 GARGRGRGRGRGRGRGRGR--------GHYDYYSYKGSEGKDGAYAQKFGNSMTYYYDNMSSAEL 301

  Fly   723 -ELDANSIKEAIKKQVEYYFSVDNLTGDFFLRRKMDPEGYIPVTLIASFHRVLALTTDVAVIVNA 786
             .:|.:.:|:.||:|:|||||||||..|||||||||..|::||:||||||||.||||||::|:.|
Zfish   302 YSVDQDLLKDYIKRQIEYYFSVDNLERDFFLRRKMDEGGFLPVSLIASFHRVQALTTDVSLILQA 366

  Fly   787 IKESDKLELFEGYKVRTKTTPTTWPITEVPEVNEGEPKAIGTLEQEQLEQNDGQEKLEEQTEADS 851
            :|:|..:::.: .|:|.|..|..||:.::                          .|.:|.:.|.
Zfish   367 LKDSKVVDIID-MKMRCKEEPQKWPLPDL--------------------------CLPDQAQTDF 404

  Fly   852 PPPILTSAMATKPLNSIPPPPMPRNPQNLVPKMLQDKQQSRSSTIAALNSVNAISALTQQVEGGA 916
            ...|.......:.|.:.|.|
Zfish   405 AQFIHCPEFIPRHLPASPSP--------------------------------------------- 424

  Fly   917 AELAGHLSGLAESVKPKSTSTPDKRNAASAGNGAGSAAALVAEPEGIWKEVKRRSKTNAIKENAT 981
                   :|...|..|:| |||.:...:......|.:|:|.......|.|||:|.:
Zfish   425 -------AGTPRSGTPRS-STPHQELCSLKMMPKGLSASLPDLDSECWIEVKKRPR--------- 472

  Fly   982 TPPQQQQPPLSQTLNNNNDNVKTNNTSSKSKSSSNNAPSNASSSATVCVTTNNASSATKATTKTT 1046
              |...:|        ..::|:                         ||
Zfish   473 --PSPARP--------KKEDVR-------------------------CV---------------- 486

  Fly  1047 TTSTATTTTNNNIKSGNAAYSKTHSKSSSKTAAPPSAQCHAEKEELDFQFDEEL--MDPLPPGTG 1109
                        ::.|..                 ||:...|.|||||.||||:  ||      |
Zfish   487 ------------LQMGQV-----------------SAEEQEEPEELDFMFDEEMQQMD------G 516

  Fly  1110 RINNFTENFSDDDESDYEFADRDINKLLIVAQVGRAP---KHEGYDRTADFTSRTKITQDLENII 1171
            |.|.||: :||:| ||.|..|||:||:|||.|.  .|   ||.|.|||...|||:|::.:|..||
Zfish   517 RRNTFTD-WSDED-SDCEIDDRDVNKILIVTQT--PPYLRKHPGGDRTGHHTSRSKLSSELVKII 577

  Fly  1172 NDGLVNYEEDLWTTT---------NVVADYKTVNVISQADFEKLAGGRNKSVLPPQVVPPPPPF- 1226
            ||||..||:|||..:         ..|.::|.|::||:..|:.|.  ....|.|.|.|||.||.
Zfish   578 NDGLFYYEQDLWDDSGEPEYAIIKQEVENFKKVHLISREQFDCLT--PEPPVDPNQEVPPGPPRP 640

  Fly  1227 ----------EEDLDETLVG-------DTTLNSTLNNTLKSRRA-----------------RFY- 1256
                      .|.|...|.|       ..:|.:|:.::...|.|                 |||
Zfish   641 TQSKIHTLFPTEALANKLFGAPDPSCMARSLPTTVPDSPSHRSARTPRTPRTPRLKDAQTPRFYP 705

  Fly  1257 AAPNSHSIDPRTPRKRKLRHTANPPVEAHVGWLLDTVEHRPRTTSMGSSAGTSPTASSYGSFGSS 1321
            ...:...:|.:||||||.||::|||:|.||||::|:.|||.||.|:.|:|..|...::.|:||.:
Zfish   706 VVKDGRPLDAKTPRKRKTRHSSNPPMECHVGWVMDSREHRSRTASVSSNASPSEGTAAMGNFGCT 770

  Fly  1322 VPQSLPVFQHPSHALLKENNFTQQAYHKYHSRCLKERRRLGYGQSQEMNTLYRFWSFFLRENFNK 1386
             |||||.||||||.|||||.|||..||||..|||.||:|||.|||||||||:||||||||::||:
Zfish   771 -PQSLPKFQHPSHELLKENGFTQHVYHKYRRRCLNERKRLGIGQSQEMNTLFRFWSFFLRDHFNR 834

  Fly  1387 SMYNEFRSLALEDAGNGFRYGLECLFRFFSYGLEKKFRPNIYQDFQDETIADYETGQLYGLEKFW 1451
            .||.|||.|::||...|:||||||||||:|||||:||||:|::|||:||:.|||.||||||||||
Zfish   835 KMYEEFRQLSVEDGKEGYRYGLECLFRFYSYGLERKFRPDIFKDFQEETVKDYEAGQLYGLEKFW 899

  Fly  1452 AFLKYYKNGEKLEVQPKLAEYLKSFKNIEDFRVVEPEINEMLQGVGSLNPGRQLNRH------RS 1510
            |||||.|. :.:|::|||.|:|..|:.:|||||..|..:.:.:...|...||:  ||      ||
Zfish   900 AFLKYSKT-KNMEIEPKLQEHLSKFRRLEDFRVDPPMEDGVRKRHSSSGDGRR--RHPSHPGSRS 961

  Fly  1511 VSESD-GTAVIAAGGRRLNTTITNRSD 1536
            .::|. ..:..|||..|.::...::.|
Zfish   962 QTQSQLQPSGAAAGATRDDSRAQSQRD 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
larp	NP_733244.5	LARP_1_2	730..803	CDD:153403	44/72 (61%)
		DM15	1341..1382	CDD:128927	31/40 (78%)
		DM15	1383..1421	CDD:128927	25/37 (68%)
larp1	XP_021324942.1	LARP_1	310..382	CDD:153406	44/72 (61%)
		DM15	790..830	CDD:128927	31/39 (79%)
		DM15	831..869	CDD:128927	25/37 (68%)