DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment larp and Ssb

DIOPT Version :9

Sequence 1:	NP_001247347.1	Gene:	larp / 53567	FlyBaseID:	FBgn0261618	Length:	1673	Species:	Drosophila melanogaster
Sequence 2:	NP_001103615.1	Gene:	Ssb / 20823	MGIID:	98423	Length:	415	Species:	Mus musculus

Alignment Length:	435	Identity:	98/435 - (22%)
Similarity:	152/435 - (34%)	Gaps:	103/435 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   728 SIKEAIKKQVEYYFSVDNLTGDFFLRR--KMDPEGYIPVTLIASFHRVLALTTDVAVIVNAIKES 790
            :::..|..|:||||...||..|.||:.  |:| ||::|:..:..|:|:..||||..|||.|:.:|
Mouse    12 ALEAKICHQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLETMIKFNRLNRLTTDFNVIVQALSKS 75

  Fly   791 DKLELFE--GYKVRTKTTPTTWPITEVPEVNEGEPK----------AIGTLE--QEQLEQ----- 836
             |.:|.|  ..|.:.:.:|:. |:.||.:..:.:.|          ...||:  :|.|:.
Mouse    76 -KAKLMEVSADKTKIRRSPSR-PLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQIL 138

  Fly   837 NDGQEKLEEQTEADSPPPILTSAMATKPLNSIPPPPMPRNPQNLVPKMLQD----KQQSRSSTIA 897
            |....:...:|...|...:..|..:.|....|  |.......||:....:|    |.:.|..
Mouse   139 NIQMRRTLHKTFKGSIFAVFDSIQSAKKFVEI--PGQKYKDTNLLILFKEDYFAKKNEERKQ--- 198

  Fly   898 ALNSVNAISALTQQVEG----GAAE---LAGHLSGLAESVKPKSTSTPDKRNAAS------AGNG 949
              :.|.|.....|:.||    |:.|   |.|.:..|.     |.:...|.:....      :.:|
Mouse   199 --SKVEAKLKAKQEHEGRHKPGSTETRALEGKMGCLL-----KFSGDLDDQTCREDLHFLFSNHG 256

  Fly   950 AGSAAALVAEPEGIWKEVKRRSKTNAI--KENATTPPQQQQPPLSQTLNNNNDNVKTNNTSSKSK 1012
                       |..|.:..|.:|...|  ||.|       :..|.:..|.||.|:...|.....|
Mouse   257 -----------EIKWVDFARGAKEGIILFKEKA-------KEALEKARNANNGNLLLRNKKVTWK 303

  Fly  1013 SSSNNAPSNASSSATVCVTTNNASSATKATTKTTTTSTATTTTNNNIKSGNAAYSKTHSKSSSKT 1077
            ....:|...|...    :|.:...|..|..:|       ........|..:...:....|...|.
Mouse   304 VLEGHAEKEALKK----ITDDQQESLNKWKSK-------GGHAGGRFKGSHVFTAARRFKGKGKG 357

  Fly  1078 AAPPSAQCHAEKEELDFQFDEELMDPLPPGTGRINNFTENFSDDD 1122
            ..|..|..                   |.|.|:.:.....|.|||
Mouse   358 NRPGYAGA-------------------PKGRGQFHGRRTRFDDDD 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
larp	NP_001247347.1	LARP_1_2	730..803	CDD:153403	31/76 (41%)
		DM15	1341..1382	CDD:128927
		DM15	1383..1421	CDD:128927
Ssb	NP_001103615.1	LARP_3	10..91	CDD:153397	31/80 (39%)
		RRM1_La	112..183	CDD:240737	13/72 (18%)
		RRM_3	230..333	CDD:285930	25/136 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	349..415		11/54 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900