DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kat60 and GUT1

DIOPT Version :9

Sequence 1:	NP_001262276.1	Gene:	Kat60 / 53566	FlyBaseID:	FBgn0040208	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_011831.1	Gene:	GUT1 / 856353	SGDID:	S000001024	Length:	709	Species:	Saccharomyces cerevisiae

Alignment Length:	155	Identity:	40/155 - (25%)
Similarity:	63/155 - (40%)	Gaps:	36/155 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 HLEKLTHSSALIGTNLCL-SFLATMTTTCSDRQLLRGGKQKTTTCVGMTVMAKTTFEEICENAKL 69
            |.:||     |:....|| |.|.::.|..|:| :..|.......|:|:..|.:||   |..:.:.
Yeast   156 HPQKL-----LVNVVQCLASSLLSLQTINSER-VANGLPPYKVICMGIANMRETT---ILWSRRT 211

  Fly    70 ARDMALTGNYDSACIYYEGLQGLLARQLKATADPLRKGKWSMINQQISQEHAKIKAIQRTLQDIS 134
            .:.:.   ||        |:.....|.:|...|     ||.  |..:.::   ::..|:|    .
Yeast   212 GKPIV---NY--------GIVWNDTRTIKIVRD-----KWQ--NTSVDRQ---LQLRQKT----G 251

  Fly   135 LDLQSTKFA-HKLRHQLSEESTTSK 158
            |.|.||.|: .|||..|..|...:|
Yeast   252 LPLLSTYFSCSKLRWFLDNEPLCTK 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693
		P-loop_NTPase	325..>381	CDD:304359
		AAA	358..496	CDD:214640
		AAA	362..495	CDD:278434
		Vps4_C	<570..603	CDD:286426
GUT1	NP_011831.1	NBD_sugar-kinase_HSP70_actin	46..685	CDD:418402	40/155 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900