Protein Alignment Kat60 and YTA6

DIOPT Version :10

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_015251.1
• Gene: YTA6 / 856031
• SGDID: S000005995
• Length: 754
• Species: Saccharomyces cerevisiae
• Alignment Length: 578
• Identity: 193/578 - (33%)
• Similarity: 289/578 - (50%)
• Gaps: 101/578 - (17%)

  Fly    57 KTTFEEICENAKLARDMALTGNYDSACIYYEGLQGLLARQLKATADPLRKGKWSMINQQISQEHA 121
            ||.::........:.....:|..|::.|....|. ::....:....|:||          |.|.|
Yeast   247 KTNYKSRASLDNFSSSSKSSGKIDNSLIKRRSLD-VVRTSGERVRTPVRK----------SMEAA 300

  Fly   122 KIKAIQRTLQDISLDLQSTKFAHKLRH-QLSEESTTSKDPSAWFKPDPDIWTPP------PKDPD 179
            :|        .::..|..:::.:...| ::|...:.|.:....:||     |||      .|.|.
Yeast   301 EI--------GMAAQLAWSQYQNGANHSKVSNNGSHSNELQIRYKP-----TPPLKKRYDYKKPT 352

  Fly   180 VWGPPKPPPTTQAVGRRAAPNNRRTTPATQNSRPSSTIPQSTARNGPASTRNSRN-------STS 237
            |..|....||.          ||:.:.:::|...:|.:..|.:.....|.||.:|       ..|
Yeast   353 VNRPIIKSPTL----------NRQNSKSSRNIPTNSKLKASKSNTNKVSRRNEQNLEPSSPVLVS 407

  Fly   238 ATAPSGGARTTNGRAG--GRKLSTSNTNEARDDDSTAAGNNGGAAGDGENGDPQAAQEEERKFQP 300
            |||....::....::|  .::.|.|::.::|.:|...:     ..|...|...|...|
Yeast   408 ATAVPAESKPMRSKSGTPDKESSASSSLDSRKEDILKS-----VQGVDRNACEQILNE------- 460

  Fly   301 NNHIEAELVDILERDILQKDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFKGIRRPWKGVLMV 365
                           ||..|.||.|.|||.|.:||..|:||||.|.|.||.|||:|.|.:|:|:.
Yeast   461 ---------------ILVTDEKVYWEDIAGLRNAKNSLKEAVVYPFLRPDLFKGLREPVRGMLLF 510

  Fly   366 GPPGTGKTMLAKAVATECGTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDSL 430
            |||||||||:|||||||..:|||:||:::|.|||.|||||:||.||.||:..:||.||||||||:
Yeast   511 GPPGTGKTMIAKAVATESNSTFFSVSASSLLSKYLGESEKLVRALFYMAKKLSPSIIFIDEIDSM 575

  Fly   431 CSRRGSESEHEASRRVKSELLVQMDGVGGGEEQAK--------VVMVLAATNFPWDIDEALRRRL 487
            .:.| |::|:|:|||:|:|||:|...:.....|::        .|:||.|||.||.||:|.|||.
Yeast   576 LTAR-SDNENESSRRIKTELLIQWSSLSSATAQSEDRNNTLDSRVLVLGATNLPWAIDDAARRRF 639

  Fly   488 EKRIYIPLPSDEGREALLKINLREVKVDDSVDLTY--VANELKGYSGADITNVCREASMMSMR-- 548
            .:::|||||..|.|...|| .|...:.:...||.|  :....:|:||:|:|::.:||:|..:|
Yeast   640 SRKLYIPLPDYETRLYHLK-RLMAKQKNSLQDLDYELITEMTEGFSGSDLTSLAKEAAMEPIRDL 703

  Fly   549 -RKIAGLTPEQIRQLATEEVDLPVSNKDFNEAMSRCNKSVSRADLDKYEKWMREFGSS 605
             .|:.....::||.:   |:      |||..|:....||||...|.|||:|..:|||:
Yeast   704 GDKLMFADFDKIRGI---EI------KDFQNALLTIKKSVSSESLQKYEEWSSKFGSN 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	Kp60-NTD	62..129	CDD:439297	11/66 (17%)
		PHA03291	<167..>253	CDD:223033	22/98 (22%)
		SpoVK	219..566	CDD:440232	144/368 (39%)
		RecA-like_KTNA1	327..493	CDD:410930	95/173 (55%)
		Vps4_C	<570..603	CDD:462762	13/32 (41%)
YTA6	NP_015251.1	PTZ00108	<158..412	CDD:240271	41/198 (21%)
		RecA-like_VPS4-like	473..645	CDD:410917	94/172 (55%)
		AAA_lid_3	670..714	CDD:465537	13/43 (30%)
		Vps4_C	<718..750	CDD:462762	14/40 (35%)