Protein Alignment Kat60 and RPT1

DIOPT Version :10

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_012777.1
• Gene: RPT1 / 853712
• SGDID: S000001628
• Length: 467
• Species: Saccharomyces cerevisiae
• Alignment Length: 525
• Identity: 139/525 - (26%)
• Similarity: 225/525 - (42%)
• Gaps: 114/525 - (21%)

  Fly   103 PLRKGKWSMINQQISQEH-AKIKAIQRTLQDISLDLQSTKFAHKLRHQLSEESTTSKDPSAWFKP 166
            ||.:|...::....:..: ||:|..:..|:||...::.....        :||.|...||
Yeast    28 PLTEGDIQVLKSYGAAPYAAKLKQTENDLKDIEARIKEKAGV--------KESDTGLAPS----- 79

  Fly   167 DPDIWTPPPKDPDVWGPPKPPPTTQAVGRRAAPNNRRTTPATQNSRPSSTIPQSTARNGPASTRN 231
              .:|       |:.|      ..|.:|........|.|...:.:..|.........:|.:::.:
Yeast    80 --HLW-------DIMG------DRQRLGEEHPLQVARCTKIIKGNGESDETTTDNNNSGNSNSNS 129

  Fly   232 SRNSTSATAPSGGARTTNGRAGGRKLSTSNTNEARDDDSTAAGNNGGAA----GDGENGDPQAAQ 292
            ::.||.|                         :..|:|:....|....|    |.||...|...:
Yeast   130 NQQSTDA-------------------------DEDDEDAKYVINLKQIAKFVVGLGERVSPTDIE 169

  Fly   293 E------EERKFQPNNHIEAELVDILERDI----LQKDPKVRWSDIADLHDAKRLLEEAVVLPML 347
            |      :..|:    :||..|...::..:    :::.|.|.:||:....|....|.|.|.||:|
Yeast   170 EGMRVGVDRSKY----NIELPLPPRIDPSVTMMTVEEKPDVTYSDVGGCKDQIEKLREVVELPLL 230

  Fly   348 MPDYFK--GIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSATLTSKYRGESEKMVRLL 410
            .|:.|.  ||..| ||:|:.||||||||:.|:|||.....||..|..:.|..||.||..:|||.|
Yeast   231 SPERFATLGIDPP-KGILLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVREL 294

  Fly   411 FEMARFYAPSTIFIDEIDSLCSRR---GSESEHEASRRVKSELLVQMDGVGGGEEQAKVVMVLAA 472
            |||||......||.||||::...|   |:..::|. :|...||:.|:||.    :....:.|:.|
Yeast   295 FEMARTKKACIIFFDEIDAVGGARFDDGAGGDNEV-QRTMLELITQLDGF----DPRGNIKVMFA 354

  Fly   473 TNFPWDIDEALRR--RLEKRIYIPLPSDEGREALLKINLREVKVDDSVDLTYVANELKGYSGADI 535
            ||.|..:|.||.|  |:::::...||..|||..:.:|:.:.:.|:..:....::......:||::
Yeast   355 TNRPNTLDPALLRPGRIDRKVEFSLPDLEGRANIFRIHSKSMSVERGIRWELISRLCPNSTGAEL 419

  Fly   536 TNVCREASMMSMRRKIAGLTPEQIRQLATEEVDLPVSNKDFNEAMSRCNKSVSRADLDKYEKWMR 600
            .:||.||.|.::|.:         |::|||        |||.:|            :||.....:
Yeast   420 RSVCTEAGMFAIRAR---------RKVATE--------KDFLKA------------VDKVISGYK 455

  Fly   601 EFGSS 605
            :|.|:
Yeast   456 KFSST 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	Kp60-NTD	62..129	CDD:439297	6/26 (23%)
		PHA03291	<167..>253	CDD:223033	12/85 (14%)
		SpoVK	219..566	CDD:440232	108/367 (29%)
		RecA-like_KTNA1	327..493	CDD:410930	70/172 (41%)
		Vps4_C	<570..603	CDD:462762	6/32 (19%)
RPT1	NP_012777.1	PRK03992	154..466	CDD:179699	109/346 (32%)