DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Kat60 and CCP1

DIOPT Version :9

Sequence 1:	NP_001262276.1	Gene:	Kat60 / 53566	FlyBaseID:	FBgn0040208	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_973600.1	Gene:	CCP1 / 818020	AraportID:	AT2G34560	Length:	393	Species:	Arabidopsis thaliana

Alignment Length:	377	Identity:	161/377 - (42%)
Similarity:	244/377 - (64%)	Gaps:	29/377 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 NGRAGGRKLSTSN-TNEARDDDSTAAGNNGGAAG--------DGE----NGDPQAAQEEERKFQP 300
            :.:.|.:||...: :|:.:.:|.::.||||....        ||.    ||:....:.::..|.|
plant    21 DAKFGRKKLPEEDVSNKDQPEDGSSNGNNGDVNNNSSPVTNQDGNTALANGNVIREKPKKSMFPP 85

  Fly   301 NNHIEAE-LVDILERDILQKDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFKGIRRPWKGVLM 364
            ....|.. |.:.|.|||::.:|.::|..|..|.:||:||:||||:|:..|.||.|:..||||:|:
plant    86 FESAETRTLAESLSRDIIRGNPNIKWESIKGLENAKKLLKEAVVMPIKYPTYFNGLLTPWKGILL 150

  Fly   365 VGPPGTGKTMLAKAVATECGTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDS 429
            .||||||||||||||||||.|||||:|::::.||:||:|||::|:||::||.:||||||:||||:
plant   151 FGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLIRVLFDLARHHAPSTIFLDEIDA 215

  Fly   430 LCSRRGSE--SEHEASRRVKSELLVQMDGVGGGEEQAKVVMVLAATNFPWDIDEALRRRLEKRIY 492
            :.|:||.|  ||||||||:|:|||:||||:   ::..::|.||||||.||::|.|:.|||||||.
plant   216 IISQRGGEGRSEHEASRRLKTELLIQMDGL---QKTNELVFVLAATNLPWELDAAMLRRLEKRIL 277

  Fly   493 IPLPSDEGREALLKINLREVKVDDSVDLTYVANELKGYSGADITNVCREASMMSMRRKIAGLTPE 557
            :|||..|.|..:.::.:.....|:.:....:..:.:||||:||..:|:||:|..:||.:|.|
plant   278 VPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRILCKEAAMQPLRRTLAIL--- 339

  Fly   558 QIRQLATEEVDL----PVSNKDFNEAMSRCNKSVS-RADLDKYEKWMREFGS 604
            :.|:....|.:|    |:..:|.:.|:|....|.. .|.|  |:|:..::||
plant   340 EDREDVVPEDELPKIGPILPEDIDRALSNTRPSAHLHAHL--YDKFNDDYGS 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693
		P-loop_NTPase	325..>381	CDD:304359	35/55 (64%)
		AAA	358..496	CDD:214640	90/139 (65%)
		AAA	362..495	CDD:278434	85/134 (63%)
		Vps4_C	<570..603	CDD:286426	9/33 (27%)
CCP1	NP_973600.1	RecA-like_VPS4-like	114..278	CDD:410917	104/166 (63%)
CCP1	NP_973600.1	AAA_lid_3	306..343	CDD:407720	14/39 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810