DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kat60 and gk5

DIOPT Version :9

Sequence 1:	NP_001262276.1	Gene:	Kat60 / 53566	FlyBaseID:	FBgn0040208	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_001071271.3	Gene:	gk5 / 777765	ZFINID:	ZDB-GENE-061110-49	Length:	529	Species:	Danio rerio

Alignment Length:	154	Identity:	31/154 - (20%)
Similarity:	51/154 - (33%)	Gaps:	59/154 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 CLSFLATMTTTCSDRQLLRG--------GKQKTTTCVGMTVMAKTTFEE---ICEN--------A 67
            |.||:....:| :.|.|:|.        .||.....:..|.:..|....   :|.|        .
Zfish   384 CASFMGLKPST-TKRHLVRAILESIAFRNKQLFDVMLRETRIPITKIRADGGVCTNDFIMQLTAD 447

  Fly    68 KLARDMALTGNYDSACI---YYEGL------------------QGLLARQLKATADP--LRKG-- 107
            .|.|.:|...::|.:|:   :..||                  |..|.|:.|:..:.  |.:|
Zfish   448 LLGRKIARPSHFDMSCLGAAFVAGLGTGYWRNQEELKKLLSTDQHFLPRRSKSEGEKGGLYRGVL 512

  Fly   108 -KWSMINQQISQEHAKIKAIQRTL 130
             .|.             ||:||::
Zfish   513 QSWE-------------KALQRSM 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693
		P-loop_NTPase	325..>381	CDD:304359
		AAA	358..496	CDD:214640
		AAA	362..495	CDD:278434
		Vps4_C	<570..603	CDD:286426
gk5	NP_001071271.3	GlpK	14..525	CDD:223628	31/154 (20%)
gk5	NP_001071271.3	FGGY_GK5_metazoa	14..522	CDD:212665	30/151 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900