DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kat60 and vps4a

DIOPT Version :9

Sequence 1:NP_001262276.1 Gene:Kat60 / 53566 FlyBaseID:FBgn0040208 Length:605 Species:Drosophila melanogaster
Sequence 2:NP_001070077.1 Gene:vps4a / 767670 ZFINID:ZDB-GENE-060929-388 Length:440 Species:Danio rerio


Alignment Length:344 Identity:142/344 - (41%)
Similarity:199/344 - (57%) Gaps:52/344 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   251 RAGGRKLSTSNTNEARDDDSTAAGNNGGAAGDGENGDPQAAQEEERKFQPNNHIEAELVDILERD 315
            :.|.:.:..:.:|:..|.||           :|||.:.:..||         |:...:|      
Zfish    79 KQGKKPVKETQSNDKSDSDS-----------EGENPEKKKLQE---------HLMGAIV------ 117

  Fly   316 ILQKDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFKGIRRPWKGVLMVGPPGTGKTMLAKAVA 380
              .:.|.|||||:|.|..||..|:|||:||:..|..|.|.|.||:|:|:.|||||||:.||||||
Zfish   118 --MEKPNVRWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVA 180

  Fly   381 TEC-GTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGSESEHEASR 444
            ||. .:|||:|||:.|.||:.|||||:|:.||::||.:.||.|||||:||||..| :|:|.||:|
Zfish   181 TEANNSTFFSVSSSDLMSKWLGESEKLVKNLFDLARQHKPSIIFIDEVDSLCGSR-NENESEAAR 244

  Fly   445 RVKSELLVQMDGVGGGEEQAKVVMVLAATNFPWDIDEALRRRLEKRIYIPLPSDEGREALLKINL 509
            |:|:|.||||.|||...:.   ::||.|||.||.:|.|:|||.|||||||||.:..|.|:.:::|
Zfish   245 RIKTEFLVQMQGVGNNNDG---ILVLGATNIPWVLDAAIRRRFEKRIYIPLPEEPARSAMFRLHL 306

  Fly   510 REVKVD-DSVDLTYVANELKGYSGADITNVCREASMMSMRRKIAGLTPEQIRQLATEEVDLPVSN 573
            ...... ...||..:|.:..|||||||:.:.|:|.|..:|:..:....:::|             
Zfish   307 GNTPHSLTEADLRQLARKTDGYSGADISIIVRDALMQPVRKVQSATHFKKVR------------- 358

  Fly   574 KDFNEAMSRCNKSVSRADL 592
                 ..||.|.:|...||
Zfish   359 -----GPSRSNSAVIVDDL 372

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kat60NP_001262276.1 HCV_NS5a_C <163..243 CDD:289693
P-loop_NTPase 325..>381 CDD:304359 33/55 (60%)
AAA 358..496 CDD:214640 84/138 (61%)
AAA 362..495 CDD:278434 80/133 (60%)
Vps4_C <570..603 CDD:286426 6/23 (26%)
vps4aNP_001070077.1 MIT_VPS4 4..79 CDD:239141 142/344 (41%)
P-loop_NTPase 125..>181 CDD:304359 33/55 (60%)
AAA 158..294 CDD:214640 85/139 (61%)
AAA 162..292 CDD:278434 80/133 (60%)
Vps4_C 373..>403 CDD:286426 142/344 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170593593
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.840

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