Protein Alignment Kat60 and Atad2

DIOPT Version :10

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_081711.2
• Gene: Atad2 / 70472
• MGIID: 1917722
• Length: 1364
• Species: Mus musculus
• Alignment Length: 695
• Identity: 181/695 - (26%)
• Similarity: 292/695 - (42%)
• Gaps: 135/695 - (19%)

  Fly     2 SITQHLEKLTHSSALIGTNLCLSFLATMTTTCSDRQLLRGGKQKTTTCV---GMTVMAKTTF--- 60
            |:..| .:.|.|||....:|...||:...:.....:|.|.|::.|.:..   |.||....|:
Mouse     7 SLELH-SRSTTSSATDSLDLSSEFLSLQDSGGRRPRLRRAGRKSTASKAAGDGFTVKGAETYHNT 70

  Fly    61 ---EEICENAKLARDMALTGNYDSACIYYEG--------------------------LQGLLARQ 96
               ..:...|:.:.:.:...|.|....|..|                          ::.|..|.
Mouse    71 RSLRSLRNQAQTSSESSFDKNVDRTEKYSNGRHFTRQFARQQADKKEECKEDKVIPVIRSLRNRN 135

  Fly    97 LKATADPLR--------------KGKWSMINQQ-------------ISQEHAKIKAIQR----TL 130
            :..||:.|.              :.::|.:||.             :.|:...:|.::|    .|
Mouse   136 IAPTAEHLHEQSGDVEVRRSCRIRSRYSTMNQSVLFDKLITNTAEAVLQKMDDMKKMRRQRMKKL 200

  Fly   131 QDISLDLQS--------TKFAHKLRHQLSEESTTSKDPSAWF------KPDPDIWTPPPKDPDVW 181
            :|:.:..::        |:...|...:..||:|.::|.|...      :.|.|     .:|.|..
Mouse   201 EDLGVFNETEESNLTMYTRGKLKAIQRADEETTDNQDGSVESSEEGEEQEDDD-----GEDEDDE 260

  Fly   182 GPPKPPPTTQAVGRRAAPNNRRTTPATQN---SRPSSTIPQSTARNGPASTRNSRNSTSATAP-S 242
            ...:.....|   :|.....|:||...|:   |:|......:...:||||....|...|:|.| |
Mouse   261 DEEEGEEDNQ---KRYYLRQRKTTVYYQSPLESKPRHQRKPNMFYSGPASPARPRFRLSSTGPRS 322

  Fly   243 GGARTTNGRAGGRKLSTSNTNEARDDD----STAAGNNGGAAGDGENGDPQAAQEEERK--FQPN 301
            ...:..:.|......|.|.::.:.:||    .|....|...    ....|...:::|.:  ::..
Mouse   323 PYCKRMSRRRHAIHSSDSTSSSSSEDDCFERRTKRNRNRAI----NRCLPLNFRKDEIRGIYKDR 383

  Fly   302 NHIEAELVDILERDILQKDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFKGIR-RPWKGVLMV 365
            ..|.|.|.|:   |.:|.|..||:..:..|......|:|.||.|:|.|:.|:..: :|.:|.|..
Mouse   384 MKIGASLADV---DPMQLDTSVRFDSVGGLSSHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFY 445

  Fly   366 GPPGTGKTMLAKAVATECG-----TTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFID 425
            ||||||||::|:|:|.||.     ..||....|...||:.||||:.:||||:.|....|:.||.|
Mouse   446 GPPGTGKTLVARALANECSRGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPAIIFFD 510

  Fly   426 EIDSLCSRRGSESEHEASRRVKSELLVQMDGVGGGEEQAKVVMVLAATNFPWDIDEALRR--RLE 488
            |||.|...|.|..: :....:.|.||..|||:....|    ::|:.|||....||.||||  |.:
Mouse   511 EIDGLAPVRSSRQD-QIHSSIVSTLLALMDGLDSRGE----IVVIGATNRLDSIDPALRRPGRFD 570

  Fly   489 KRIYIPLPSDEGREALLKINLRE---VKVDDSVDLTYVANELKGYSGADITNVCREASMMSMRRK 550
            :.....||....|:.:|||:.|:   ..||  :.|..:|....||.||||.::|.||::.::||:
Mouse   571 REFLFSLPDKNARKEILKIHTRDWNPKPVD--MFLEELAEHCVGYCGADIKSICAEAALCALRRR 633

  Fly   551 IAGL--TPEQIRQLATEEVDL---PVSNKDFNEAMSRCNKSVSRA 590
            ...:  |.|::      ::||   .:|.|||..|:.:...:..||
Mouse   634 YPQIYTTSEKL------QLDLSSITISAKDFEAALQKIRPASQRA 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	Kp60-NTD	62..129	CDD:439297	16/123 (13%)
		PHA03291	<167..>253	CDD:223033	22/89 (25%)
		SpoVK	219..566	CDD:440232	118/366 (32%)
		RecA-like_KTNA1	327..493	CDD:410930	67/173 (39%)
		Vps4_C	<570..603	CDD:462762	7/21 (33%)
Atad2	NP_081711.2	RecA-like_Yta7-like	406..575	CDD:410925	67/173 (39%)
		AAA_lid_3	603..637	CDD:465537	13/33 (39%)
		ycf46	<766..907	CDD:177094
		Bromo_AAA	960..1070	CDD:99957