Protein Alignment Kat60 and Fignl1

DIOPT Version :9

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_011242039.1
• Gene: Fignl1 / 60530
• MGIID: 1890648
• Length: 692
• Species: Mus musculus
• Alignment Length: 666
• Identity: 208/666 - (31%)
• Similarity: 305/666 - (45%)
• Gaps: 161/666 - (24%)

  Fly    54 VMAKTTFEEICE--NAKLARDMALTG--NYDSACIYYEGLQGLLARQLKATADPLRKGKWSMINQ 114
            |.|...|:...|  :|.:..|..:||  ||..:.....|     :||    ||   ..||   ..
Mouse    69 VFATNLFKRYTEKYSAIIDSDNVVTGLNNYAESIFALAG-----SRQ----AD---SNKW---QS 118

  Fly   115 QISQEHA-KIKAIQRTLQDISLDLQSTKFAHKLRHQLSEESTTSKDPSAWFKP---------DPD 169
            .:|.::. |:..:|..:|      ...||...|...........|:|:|:..|         |.|
Mouse   119 GLSIDNVFKMSCVQEMMQ------AGKKFEESLLEPADASVVLCKEPTAFEVPQLSVCGGSEDAD 177

  Fly   170 IWTPPPKDPDVWGPPKPPPTTQAV---GRRAAP----------NNRRT----------------- 204
            |.:....|.|         .|||:   ..|.:|          |..:|
Mouse   178 ILSSSGHDTD---------KTQAIPGSSLRCSPFQSARLPKETNTTKTCLTSSTSLGESATAAFH 233

  Fly   205 -TPATQNS-RPSSTIPQ-STARN--------GPASTRNSR---------------NSTSATAPS- 242
             ||...|: :.:.:.|: ||..|        .|:...|.:               |.|...|||
Mouse   234 MTPLFGNTEKDTQSFPKTSTGLNMFLSNLSCVPSGCENPQERKAFNDSDIIDILSNPTLNKAPSK 298

  Fly   243 ---GGARTTNG----------------RAGGRKLSTSNTNEARDDDSTAAGNNGGAAG------- 281
               .|.|..|.                :.|.:...||.::......|..||.:.|..|
Mouse   299 TEDRGRREDNSLPTFKTAKEQLWVDQKKKGHQSQHTSKSSNGVMKKSLGAGRSRGIFGKFVPPVS 363

  Fly   282 DGENGDPQAAQEEER----KFQPNN-------HIEAELVDILERDILQKDPKVRWSDIADLHDAK 335
            :.::|..|.|::.:.    ..:|.:       ::|..:|:::..:|:...|.|.|.|||.:..||
Mouse   364 NKQDGSEQHAKKHKSSRAGSAEPAHLTDDCLKNVEPRMVELIMNEIMDHGPPVHWDDIAGVEFAK 428

  Fly   336 RLLEEAVVLPMLMPDYFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSATLTSKYR 400
            ..::|.||.||:.||.|.|:|.|.||:|:.||||||||::.|.:|::.|.|||::|:::||||:.
Mouse   429 ATIKEIVVWPMMRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWV 493

  Fly   401 GESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGSESEHEASRRVKSELLVQMDGVGGGEEQAK 465
            ||.|||||.||.:||...|:.|||||||||.|:|| :.|||:|||:|:|.|||:||.....|..
Mouse   494 GEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRG-DGEHESSRRIKTEFLVQLDGATTSSEDR- 556

  Fly   466 VVMVLAATNFPWDIDEALRRRLEKRIYIPLPSDEGREALLKINLREVK----VDDSVDLTYVANE 526
             ::|:.|||.|.:||||.||||.||:|||||....|:.::. ||...:    .|:..||  |..:
Mouse   557 -ILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVG-NLMSKEQCCLSDEETDL--VVQQ 617

  Fly   527 LKGYSGADITNVCREASMMSMR----RKIAGLTPEQIRQLATEEVDLPVSNKDFNEAMSRCNKSV 587
            ..|:||||:|.:|||||:..:|    ..||.::|:|:|         |::..||..|......:|
Mouse   618 SDGFSGADMTQLCREASLGPIRSLHAADIATISPDQVR---------PIAYIDFENAFKTVRPTV 673

  Fly   588 SRADLDKYEKWMREFG 603
            |..||:.||.|...||
Mouse   674 SPKDLELYENWNETFG 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693	27/148 (18%)
		P-loop_NTPase	325..>381	CDD:304359	29/55 (53%)
		AAA	358..496	CDD:214640	79/137 (58%)
		AAA	362..495	CDD:278434	75/132 (57%)
		Vps4_C	<570..603	CDD:286426	11/32 (34%)
Fignl1	XP_011242039.1	RecA-like_Figl-1	398..583	CDD:410933	97/187 (52%)
		AAA_lid_3	608..>639	CDD:407720	15/32 (47%)
		Vps4_C	<649..689	CDD:401324	14/48 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848174
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840