Protein Alignment Kat60 and fignl1

DIOPT Version :9

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001122223.1
• Gene: fignl1 / 569539
• ZFINID: ZDB-GENE-030131-1862
• Length: 661
• Species: Danio rerio
• Alignment Length: 615
• Identity: 204/615 - (33%)
• Similarity: 293/615 - (47%)
• Gaps: 125/615 - (20%)

  Fly    86 YEGLQGL------LARQLKATADPLRKGKW--SMINQQISQEHAKIKAIQRTLQDISLDLQSTKF 142
            |:||...      |||..|..:|     ||  |:..:.:.......|.||......:|.:.....
Zfish    72 YKGLNNYAETALHLARNQKNHSD-----KWESSLTLENVFNLSCVQKMIQARSDGCALPVDPADV 131

  Fly   143 AHKLRHQLS---EESTTSKDPSAWFKPDPDIWTPPPKDPDVWGPPKPPPTTQAV----------- 193
            ...:..::|   |:.::...|.:..|          ::|...|...|.||.:..
Zfish   132 NISVGGEVSGGGEKGSSLSGPPSGLK----------QEPLAHGHSVPLPTAEMARGDINPISGSG 186

  Fly   194 GRRAAPNNRRTTPATQNSRPSSTI--------------PQS----TAR----NGP---ASTRNSR 233
            |...||........|......|||              |||    |:|    |.|   :||..|:
Zfish   187 GLEVAPPRFSLAQNTPKGLTGSTIFGHNNFGSTGNAVVPQSNVACTSRSNVHNQPVFFSSTNPSK 251

  Fly   234 ---------NSTSATAPSGGARTTNGRA--GGRKLSTSNTNEARD----DDSTAAGNNG--GAAG 281
                     .|:.::.||.|.:...||.  |...:|| |...||:    |......:.|  |:.|
Zfish   252 RKNFYGSGTESSRSSFPSQGEQELRGRGLRGEEGIST-NFRSAREQFIVDQQKKHSHQGQRGSPG 315

  Fly   282 D---------GENG---------DPQAAQEEERK------FQPNN----HIEAELVDILERDILQ 318
            :         |.|.         .|...|||:.|      .||.:    :.|.::::::..:|:.
Zfish   316 NVFTITKKCLGANRSRGASSKFISPMPRQEEDLKDNTPKDMQPVDERLKNFEPKIIELIMSEIMD 380

  Fly   319 KDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFKGIRRPWKGVLMVGPPGTGKTMLAKAVATEC 383
            ..|.|.|.|||.|..||..::|.||.|||.||.|.|:|.|.||:|:.||||||||::.|.:|.:.
Zfish   381 HGPPVAWDDIAGLEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIACQS 445

  Fly   384 GTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGSESEHEASRRVKS 448
            |.|||::|:::||||:.||.|||||.||.:||.:.|:.|||||||||.|:| ::.||::|||:|:
Zfish   446 GATFFSISASSLTSKWVGEGEKMVRALFAIARCHQPAVIFIDEIDSLLSQR-TDGEHDSSRRIKT 509

  Fly   449 ELLVQMDGVGGGEEQAKVVMVLAATNFPWDIDEALRRRLEKRIYIPLPSDEGREALLKINLREVK 513
            |.|||:||.....|..  ::|:.|||.|.:||||.||||.||:|||||..|.|..::...:...|
Zfish   510 EFLVQLDGAATSAEDR--ILVVGATNRPQEIDEAARRRLAKRLYIPLPEAEARRQIVTNLMSHEK 572

  Fly   514 VDDSVD-LTYVANELKGYSGADITNVCREASMMSMR----RKIAGLTPEQIRQLATEEVDLPVSN 573
            ....|| :..|....:|:||||:|.:||||::..:|    ..||.:..||:|         |:..
Zfish   573 SQLGVDEMEKVVQGTEGFSGADMTQLCREAALGPIRSISLSDIATIMAEQVR---------PILY 628

  Fly   574 KDFNEAMSRCNKSVSRADLDKYEKWMREFG 603
            .||.||:.....|||..||:.||:|.:.||
Zfish   629 SDFQEALKTVRPSVSSKDLELYEEWNKTFG 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693	25/124 (20%)
		P-loop_NTPase	325..>381	CDD:304359	31/55 (56%)
		AAA	358..496	CDD:214640	77/137 (56%)
		AAA	362..495	CDD:278434	73/132 (55%)
		Vps4_C	<570..603	CDD:286426	13/32 (41%)
fignl1	NP_001122223.1	AAA	420..556	CDD:214640	78/138 (57%)
		AAA	424..554	CDD:278434	73/132 (55%)
		Vps4_C	<610..658	CDD:286426	18/56 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593576
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840