Protein Alignment Kat60 and fignl1

DIOPT Version :10

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001122223.1
• Gene: fignl1 / 569539
• ZFINID: ZDB-GENE-030131-1862
• Length: 661
• Species: Danio rerio
• Alignment Length: 615
• Identity: 204/615 - (33%)
• Similarity: 293/615 - (47%)
• Gaps: 125/615 - (20%)

  Fly    86 YEGLQGL------LARQLKATADPLRKGKW--SMINQQISQEHAKIKAIQRTLQDISLDLQSTKF 142
            |:||...      |||..|..:|     ||  |:..:.:.......|.||......:|.:.....
Zfish    72 YKGLNNYAETALHLARNQKNHSD-----KWESSLTLENVFNLSCVQKMIQARSDGCALPVDPADV 131

  Fly   143 AHKLRHQLS---EESTTSKDPSAWFKPDPDIWTPPPKDPDVWGPPKPPPTTQAV----------- 193
            ...:..::|   |:.::...|.:..|          ::|...|...|.||.:..
Zfish   132 NISVGGEVSGGGEKGSSLSGPPSGLK----------QEPLAHGHSVPLPTAEMARGDINPISGSG 186

  Fly   194 GRRAAPNNRRTTPATQNSRPSSTI--------------PQS----TAR----NGP---ASTRNSR 233
            |...||........|......|||              |||    |:|    |.|   :||..|:
Zfish   187 GLEVAPPRFSLAQNTPKGLTGSTIFGHNNFGSTGNAVVPQSNVACTSRSNVHNQPVFFSSTNPSK 251

  Fly   234 ---------NSTSATAPSGGARTTNGRA--GGRKLSTSNTNEARD----DDSTAAGNNG--GAAG 281
                     .|:.::.||.|.:...||.  |...:|| |...||:    |......:.|  |:.|
Zfish   252 RKNFYGSGTESSRSSFPSQGEQELRGRGLRGEEGIST-NFRSAREQFIVDQQKKHSHQGQRGSPG 315

  Fly   282 D---------GENG---------DPQAAQEEERK------FQPNN----HIEAELVDILERDILQ 318
            :         |.|.         .|...|||:.|      .||.:    :.|.::::::..:|:.
Zfish   316 NVFTITKKCLGANRSRGASSKFISPMPRQEEDLKDNTPKDMQPVDERLKNFEPKIIELIMSEIMD 380

  Fly   319 KDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFKGIRRPWKGVLMVGPPGTGKTMLAKAVATEC 383
            ..|.|.|.|||.|..||..::|.||.|||.||.|.|:|.|.||:|:.||||||||::.|.:|.:.
Zfish   381 HGPPVAWDDIAGLEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIACQS 445

  Fly   384 GTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGSESEHEASRRVKS 448
            |.|||::|:::||||:.||.|||||.||.:||.:.|:.|||||||||.|:| ::.||::|||:|:
Zfish   446 GATFFSISASSLTSKWVGEGEKMVRALFAIARCHQPAVIFIDEIDSLLSQR-TDGEHDSSRRIKT 509

  Fly   449 ELLVQMDGVGGGEEQAKVVMVLAATNFPWDIDEALRRRLEKRIYIPLPSDEGREALLKINLREVK 513
            |.|||:||.....|..  ::|:.|||.|.:||||.||||.||:|||||..|.|..::...:...|
Zfish   510 EFLVQLDGAATSAEDR--ILVVGATNRPQEIDEAARRRLAKRLYIPLPEAEARRQIVTNLMSHEK 572

  Fly   514 VDDSVD-LTYVANELKGYSGADITNVCREASMMSMR----RKIAGLTPEQIRQLATEEVDLPVSN 573
            ....|| :..|....:|:||||:|.:||||::..:|    ..||.:..||:|         |:..
Zfish   573 SQLGVDEMEKVVQGTEGFSGADMTQLCREAALGPIRSISLSDIATIMAEQVR---------PILY 628

  Fly   574 KDFNEAMSRCNKSVSRADLDKYEKWMREFG 603
            .||.||:.....|||..||:.||:|.:.||
Zfish   629 SDFQEALKTVRPSVSSKDLELYEEWNKTFG 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	Kp60-NTD	62..129	CDD:439297	14/50 (28%)
		PHA03291	<167..>253	CDD:223033	28/132 (21%)
		SpoVK	219..566	CDD:440232	157/407 (39%)
		RecA-like_KTNA1	327..493	CDD:410930	91/165 (55%)
		Vps4_C	<570..603	CDD:462762	13/32 (41%)
fignl1	NP_001122223.1	RecA-like_Figl-1	367..552	CDD:410933	96/187 (51%)
		AAA_lid_3	579..615	CDD:465537	12/35 (34%)
		Vps4_C	<610..658	CDD:462762	18/56 (32%)