Protein Alignment Kat60 and fign

DIOPT Version :10

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_021334341.1
• Gene: fign / 553599
• ZFINID: ZDB-GENE-050522-339
• Length: 747
• Species: Danio rerio
• Alignment Length: 682
• Identity: 176/682 - (25%)
• Similarity: 284/682 - (41%)
• Gaps: 183/682 - (26%)

  Fly    83 CIYYEGLQGLLARQLKATADPLRKGKWSMINQQISQEHAKIKAIQRT-------LQDISLDLQST 140
            |.|.|...|||..: |:.:|..::|.:.|      ...|.:.:..:|       ..|::..:.|:
Zfish    89 CSYSESAPGLLNGR-KSESDAWQEGIYPM------SCAADVISASKTGMTPALPPPDVTASVGSS 146

  Fly   141 KFAHKLRHQLSEESTTSKD------------PSAWF----------------KPDPDIWTPPPKD 177
            .   .:...|||.|.:|.:            ||..|                :..|.:.:|.|..
Zfish   147 T---GVASSLSEPSYSSSNCGNHASALHSGIPSQEFASSYNGSYLHSTYSGGQSTPALPSPHPSP 208

  Fly   178 PDVWG----PPKPPPTTQAVGRRAAPNNRR----------TTP---------------------A 207
            ....|    ||.||||.......::||...          .||                     |
Zfish   209 LHSAGLLQPPPPPPPTLVPSYNTSSPNLSSYNYPPAGYPPQTPVAPGYSPGGAPPPSAYLPSGIA 273

  Fly   208 TQNSRPSSTIP----QS--------TARNGPASTR---------------------NSRNSTSAT 239
            .....|.||||    ||        |..||.::..                     |.....||.
Zfish   274 APTPLPPSTIPGYSYQSHNHAPIAPTPLNGSSANTLKRKAFYMTGQGDMDSSYGNFNYSQQRSAQ 338

  Fly   240 AP------SGGARTTNGRAGGRKLSTSN-----------TNEARDDDSTAA--------GNNGGA 279
            :|      :....:|.|....|...||:           |::.|...|.|.        |::.|:
Zfish   339 SPMYRMPDNSLVDSTRGNGFDRNADTSSLAFKPTKQSMPTDQQRKFGSQAGRALTPPSYGSSKGS 403

  Fly   280 AGD-------GENGDPQAAQ--EEERKFQPNN----------------HIEAELVDILERDILQK 319
            .|.       |:.|.|..:.  ::.|:..|::                :.:|.||:::..:|||:
Zfish   404 LGSMRSGESFGKFGSPVMSDHGDDSRQHLPHSIGTATSSSHPAEEQLKNSDASLVEMVTTEILQQ 468

  Fly   320 DPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECG 384
            .|.|.|||||.|..||..:::.|:.|:|.||.|.|:....:.:|:.||.|||:|:|.:.:|::.|
Zfish   469 TPPVDWSDIAGLEMAKATIKDEVLWPILRPDMFSGLATLPRSILLFGPQGTGRTLLGRCMASQLG 533

  Fly   385 TTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGSESEHEASRRVKSE 449
            ..|..:|.:.|.:|:.||.||:|:..|.:||...||.:||.::|.|.|  ...||.....|:|||
Zfish   534 AAFLLLSGSALVTKWLGEGEKIVQASFLIARCRQPSVVFISDVDLLLS--SQLSEESPVNRIKSE 596

  Fly   450 LLVQMDGVGGGEEQAKVVMVLAATNFPWDIDEALRRRLEKRIYIPLPSDEGREALLK--INLREV 512
            ||:|:|||....|:.  |:|:.:|:.|.:|||:|||...||:.:|||....|..::.  ::....
Zfish   597 LLLQLDGVLSSPEEH--VLVVCSTSKPEEIDESLRRYFVKRLLVPLPDATARHQIISQLLSQHNY 659

  Fly   513 KVDDSVDLTYVANELKGYSGADITNVCREASMMSMR----RKIAGLTPEQIRQLATEEVDLPVSN 573
            .:.|. ::|.:.....|:||.|:..:|:||.:..:.    ..::|:.|.|:|         |||.
Zfish   660 CLSDK-EVTLLVQRTDGFSGLDVVRLCQEALVGPLHGMPGADLSGMIPGQMR---------PVSY 714

  Fly   574 KDFNEAMSRCNKSVSRADLDKYEKWMREFGSS 605
            :||.....:...|:|:.:||.|.:|.:.||.|
Zfish   715 QDFENVFCKIQPSISQKELDTYTEWNKMFGCS 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	Kp60-NTD	62..129	CDD:439297	11/45 (24%)
		PHA03291	<167..>253	CDD:223033	31/159 (19%)
		SpoVK	219..566	CDD:440232	120/431 (28%)
		RecA-like_KTNA1	327..493	CDD:410930	67/165 (41%)
		Vps4_C	<570..603	CDD:462762	11/32 (34%)
fign	XP_021334341.1	PHA03378	<174..300	CDD:223065	25/125 (20%)
		RecA-like_fidgetin	476..638	CDD:410931	67/165 (41%)
		AAA_lid_3	669..>694	CDD:465537	7/24 (29%)
		Vps4_C	<711..744	CDD:462762	11/32 (34%)