Protein Alignment Kat60 and FIGN

DIOPT Version :9

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_011509691.1
• Gene: FIGN / 55137
• HGNCID: 13285
• Length: 785
• Species: Homo sapiens
• Alignment Length: 622
• Identity: 151/622 - (24%)
• Similarity: 252/622 - (40%)
• Gaps: 180/622 - (28%)

  Fly   129 TLQDISLDLQSTKFAHKLRHQLSEESTTSKDPSAWFKPDPD------IWTPPPKDPDVWGPPKPP 187
            |:..:...|.|.::|..........:.:|:...|...|.|.      :..|||       ||.||
Human   198 TVPSLHAGLPSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPP-------PPPPP 255

  Fly   188 PTTQAVGRRAAPNNRRTTPATQNSRPSSTIPQSTARNGPASTRNSRNSTSATAPSG--------- 243
            |.       ..|....|:..:..|.||::.|..||.....|...:....||..|||
Human   256 PA-------LVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPP 313

  Fly   244 -----------------GARTTNGRAG------------------------GRKLSTSNTNEARD 267
                             .:..||..|.                        |::.||.:......
Human   314 TTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMP 378

  Fly   268 DDSTAAGNNGGAAGDGENGDPQAAQ---------------EEERKFQ------------------ 299
            |:|.:..|.|       ||..::|:               |::|||.
Human   379 DNSISNTNRG-------NGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNS 436

  Fly   300 -----------------------------------------PNNH--------IEAELVDILERD 315
                                                     .:||        .:..|:|::..:
Human   437 LGSRSSESFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNE 501

  Fly   316 ILQKDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFKGIRRPWKGVLMVGPPGTGKTMLAKAVA 380
            |:.:.|.|.|:|||.|...|.:::|.|:.|:|..|.|.|:....:.:|:.||.|||||:|.:.:|
Human   502 IITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIA 566

  Fly   381 TECGTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGSESEHEASRR 445
            ::.|.|||.::.:.|.:|:.||:||::...|.:||...||.||:.:||.|.|.:.:| ||....|
Human   567 SQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNE-EHSPVSR 630

  Fly   446 VKSELLVQMDGV-GGGEEQAKVVMVLAATNFPWDIDEALRRRLEKRIYIPLPSDEGREALL--KI 507
            :::|.|:|:|.| ...|:|   ::|:.||:.|.:|||:|||...||:.||||....|..::  .:
Human   631 MRTEFLMQLDTVLTSAEDQ---IVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLL 692

  Fly   508 NLREVKVDDSVDLTYVANELKGYSGADITNVCREASMMSMR----RKIAGLTPEQIRQLATEEVD 568
            :.....::|. :...:....:|:||.|:.::|:||.:..:.    ..::.:.|.|:|
Human   693 SQHNYCLNDK-EFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQLR-------- 748

  Fly   569 LPVSNKDFNEAMSRCNKSVSRADLDKYEKWMREFGSS 605
             ||:.:||..|..:...|:|:.:||.|.:|.:.||.|
Human   749 -PVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCS 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693	22/85 (26%)
		P-loop_NTPase	325..>381	CDD:304359	22/55 (40%)
		AAA	358..496	CDD:214640	56/138 (41%)
		AAA	362..495	CDD:278434	55/133 (41%)
		Vps4_C	<570..603	CDD:286426	11/32 (34%)
FIGN	XP_011509691.1	AAA	545..680	CDD:214640	57/138 (41%)
		AAA	548..678	CDD:278434	55/133 (41%)
		Vps4_C	<749..782	CDD:286426	11/32 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157800
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840