Protein Alignment Kat60 and ATAD2B

DIOPT Version :9

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_011531220.1
• Gene: ATAD2B / 54454
• HGNCID: 29230
• Length: 1511
• Species: Homo sapiens
• Alignment Length: 583
• Identity: 157/583 - (26%)
• Similarity: 249/583 - (42%)
• Gaps: 83/583 - (14%)

  Fly    35 DRQLLRGGKQKTTTCVGMTVMAKTTFEEICENAKLARDMALTGNYDSACIYYEGLQGLLARQLKA 99
            |...:.|..:...:|..    .|..||.:  |..|..|..:....::.   .:.:..:..|:.:.
Human   155 DLSCINGDMEVRKSCRS----RKNRFESV--NQSLLFDQLVNSTAEAV---LQEMDNINIRRNRR 210

  Fly   100 TADPLRKGKWSMINQQISQEHAKIKAIQRTLQDISLDLQSTKFAHKLRHQLSEESTTSKDPSAWF 164
            :.:..|...|:....:....::::|..:::|:..|..:|:   .|::..:..||:.|||     .
Human   211 SGEVERLRMWTDTEFENMDMYSRVKRRRKSLRRNSYGIQN---HHEVSTEGEEEARTSK-----L 267

  Fly   165 KP-----------DPDIWTPPPKDPDVWGPPKPPP----TTQAVGRRAAPNNRRTTPATQNSRPS 214
            .|           |.||     :..:..|.....|    ..:.|.|..||   ...||.|..|.:
Human   268 LPLEKISIESQEEDGDI-----EVEEAEGEENDRPYNLRQRKTVDRYQAP---PIVPAHQKKREN 324

  Fly   215 S--TIPQSTARNGPASTRNSRNSTSATAPSGGARTTNGRAGGRKLSTSNTNEARDDDSTAAGNNG 277
            :  .|.:|.||......:.....:|.|..|...|.                |.|...|.|...|.
Human   325 TLFDIHRSPARRSHIRRKKHAIHSSDTTSSDEERF----------------ERRKSKSMARARNR 373

  Fly   278 GAAGDGENGDPQAAQEEERKFQPNNHIEAELVDILERDILQKDPKVRWSDIADLHDAKRLLEEAV 342
            ....:....|..:....||.     .:.|.|.|:   |.:..|..||:..|..|......|:|.|
Human   374 CLPMNFRAEDLASGILRERV-----KVGASLADV---DPMNIDKSVRFDSIGGLSHHIHALKEMV 430

  Fly   343 VLPMLMPDYFKGIR-RPWKGVLMVGPPGTGKTMLAKAVATECG-----TTFFNVSSATLTSKYRG 401
            |.|:|.|:.|:..: :|.:|.|..||||||||::|:|:|.||.     ..||....|...||:.|
Human   431 VFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFMRKGADCLSKWVG 495

  Fly   402 ESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGSESEHEASRRVKSELLVQMDGVGGGEEQAKV 466
            |||:.:||||:.|....||.||.||||.|...|.|..: :....:.|.||..|||:....|
Human   496 ESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQD-QIHSSIVSTLLALMDGLDNRGE---- 555

  Fly   467 VMVLAATNFPWDIDEALRR--RLEKRIYIPLPSDEGREALLKINLRE--VKVDDSVDLTYVANEL 527
            ::|:.|||....||.||||  |.::.....||..:.|:.:|:|:.|:  .|:.|:. |..:|.:.
Human   556 IVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQKARKHILQIHTRDWNPKLSDAF-LGELAEKC 619

  Fly   528 KGYSGADITNVCREASMMSMRRKIAGLTPEQIRQLATEEVDLPVSNKDFNEAMSRCNKSVSRA 590
            .||.||||..:|.||:::::||:...:.... .:|..:...:.:|.:||..||.....:..||
Human   620 VGYCGADIKALCTEAALIALRRRYPQIYASS-HKLQLDVSSIVLSAQDFYHAMQNIVPASQRA 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693	20/96 (21%)
		P-loop_NTPase	325..>381	CDD:304359	23/56 (41%)
		AAA	358..496	CDD:214640	59/144 (41%)
		AAA	362..495	CDD:278434	57/139 (41%)
		Vps4_C	<570..603	CDD:286426	7/21 (33%)
ATAD2B	XP_011531220.1	AAA	447..588	CDD:214640	60/145 (41%)
		AAA	452..586	CDD:278434	57/138 (41%)
		COG5076	866..>1100	CDD:227408
		Bromo_AAA	974..1085	CDD:99957

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900