DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kat60 and Rpt6R

DIOPT Version :9

Sequence 1:	NP_001262276.1	Gene:	Kat60 / 53566	FlyBaseID:	FBgn0040208	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_651811.1	Gene:	Rpt6R / 43635	FlyBaseID:	FBgn0039788	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	289	Identity:	110/289 - (38%)
Similarity:	168/289 - (58%)	Gaps:	22/289 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   297 KFQPNNHIEAELVD-ILERDILQKDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFK--GIRRP 358
            |..||.      || ::...:::|.|...:..:..|....:.::|.:.||:..|:.|.  ||.:|
  Fly   119 KILPNK------VDPLVSLMLVEKVPDSTYEMVGGLDKQIQEIKEVIELPVKHPELFDALGITQP 177

  Fly   359 WKGVLMVGPPGTGKTMLAKAVA--TECGTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPST 421
             ||||:.||||||||:||:|||  |||  ||..||.:.|..|:.||..:|||.||.|||.:|||.
  Fly   178 -KGVLLYGPPGTGKTLLARAVAHHTEC--TFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSI 239

  Fly   422 IFIDEIDSLCSRRGSESEHEAS-RRVKSELLVQMDGVGGGEEQAKVVMVLAATNFPWDIDEALRR 485
            ||:|||||:.|.|......::. :|...|||.|:||.    |..|.:.|:.|||....:|:||.|
  Fly   240 IFMDEIDSIGSARLETGTGDSEVQRTMLELLNQLDGF----EATKNIKVIMATNRIDVLDQALLR 300

  Fly   486 --RLEKRIYIPLPSDEGREALLKINLREVKVDDSVDLTYVANELKGYSGADITNVCREASMMSMR 548
              |::::|..|.|::|.|..:|||:.|::.:...::|..:|.|:.|.|||::..||.||.|.::|
  Fly   301 PGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAEEMPGASGAEVKGVCTEAGMYALR 365

  Fly   549 RKIAGLTPEQIRQLATEEVDLPVSNKDFN 577
            .:...:|.|.. ::|..:|.:..|.|:.:
  Fly   366 ERRVHVTQEDF-EMAVSKVMMKDSEKNMS 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693
		P-loop_NTPase	325..>381	CDD:304359	26/59 (44%)
		AAA	358..496	CDD:214640	69/142 (49%)
		AAA	362..495	CDD:278434	65/137 (47%)
		Vps4_C	<570..603	CDD:286426	2/8 (25%)
Rpt6R	NP_651811.1	RPT1	3..396	CDD:224143	110/289 (38%)
Rpt6R	NP_651811.1	AAA	180..311	CDD:278434	65/136 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810