Protein Alignment Kat60 and spast

DIOPT Version :9

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_998080.2
• Gene: spast / 405851
• ZFINID: ZDB-GENE-040426-2331
• Length: 570
• Species: Danio rerio
• Alignment Length: 564
• Identity: 202/564 - (35%)
• Similarity: 288/564 - (51%)
• Gaps: 96/564 - (17%)

  Fly    57 KTTFEEICENAKLARDMALTGNYDSACIYYEGLQGLLARQLKATADPLRKGKWSMINQQISQEHA 121
            |..||.|  :..|..|....|:...|..:|.          |..|: |.||      .||....|
Zfish    85 KQAFEFI--SVALQIDEDEKGDKQKAVQWYR----------KGIAE-LEKG------IQIQVTGA 130

  Fly   122 KIKAIQ-RTLQD-----ISLDLQSTKFAHKLRHQLSEESTTSKDPSAWFKPDPDIWTPPPKDPDV 180
            ..||.: |.|||     :|:.....|....|..|...||  |.|.|.:...:
Zfish   131 GEKADRARKLQDKMITNLSMAEDRLKLLGNLLSQSPAES--SSDDSFYSFSN------------- 180

  Fly   181 WGPPKPPPTTQAVGRRAAPNNRRTTPATQNSRPSSTIPQSTA---RNGPASTRNSR--NSTSATA 240
             |..:|.|.:.||.::               :.:.||...|:   :|.|.||.|:.  |.|.:.|
Zfish   181 -GNLRPAPASGAVSKK---------------KDTLTITNQTSLRPKNPPKSTPNASGLNCTPSAA 229

  Fly   241 PSGGARTTNGRAGGRKLSTSNTNEARDDDSTAAGNNGGAAGDGENGDPQAAQEEERKFQPNNHIE 305
            .|......|.:.|                .|..|.|...|.......||    .:|..:...:::
Zfish   230 QSSRTGPQNNQKG----------------PTVKGKNNVKASTTATASPQ----RKRDMKNFKNVD 274

  Fly   306 AELVDILERDILQKDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFKGIRRPWKGVLMVGPPGT 370
            ::|..::..:|:.....||:.|||....||:.|:|.|:||.|.|:.|.|:|.|.:|:|:.||||.
Zfish   275 SKLASLILNEIVDSGSVVRFDDIAGQDLAKQALQEIVILPALRPELFTGLRAPARGLLLFGPPGN 339

  Fly   371 GKTMLAKAVATECGTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDS-LCSRR 434
            ||||||||||.|...||||:|:|||||||.||.||:||.||.:||...||.|||||||| ||.||
Zfish   340 GKTMLAKAVAMESNATFFNISAATLTSKYVGEGEKLVRALFAVARELQPSIIFIDEIDSLLCERR 404

  Fly   435 GSESEHEASRRVKSELLVQMDGV-GGGEEQAKVVMVLAATNFPWDIDEALRRRLEKRIYIPLPSD 498
              |.||:||||:|:|.|::.||| .||:|:   |:|:.|||.|.::|||:.||..||||:.||::
Zfish   405 --EGEHDASRRLKTEFLIEFDGVQSGGDER---VLVMGATNRPQELDEAVLRRFAKRIYVALPTE 464

  Fly   499 EGREALLKINLREVKVD-DSVDLTYVANELKGYSGADITNVCREASMMSMRRKIAGLTPEQIRQL 562
            |.|..|||..|.:.:.. ...:|:.:|....||||:|:|::.::|::..:|.    |.|||:|.:
Zfish   465 ETRLKLLKNLLSKHRNPLSQKELSQLARLTDGYSGSDLTSLAKDAALGPIRE----LKPEQVRNM 525

  Fly   563 ATEEV-DLPVSNKDFNEAMSRCNKSVSRADLDKYEKWMREFGSS 605
            :..|: |:.:|  ||.|::.|..:|||...||:|.:|.||:|.:
Zfish   526 SAHEMRDIRIS--DFLESLKRIKRSVSPQTLDQYVRWNREYGDT 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693	16/84 (19%)
		P-loop_NTPase	325..>381	CDD:304359	31/55 (56%)
		AAA	358..496	CDD:214640	85/139 (61%)
		AAA	362..495	CDD:278434	83/134 (62%)
		Vps4_C	<570..603	CDD:286426	14/32 (44%)
spast	NP_998080.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..269		24/117 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910