DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kat60 and atad1b

DIOPT Version :9

Sequence 1:	NP_001262276.1	Gene:	Kat60 / 53566	FlyBaseID:	FBgn0040208	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_001019592.1	Gene:	atad1b / 368412	ZFINID:	ZDB-GENE-030616-44	Length:	362	Species:	Danio rerio

Alignment Length:	321	Identity:	110/321 - (34%)
Similarity:	172/321 - (53%)	Gaps:	36/321 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 DPQAAQEEERKFQPNN-----------------HIEAELVDILERDILQKDPKVRWSDIADLHDA 334
            ||...|:.|.:.|...                 .|.|.|||.|..       ::.|.|||.|.:.
Zfish    46 DPTRKQKVEAQKQAEKLMRQIGVQNVKLSEYEMSIAAHLVDPLTM-------QITWYDIAGLDEV 103

  Fly   335 KRLLEEAVVLPMLMPDYFKGIR--RPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSATLTS 397
            ...|::.|:||:.....|:|.|  :|.||||:.||||.|||::|||.|.|.|..|.|:..:|||.
Zfish   104 ITELKDTVILPIQKRHLFEGSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGFRFINLQPSTLTD 168

  Fly   398 KYRGESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGSESEHEASRRVKSELLVQMDGVGGGEE 462
            |:.|||:|:...:|.:|....||.||||||||....| |.|:|||:..:|::.:...||:  ..:
Zfish   169 KWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNR-SSSDHEATAMMKAQFMSLWDGL--DTD 230

  Fly   463 QAKVVMVLAATNFPWDIDEALRRRLEKRIYIPLPSDEGREALLKINLREVKVDDSVDLTYVANEL 527
            ....|:::.|||.|.|:|.|:.||:..|.:|..|:...|:.:||:.|....|:.:|:|:.:|.:.
Zfish   231 YNCQVIIMGATNRPQDLDSAILRRMPTRFHINQPNARQRKDILKLILENENVESAVELSEIAKQT 295

  Fly   528 KGYSGADITNVCREASMMSMRRKIAGLTPEQIRQLATEEVDLPVSNKDFNEAMSRCNKSVS 588
            .|:||:|:..:||:|:::.:|..:...:||       |:...|:..:|...|:.:..||.|
Zfish   296 DGFSGSDLREMCRDAALLCVRDFVHQESPE-------EDFIRPIRQEDLQRAIEKMKKSKS 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693
		P-loop_NTPase	325..>381	CDD:304359	27/57 (47%)
		AAA	358..496	CDD:214640	61/137 (45%)
		AAA	362..495	CDD:278434	58/132 (44%)
		Vps4_C	<570..603	CDD:286426	6/19 (32%)
atad1b	NP_001019592.1	AAA	129..258	CDD:214640	59/131 (45%)
atad1b	NP_001019592.1	AAA	133..261	CDD:278434	57/130 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593585
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840