DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kat60 and CG4701

DIOPT Version :9

Sequence 1:	NP_001262276.1	Gene:	Kat60 / 53566	FlyBaseID:	FBgn0040208	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_609721.1	Gene:	CG4701 / 34858	FlyBaseID:	FBgn0028868	Length:	384	Species:	Drosophila melanogaster

Alignment Length:	257	Identity:	100/257 - (38%)
Similarity:	153/257 - (59%)	Gaps:	8/257 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   296 RKFQPNNHIEAELVDILERDILQKDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYF---KGIRR 357
            :||:..:..|.|:: |....:..:|..:.|||||.|....:.|.|.||||:.....|   |..|.
  Fly    66 KKFRARDFNEHEMM-IASHLVTPEDIDISWSDIAGLDGTIQELRETVVLPVRHRKLFSRSKLWRA 129

  Fly   358 PWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTI 422
            | ||||:.||||.|||::|||:|.:.|..|.|:....||.|:.|||:|:...:|.:|:...|..|
  Fly   130 P-KGVLLHGPPGCGKTLIAKAIAKDAGMRFINLDVGVLTDKWYGESQKLATAVFTLAKKLQPCII 193

  Fly   423 FIDEIDSLCSRRGSESEHEASRRVKSELLVQMDGVGGGEEQAKVVMVLAATNFPWDIDEALRRRL 487
            |||||:|....||| ::|||:..:|::.::|.||:.......  |:||.|||.|.|:|:|:.||:
  Fly   194 FIDEIESFLRMRGS-NDHEATAMIKTQFMLQWDGLMSNTNIC--VLVLGATNRPQDLDKAILRRM 255

  Fly   488 EKRIYIPLPSDEGREALLKINLREVKVDDSVDLTYVANELKGYSGADITNVCREASMMSMRR 549
            ..:.:|.:|.|..|..:|::.|:..::..||:|..:|....|:||:|:..:||.|||..||:
  Fly   256 PAQFHIGVPRDCQRREILQLILQTEQLSPSVNLKELARLTIGFSGSDLRELCRHASMYRMRQ 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693
		P-loop_NTPase	325..>381	CDD:304359	30/58 (52%)
		AAA	358..496	CDD:214640	59/137 (43%)
		AAA	362..495	CDD:278434	56/132 (42%)
		Vps4_C	<570..603	CDD:286426
CG4701	NP_609721.1	Parvo_NS1	47..>152	CDD:305166	36/87 (41%)
		AAA	130..265	CDD:214640	59/138 (43%)
		AAA	133..265	CDD:278434	56/134 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467083
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840