DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kat60 and Atad1

DIOPT Version :9

Sequence 1:	NP_001262276.1	Gene:	Kat60 / 53566	FlyBaseID:	FBgn0040208	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_001030174.1	Gene:	Atad1 / 309532	RGDID:	1308570	Length:	361	Species:	Rattus norvegicus

Alignment Length:	323	Identity:	119/323 - (36%)
Similarity:	174/323 - (53%)	Gaps:	33/323 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 DPQAAQEEERKFQPNN-----------------HIEAELVDILERDILQKDPKVRWSDIADLHDA 334
            ||...|:.|.:.|...                 .|.|.|||.|       :..|.|||||.|.|.
  Rat    42 DPTRKQKVEAQKQAEKLMKQIGVKNVKLSEYEMSIAAHLVDPL-------NMHVTWSDIAGLDDV 99

  Fly   335 KRLLEEAVVLPMLMPDYFKGIR--RPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSATLTS 397
            ...|::.|:||:.....|:..|  :|.||||:.||||.|||::|||.|.|.|..|.|:..:|||.
  Rat   100 ITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTD 164

  Fly   398 KYRGESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGSESEHEASRRVKSELLVQMDGVGGGEE 462
            |:.|||:|:...:|.:|....||.||||||||....| |.|:|||:..:|::.:...||:  ..:
  Rat   165 KWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNR-SSSDHEATAMMKAQFMSLWDGL--DTD 226

  Fly   463 QAKVVMVLAATNFPWDIDEALRRRLEKRIYIPLPSDEGREALLKINLREVKVDDSVDLTYVANEL 527
            .:..|:|:.|||.|.|:|.|:.||:..|.:|..|:.:.|||:||:.|:...||..|||..||.|.
  Rat   227 HSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENVDRHVDLLEVAQET 291

  Fly   528 KGYSGADITNVCREASMMSMRRKIAGLTPEQIRQLATEEVDLPVSNKDFNEAMSRCNKSVSRA 590
            .|:||:|:..:||:|:::.:|..:...:.|.    ..|:...||..:|.:.|:.:..||...|
  Rat   292 DGFSGSDLKEMCRDAALLCVREYVNSTSEES----HDEDEIRPVQQQDLHRAIEKMKKSKDAA 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693
		P-loop_NTPase	325..>381	CDD:304359	28/57 (49%)
		AAA	358..496	CDD:214640	62/137 (45%)
		AAA	362..495	CDD:278434	59/132 (45%)
		Vps4_C	<570..603	CDD:286426	7/21 (33%)
Atad1	NP_001030174.1	RecA-like_ATAD1	92..257	CDD:410928	72/167 (43%)
Atad1	NP_001030174.1	AAA_lid_3	282..321	CDD:407720	14/38 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351773
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840