Protein Alignment Kat60 and Katnal2

DIOPT Version :10

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001419361.1
• Gene: Katnal2 / 307253
• RGDID: 1564708
• Length: 537
• Species: Rattus norvegicus
• Alignment Length: 461
• Identity: 172/461 - (37%)
• Similarity: 247/461 - (53%)
• Gaps: 79/461 - (17%)

  Fly   195 RRAAPNNRRTTPATQN--------SRPSSTIPQSTARNGPASTRNSRNSTSATAPSGGARTTNGR 251
            |....|.|.|....||        |||.:    ||.:.|  .|::.:......:      .||.:
  Rat   104 RSGGKNKRLTNDNCQNLPKIYHQKSRPKT----STVKTG--DTKSVKEHPKQES------VTNAQ 156

  Fly   252 AGGRKLSTSNTNEARDDDSTAAGNNGGAAGDGE---------------------NGDPQAAQEEE 295
            |.......:.:...:|.....|....|...|..                     |.||     .|
  Rat   157 AESSDFGLNISKIHKDSPEEKAHPRRGQIIDFRGLLTDAIKGATSEYALNTFECNPDP-----SE 216

  Fly   296 RKFQP-------NNHIEAELVDILERDILQKDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFK 353
            |..:|       |:.:. ||..::.|||...:|.::|:||..|..||:|::||||.|:..|..|.
  Rat   217 RLLKPLSAFIGMNSEMR-ELAAVVSRDIYLHNPNIKWNDIIGLDAAKQLVKEAVVYPIRYPQLFT 280

  Fly   354 GIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYA 418
            ||..||||:|:.||||||||:|||||||||.|||||:|::|:.||:||:|||:||:|||:||::|
  Rat   281 GILSPWKGLLLYGPPGTGKTLLAKAVATECKTTFFNISASTIVSKWRGDSEKLVRVLFELARYHA 345

  Fly   419 PSTIFIDEIDSLCSRRG--SESEHEASRRVKSELLVQMDGVGGGEEQAKVVMVLAATNFPWDIDE 481
            |||||:||::|:.|:||  ...|||.|.|:|:||||||||:...|:   :|.||||:|.||::|.
  Rat   346 PSTIFLDELESVMSQRGMVPGGEHEGSLRMKTELLVQMDGLARSED---LVFVLAASNLPWELDC 407

  Fly   482 ALRRRLEKRIYIPLPSDEGREALLKINLREVKVDDSVDL------TYVANELKGYSGADITNVCR 540
            |:.|||||||.:.|||.|.|:|::...|..|..:.:::|      :.::.|.:||||:||..|||
  Rat   408 AMLRRLEKRILVDLPSQEARQAMIYHWLPPVSKNHALELRTQLEYSVLSQETEGYSGSDIKLVCR 472

  Fly   541 EASMMSMRRKIAGLTPEQIR-------QLATEEVDLPVSNKDFNEAMSRCNKSVSRADLDKYEKW 598
            ||:|..:|:....|...|..       ||.|      |:.:||.:.::....|.... .::|..|
  Rat   473 EAAMRPVRKIFNVLENHQSESSNLLGIQLDT------VTTEDFLDVLAHTKPSAKNL-TERYLAW 530

  Fly   599 MREFGS 604
            ..:|.|
  Rat   531 QEKFES 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	Kp60-NTD	62..129	CDD:439297
		PHA03291	<167..>253	CDD:223033	15/65 (23%)
		SpoVK	219..566	CDD:440232	155/389 (40%)
		RecA-like_KTNA1	327..493	CDD:410930	102/167 (61%)
		Vps4_C	<570..603	CDD:462762	6/32 (19%)
Katnal2	NP_001419361.1	LisH	25..55	CDD:128913
		RPT1	184..525	CDD:440835	149/356 (42%)
		RecA-like_VPS4-like	255..419	CDD:410917	101/166 (61%)