Protein Alignment Kat60 and Fign

DIOPT Version :10

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001099954.1
• Gene: Fign / 295649
• RGDID: 1308174
• Length: 759
• Species: Rattus norvegicus
• Alignment Length: 617
• Identity: 151/617 - (24%)
• Similarity: 251/617 - (40%)
• Gaps: 170/617 - (27%)

  Fly   129 TLQDISLDLQSTKFAHKLRHQLSEESTTSKDPSAWFKPDPD------IWTPPPKDPDVWGPPKPP 187
            |:..:...|.|.::|..........:.:|:...|...|.|.      :..|||       ||.||
  Rat   172 TVPSLHAGLPSQEYAPGYNGSYLHSTYSSQPTPALPSPHPSPLHSSGLLQPPP-------PPPPP 229

  Fly   188 PTTQAVGRRAAPNNRRTTPATQNSRPSSTIPQSTARNGPASTRNSRNSTSATAPSG--------- 243
            |.       ..|....|:..:..|.||::.|..||.....|...:....||..|||
  Rat   230 PA-------LVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPP 287

  Fly   244 -----------------GARTTNGRAG------------------------GRKLSTSNTNEARD 267
                             .:..||..|.                        |::.||.:......
  Rat   288 TTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMP 352

  Fly   268 DDSTAAGNNGGAAGDGENGDPQA----------AQEEERKFQ----------------------- 299
            |:|.:..|.|.  |...|.:..:          ..|::|||.
  Rat   353 DNSISNSNRGN--GFDRNAETSSLAFKPTKQLMPSEQQRKFSSQSSRALTPPSYSTAKNSLGSRS 415

  Fly   300 ------------------------------------PNNH--------IEAELVDILERDILQKD 320
                                                .:||        .:..|:|::..:|:.:.
  Rat   416 SESFGKYTSPVMSEHGDDHRQLLAHPIQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQG 480

  Fly   321 PKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGT 385
            |.|.|||||.|...|.:::|.|:.|:|..|.|.|:....:.:|:.||.|||||:|.:.:|::.|.
  Rat   481 PPVDWSDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGA 545

  Fly   386 TFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGSESEHEASRRVKSEL 450
            |||.::.:.|.:|:.||:||::...|.:||...||.||:.:||.|.|.:.|| ||....|:::|.
  Rat   546 TFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVSE-EHSPVSRMRTEF 609

  Fly   451 LVQMDGV-GGGEEQAKVVMVLAATNFPWDIDEALRRRLEKRIYIPLPSDEGREALL--KINLREV 512
            |:|:|.| ...|:|   ::|:.||:.|.:|||:|||...||:.||||....|..::  .::....
  Rat   610 LMQLDTVLTSAEDQ---IVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNY 671

  Fly   513 KVDDSVDLTYVANELKGYSGADITNVCREASMMSMR----RKIAGLTPEQIRQLATEEVDLPVSN 573
            .::|. :...:....:|:||.|:.::|:||::..:.    ..::.:.|.|:|         |::.
  Rat   672 CLNDK-EFALLVQRTEGFSGLDVAHLCQEAAVGPLHAMPATDLSAIMPSQLR---------PITY 726

  Fly   574 KDFNEAMSRCNKSVSRADLDKYEKWMREFGSS 605
            :||..|..:...|:|:.:||.|.:|.:.||.|
  Rat   727 QDFENAFCKIQPSISQKELDMYVEWNKMFGCS 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	Kp60-NTD	62..129	CDD:439297	151/617 (24%)
		PHA03291	<167..>253	CDD:223033	25/117 (21%)
		SpoVK	219..566	CDD:440232	116/480 (24%)
		RecA-like_KTNA1	327..493	CDD:410930	67/166 (40%)
		Vps4_C	<570..603	CDD:462762	10/32 (31%)
Fign	NP_001099954.1	RecA-like_fidgetin	487..650	CDD:410931	67/166 (40%)
		AAA_lid_3	675..>706	CDD:465537	8/31 (26%)
		Vps4_C	<723..756	CDD:462762	10/32 (31%)