Protein Alignment Kat60 and Katna1

DIOPT Version :10

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001004217.2
• Gene: Katna1 / 292464
• RGDID: 1303062
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 546
• Identity: 283/546 - (51%)
• Similarity: 363/546 - (66%)
• Gaps: 65/546 - (11%)

  Fly    63 ICENAKLARDMALTGNYDSACIYYEGLQGLLARQLKATADPLRKGKWSMINQQISQEHAKIKAIQ 127
            |.||.||||:.||.||||||.:||:|:...:.:.|.:..|.....||..:.|:|:.|...:|.|.
  Rat     8 ITENVKLAREYALLGNYDSAMVYYQGVLDQINKYLYSVKDTHLHQKWQQVWQEINVEAKHVKEIM 72

  Fly   128 RTLQDISLDLQSTKFAHKLRHQLSEESTTSKDPSAWFKPDPDIWTPPPKDPDVWGPPKPPPTTQA 192
            :||:...||..|.|.|   :|:|                       |..:.:||..|.|
  Rat    73 KTLESFKLDSTSLKAA---QHEL-----------------------PSSEGEVWSLPVP------ 105

  Fly   193 VGRRAAPNNRRTTPATQNSRPSSTIPQSTARNGPASTRNSRNSTSATAPSGGARTTNGRAGGRKL 257
            |.||..|..|: ..:||:|.|.   |.|   |.|.:...:...::.:..|...:....|
  Rat   106 VERRPLPGPRK-RQSTQHSDPK---PHS---NRPGAVVRAHRPSAQSLHSDRGKAVRSR------ 157

  Fly   258 STSNTNEARDDDSTAAGNNGGAAGDGENGDPQAAQE-EERKFQPNNHIEAELVDILERDILQKDP 321
            .....::.|::               :|..|.|..| |..||....: :.:||:.|||||:.::|
  Rat   158 EKKEQSKGREE---------------KNKLPAAVTEPEANKFDSTGY-DKDLVEALERDIISQNP 206

  Fly   322 KVRWSDIADLHDAKRLLEEAVVLPMLMPDYFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTT 386
            .|||.|||||.:||:||:|||||||.||::||||||||||||||||||||||:|||||||||.||
  Rat   207 NVRWYDIADLVEAKKLLQEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECKTT 271

  Fly   387 FFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGSESEHEASRRVKSELL 451
            ||||||:||||||||||||:|||||||||||:|:|||||||||:|||||:..|||||||||:|||
  Rat   272 FFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELL 336

  Fly   452 VQMDGVGGGEEQ---AKVVMVLAATNFPWDIDEALRRRLEKRIYIPLPSDEGREALLKINLREVK 513
            ||||||||..|.   :|:|||||||||||||||||||||||||||||||.:|||.||:|:|||::
  Rat   337 VQMDGVGGASENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPSAKGREELLRISLRELE 401

  Fly   514 VDDSVDLTYVANELKGYSGADITNVCREASMMSMRRKIAGLTPEQIRQLATEEVDLPVSNKDFNE 578
            :.|.|:|..:|..::||||||||||||:||:|:|||:|.|||||:||.|:.||:.:|.:.:||..
  Rat   402 LADDVNLASIAENMEGYSGADITNVCRDASLMAMRRRIEGLTPEEIRNLSREEMHMPTTMEDFEM 466

  Fly   579 AMSRCNKSVSRADLDKYEKWMREFGS 604
            |:.:.:||||.||:::||||:.||||
  Rat   467 ALKKVSKSVSAADIERYEKWIVEFGS 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	Kp60-NTD	62..129	CDD:439297	27/65 (42%)
		PHA03291	<167..>253	CDD:223033	20/85 (24%)
		SpoVK	219..566	CDD:440232	212/350 (61%)
		RecA-like_KTNA1	327..493	CDD:410930	142/168 (85%)
		Vps4_C	<570..603	CDD:462762	15/32 (47%)
Katna1	NP_001004217.2	Kp60-NTD	7..74	CDD:439297	27/65 (42%)
		RPT1	134..474	CDD:440835	215/361 (60%)
		RecA-like_KTNA1	212..381	CDD:410930	142/168 (85%)