DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Kat60 and Gykl1

DIOPT Version :9

Sequence 1:	NP_001262276.1	Gene:	Kat60 / 53566	FlyBaseID:	FBgn0040208	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_034423.2	Gene:	Gykl1 / 14625	MGIID:	891990	Length:	549	Species:	Mus musculus

Alignment Length:	117	Identity:	27/117 - (23%)
Similarity:	46/117 - (39%)	Gaps:	32/117 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SSALIGTNLCLSFLATMTTTCSDRQLLRGGKQKTTTCVGMTVMAKTTFEEICENAKLARDMALTG 77
            |:||:| .||                |:.|:.|:|...|..::..|  .:.|.|::  ..:..|.
Mouse   261 SAALVG-QLC----------------LQDGQAKSTYGTGCFLLCNT--GQKCVNSE--HGLLTTV 304

  Fly    78 NYD---SACIYYEGLQGLLARQLKATADPLRKGKWSMINQQISQEHAKIKAI 126
            .|.   ...:|| .|:|.:|......:       |...|.||.|..::|:.:
Mouse   305 AYQLGRQEPVYY-ALEGSVAIAGAVVS-------WIKNNLQIIQSSSEIEKL 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693
		P-loop_NTPase	325..>381	CDD:304359
		AAA	358..496	CDD:214640
		AAA	362..495	CDD:278434
		Vps4_C	<570..603	CDD:286426
Gykl1	NP_034423.2	glycerol_kin	11..513	CDD:273549	27/117 (23%)
Gykl1	NP_034423.2	FGGY_GK1-3_metazoa	11..513	CDD:212664	27/117 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900