Protein Alignment Kat60 and spas

DIOPT Version :10

• Sequence 1: NP_001262276.1
• Gene: Kat60 / 53566
• FlyBaseID: FBgn0040208
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_061504441.1
• Gene: spas / 1273633
• VectorBaseID: AGAMI1_003042
• Length: 888
• Species: Anopheles gambiae
• Alignment Length: 675
• Identity: 217/675 - (32%)
• Similarity: 307/675 - (45%)
• Gaps: 171/675 - (25%)

  Fly    19 TNLC-----LSFLATMTTTCSDRQLLRG---GKQKTTTCVGMTVMAKTTF---EEICENAKLARD 72
            |||.     |.||..| ......:||.|   |:|........||..:.||   :|....|..:..
Mosquito   291 TNLSMARDRLQFLELM-LEAKRLELLEGSEQGEQTHKQPSHSTVRRQNTFTVGDEDTSTALSSAK 354

  Fly    73 MALTGNYDSACIYYEGLQGLLARQLKATADPLRKGKWSM-INQQISQEHAKIKAIQRTL--QDIS 134
            .|.:|...||                    |.||.|..| |...:.:..:..::...||  :|:.
Mosquito   355 AATSGGAASA--------------------PERKFKLPMFIPSDLHETGSGTRSPTTTLPYRDVK 399

  Fly   135 LDLQSTKFAHKLRHQLSEESTTSKDPSAWFKPDPDIWTPPPKDPDVWGPPKPPPTTQAVGRRAAP 199
            ..|.||...::: ...:|..|.:                               |.....|..|.
Mosquito   400 SKLHSTPTENRM-VSFNENCTIT-------------------------------TNHHPARGTAA 432

  Fly   200 NNRRTTPATQNSRPSSTIPQSTARNGPASTRNSRNST--------------SATAP--SGGARTT 248
            ::|.||.||..:.||..|.|:      ||..:.|..|              |.|.|  .||.|||
Mosquito   433 SSRPTTAATAPATPSLPIKQT------ASEASGRKLTVGYKRPGNLGVMNKSQTLPRSMGGTRTT 491

  Fly   249 ---NGRAGGRKLSTSNTNEARDDDSTAAGN--NGGAA---------------------------- 280
               .|.|||......|       ..|..|:  .|||.
Mosquito   492 PTGTGGAGGIAGGLGN-------GGTYGGSIVGGGAGMPKIVPKPAATPPAIRRQFSIPGSSPVR 549

  Fly   281 ----GDGENGDP-----------QAAQEEERKFQPN---NHIEAELVDILERDILQKDPKVRWSD 327
                |.|....|           |..|.::::.||.   ..:|.:||.|:..:|::...||:|.|
Mosquito   550 KASNGYGSKNTPPPRSKTPLAGQQPQQPQQQQQQPQISVKGVEPKLVQIIMDEIVEGGAKVQWQD 614

  Fly   328 IADLHDAKRLLEEAVVLPMLMPDYFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSS 392
            ||....||:.|:|.|:||.:.|:.|.|:|.|.||:|:.||||.|||:||:||||||..|||::|:
Mosquito   615 IAGQEVAKQALQEMVILPSVRPELFTGLRTPAKGLLLFGPPGNGKTLLARAVATECSATFFSISA 679

  Fly   393 ATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGSESEHEASRRVKSELLVQMDGV 457
            |||||||.|:.||:||.||.:||...||.|||||:||:.|.| |.:||||:||:|:|.|||.||:
Mosquito   680 ATLTSKYVGDGEKLVRALFAVARELQPSIIFIDEVDSVLSER-SSNEHEATRRLKTEFLVQFDGL 743

  Fly   458 GGGEEQAKVVMVLAATNFPWDIDEALRRRLEKRIYIPLPSDEGREALLKINLRE--VKVDDSVDL 520
            ....|..::| |:||||.|.::|||..||..||:|:.||..:.||.||:..|::  ..:.|: ||
Mosquito   744 PANSEADRIV-VMAATNRPQELDEAALRRFPKRVYVTLPDRDTRELLLRRLLQKQGSPLSDA-DL 806

  Fly   521 TYVANELKGYSGADITNVCREASMMSMRRKIAGLTPEQIRQLATEEVD-------LPVSNKDFNE 578
            .::|...:||||:|:|.:.|:|::            |.||:|..|||.       ..:...||:.
Mosquito   807 AHLAQLTEGYSGSDLTALARDAAL------------EPIRELNVEEVKNMDPTKLRSIRESDFHN 859

  Fly   579 AMSRCNKSVSRADLDKYEKWMREFG 603
            ::.|..:||:...|..||||:::||
Mosquito   860 SLKRIRRSVAPQSLAAYEKWLQDFG 884

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kat60	NP_001262276.1	Kp60-NTD	62..129	CDD:439297	12/67 (18%)
		PHA03291	<167..>253	CDD:223033	25/104 (24%)
		SpoVK	219..566	CDD:440232	155/415 (37%)
		RecA-like_KTNA1	327..493	CDD:410930	93/165 (56%)
		Vps4_C	<570..603	CDD:462762	10/32 (31%)
spas	XP_061504441.1	None