Protein Alignment bor and Atad3a

DIOPT Version :10

• Sequence 1: NP_524996.1
• Gene: bor / 53565
• FlyBaseID: FBgn0287225
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_849534.2
• Gene: Atad3a / 108888
• MGIID: 1919214
• Length: 591
• Species: Mus musculus
• Alignment Length: 604
• Identity: 371/604 - (61%)
• Similarity: 456/604 - (75%)
• Gaps: 28/604 - (4%)

  Fly     1 MSWLLGRNRQQ--------PQPDQTAGFSEGGGAADPEGRTAGEKSGDSQLSRAERKAMEAYRFD 57
            ||||.|....:        |.|....| :||||     .|.||::.....         :...||
Mouse     1 MSWLFGIKGPKGEGTGPPLPLPPAQPG-AEGGG-----DRGAGDRPSPKD---------KWSNFD 50

  Fly    58 SSALERAADAAKTLERSKHAREALELSKMQEATRQTEYNTKVKEYEAHIEQAKVEQKRIDHEERR 122
            .:.|||||.||:.||.|:||:|||.|::|||.|.|.|..:|:|||||.:||.|.||.|:..||||
Mouse    51 PTGLERAAKAARELEHSRHAKEALSLAQMQEQTLQLEQQSKLKEYEAAVEQLKSEQIRVQAEERR 115

  Fly   123 KTLIEETKQQQQRAQYQDQLSRKRYEDQLLQQQRVQEENLRKQEESVQRQEAMRRQTIEHEIEMK 187
            |||.|||:|.|.||||||:|:|:||||||.|||.:.||||||||||||:|||:||.|:|.|:|::
Mouse   116 KTLTEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAIRRATVEREMELR 180

  Fly   188 EKNRLKLLEHELRAKARVDRENRDINLEKIRLKAQEHRTTVLEGIKTAGTVIGAGAEAMLTDWDK 252
            .||.:..:|.|.||:|:.||||.||..|:|||||.|||.|:||.|:||||::|.|..|.:|||||
Mouse   181 HKNEMLRVEAEARARAKADRENADIIREQIRLKAAEHRQTILESIRTAGTLLGEGFRAFVTDWDK 245

  Fly   253 VLTAAGGLSLLALGVYTAKGATGVVSRYVEARIGKPTLVGETSRFAFLDALKNPLHYLKRLRAKP 317
            |.....||:|||:|||:||.||.|..||:|||:|||:||.||||.:.|:||::|:...:||.::|
Mouse   246 VTATVAGLTLLAVGVYSAKNATSVAGRYIEARLGKPSLVRETSRISVLEALRHPIQVSRRLVSRP 310

  Fly   318 TDALQGVVLNPKLEERLRDIAIATKNTRINKGMYRNVLMHGPPGTGKTMFAKKLAEHSGMDFAIM 382
            .|||:||:|:|.||.|:|||||||:||:.||.:||||||:||||||||:||||||.|||||:|||
Mouse   311 QDALEGVILSPSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIM 375

  Fly   383 TGGDVAPMGKEGVTAIHKVFDWSHTSRRGLLLFVDEADAFLRKRSSEKISEDLRAALNAFLYRTS 447
            |||||||||:|||||:||||||:.||||||||||||||||||||::|||||||||.|||||:||.
Mouse   376 TGGDVAPMGREGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTG 440

  Fly   448 EQNPKFMLVLASNTPEQFDYAINDRLDEMVEFTLPGLEERERLLRLYFDKYVLQPAAAGAKRFKL 512
            :.:.|||||||||.|||||:|||||:||||.|.||..||||||:|:|||||||:||..|.:|.|:
Mouse   441 QHSSKFMLVLASNQPEQFDWAINDRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLKV 505

  Fly   513 DTFDYGKTCSKMAALCEGMSGREISKLGVSWQAAVYASEDGLLTEKMVLDRCYSAAQQHKQKMAW 577
            ..|||||.||::|.|.||||||||::|.|:|||..|:||||:|||.|:..|...|.|||:|||.|
Mouse   506 AQFDYGKKCSEVAQLTEGMSGREIAQLAVAWQAMAYSSEDGVLTEAMMDARVQDAVQQHQQKMQW 570

  Fly   578 LSDQERADHKSITGTAAPP 596
            |. .||.|.:    |..||
Mouse   571 LK-VERPDSQ----TNKPP 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bor	NP_524996.1	ATAD3_N	35..291	CDD:463442	147/255 (58%)
		RecA-like_ATAD3-like	330..479	CDD:410920	121/148 (82%)
Atad3a	NP_849534.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		17/65 (26%)
		Required for interaction with the inner surface of the mitochondrial outer membrane. /evidence=ECO:0000250|UniProtKB:Q9NVI7	2..49		14/61 (23%)
		ATAD3_N	42..285	CDD:463442	147/251 (59%)
		S100B-binding. /evidence=ECO:0000250|UniProtKB:Q9NVI7	289..304		5/14 (36%)
		RecA-like_ATAD3-like	323..472	CDD:410920	121/148 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	572..591		6/18 (33%)