Protein Alignment gukh and nhsl2

DIOPT Version :9

• Sequence 1: NP_732393.1
• Gene: gukh / 53563
• FlyBaseID: FBgn0026239
• Length: 1788
• Species: Drosophila melanogaster
• Sequence 2: XP_009301724.1
• Gene: nhsl2 / 794153
• ZFINID: ZDB-GENE-130530-951
• Length: 1282
• Species: Danio rerio
• Alignment Length: 1773
• Identity: 333/1773 - (18%)
• Similarity: 534/1773 - (30%)
• Gaps: 683/1773 - (38%)

  Fly   142 ISNITLSNALRQLASLVLIASDIFDDLQRDLQAVGERAGRVQRKIAAVERRVCAYDPKTVTVPES 206
            :..:||...||||:.|...:..|.::|:.:|.::..|:|.::.|:.::::.:.|...|......:
Zfish    27 VCGLTLCAVLRQLSDLSRQSVSILEELEGELASICYRSGALENKLTSLQKHIAALATKPPAKTAT 91

  Fly   207 DLLTFAQRKHHFETDKSFQQ--ELFTGETRPLSVRQLYTEAGKELPVATGATATALASLAHSQSL 269
            :|.:.::|..||::  |:||  .:|...:||..|::|:.||
Zfish    92 NLDSESKRTAHFQS--SWQQHVNVFGSWSRPECVQELHQEA------------------------ 130

  Fly   270 IPSRSISFNGEVLSSDHEVLQLNGSTDTEDHLLCVSDFGNANRKLRTRIDAEIEIRLPAAIEDLR 334
                                |||                                 |.:.::|.
Zfish   131 --------------------QLN---------------------------------LQSLLQDF- 141

  Fly   335 KWTSSEALGDVTVTPDCMHHVDTSVSTSLAIGENGILTPALSPSVLSADAVDALYAQNLSQAADS 399
                .|.|.|..||.....|..:..|      |:...|.:.|||.|:....:.::.....|..:.
Zfish   142 ----EEQLYDNRVTGQTFKHPSSQSS------EDTSTTLSRSPSSLNNKKTEFVFVPANKQVCED 196

  Fly   400 SRHNHHTQALIPNDINKDVPL---NHRLPSP--EEQTKQIALKYPAEVISVNTSGKHFQRMCAAR 459
            .......:|..|:....:..|   |..|..|  |:....:..:.||:::.:..:|:.|.:. |||
Zfish   197 ETTTLGVRAQDPSPCASEKTLLGWNAALSPPVAEKPRWYLGRQTPAQLVPIEITGQSFDKH-AAR 260

  Fly   460 KSTSGGYAGGATAGSSSSTSPENAGQTEGNNLDDNVQTVSRRSRSRKVRGKRRNTIAGIDQKEIQ 524
            .|..     .||..:.|:.:|:..                ||.||         .:||.|.
Zfish   261 HSEL-----RATIRTDSAVNPKTI----------------RRPRS---------VVAGPDV---- 291

  Fly   525 DAANGNGESKNASNATSPVAPAQQAETTSSDAKKSKKFGRSKSSDILKKESAALPYDKGKSTLTR 589
             ..:..|:||
Zfish   292 -TLHCQGDSK------------------------------------------------------- 300

  Fly   590 LNSLKQWGRNRFKFMHRTGELGDQLDTSGCSSQNSSAEKADSHHGSPAGDNSKRDIDDECVVHHL 654
                               .|...|....||..:|.....:     |..:|:.:        .|:
Zfish   301 -------------------ILAVDLIQGACSPGSSQPRSLE-----PTTENTGQ--------QHI 333

  Fly   655 VAQKSESRFSHERKPSYSSSEKSISVSSSGQLRGRLQLSSGPMAAAHVKMRETATLNRQRRNGLH 719
            ..:|::|...:...||..:                   .||        |.:.|||
Zfish   334 PLRKTQSDLEYSIPPSPKT-------------------PSG--------MMDHATL--------- 362

  Fly   720 ALAGKEEQPHSSSGNW-----SASSESGRASIGSEITMQPKSSASSTSLNVSSFQPGGAGSG--P 777
                     ...|.:|     |..|.|...|....:...|.|....|...:  ..|||...|  .
Zfish   363 ---------MCPSPSWNGPKGSTFSPSWNDSYNYALVTSPASKQPVTKTGM--LTPGGDRGGLIC 416

  Fly   778 PSSMLSRRRFLNTSASSSVTSEGTATPELQAEAGAYPGHLDDETSSAYSCDTEGYYTSFHMDSGL 842
            ||...|.....:.|.|||.||.....           ||      ..|:..|:|        ||:
Zfish   417 PSQTSSGLSMSSGSHSSSFTSISEPC-----------GH------RVYTVSTQG--------SGV 456

  Fly   843 RTLKEEEPSVMPGTPLQTSLHTSSYSFGSQSNQTVLNAESEYELFGRGSTSTTTSSAGTVCTA-- 905
            .|.|..|..|...|.:..:         |:|.|...:|.|....|...|.||.|.| |:.|:|
Zfish   457 VTGKRNETEVTASTAVTRN---------SKSEQEKRSARSNVFRFRERSLSTPTDS-GSFCSADN 511

  Fly   906 LMSGAASGPDVPERSSSLGKHSGQSRSQSTSASSSTLERSYSSSTIGSTLERTGTIK---RNVKM 967
            :.|...:...|||..|....:...|...|||..:       .|.|.||.....|.::   |::.:
Zfish   512 ICSPGEAVSGVPEGESYALLYPSNSSEDSTSTDN-------VSVTTGSDFLPDGRLRSRSRSISL 569

  Fly   968 SPTKAGGEVTEKDDQQDQDQQQQLEFSE-----SSDLEGVERIERIKQKTALTSKRI-----PSM 1022
            ..:|      :|.....:........||     |...||..|..|  .|:....:.|     |..
Zfish   570 KKSK------KKPPPPVRSVSLMKNLSEIRGMGSYQNEGHFRDGR--PKSLFIPRDIQDSFQPEF 626

  Fly  1023 CIITPTTSDDDEHQTNDPNRTLTSLTIDVEHGEQDEDEAEQKTPTNSKDH-NLNELKQT--PTKA 1084
            .|..|   |||..|.:....|.:.::          ..|:::|......| .|||.|..  |.::
Zfish   627 LIAKP---DDDTDQAHSSLETSSDIS----------QPADRETELGFPPHWQLNEWKSNNDPYRS 678

  Fly  1085 LSGMFEKLRVKLVPGKSSPAKNQMQPKPANSSAVNDDELYDLAGEYVTIADISNNNNNNKNIGRR 1149
            |||                          :|:|..           .|:.:......:::::.
Zfish   679 LSG--------------------------SSTATG-----------TTVIECMKVRGSSESLN-- 704

  Fly  1150 NTGMGIYYSNDIVSKRVEPSTSAVSEYVSLNELPQHLRRHAVSSRSAPAAESESCAQQQLPVEPA 1214
                             .||||                            .:.|.:|..:..|..
Zfish   705 -----------------SPSTS----------------------------RATSPSQMSIEAETK 724

  Fly  1215 AATSQPPPL--PLGGRTQGVGDGVPMYAEIGELSEEKPLASAANRRLR-PNAEGKLVYDSDSLKR 1276
            .:..:||.|  |..|.:.               ..|.|..:.:|..|. |:..|        .|.
Zfish   725 VSPFKPPCLLSPSSGYSS---------------QSETPTPTISNTLLTGPSPVG--------CKM 766

  Fly  1277 RKGAHTTFAPGPYVKETESALHSAESAAAAIASSQDPSAASGAISSTKSAKLLLLTSGGLISGNR 1341
            |          |.:.|.:|:|.         ||::|.|.:..:.....:|:|
Zfish   767 R----------PKIPERKSSLP---------ASAKDKSRSRLSFELPANAQL------------- 799

  Fly  1342 KVANVRPIVAKSPLSRNVSEMATYQATSYQDQKQLLANRTNPFYETIAAPVANLMMPSPSGKSNS 1406
            .::.|:|   |...||..|:.:|             ||:...            :.||.|.....
Zfish   800 DLSFVKP---KPKASRRHSDTST-------------ANKPGK------------LSPSQSSLPMV 836

  Fly  1407 STGSTATSSSSSASGQSGEEGYQRFSNIYEQVQ---------PAPSTQPQEDATATPFQRSAPIY 1462
            :|.........|.|....|:.....|:|.|:.|         |:.:.||:......|.....|:.
Zfish   837 TTTDLRNIRLRSVSRSELEDSPDGSSDIIEEEQSRDLSPPITPSNTKQPKPPVAMKPPLPKRPVN 901

  Fly  1463 WTLQNRRSQP------------RPQPAGNVTCRDDLYATPIRRADRLPRPVAAAAATAA----EG 1511
            .||::..|.|            ||.|.||:..        :.|..:..||..|:.:|:|    |.
Zfish   902 LTLKSPSSSPLTPESPPSSPVDRPMPVGNIYM--------VVRKPKPKRPAQASLSTSAIATQEP 958

  Fly  1512 NRSNI-------------------SPIVP-RNRSGAFLTSTPTRSGEGERDSENTQLPP--MKQP 1554
            .||::                   ||..| |......|.|..|.|...|.|....::||  .|:|
Zfish   959 IRSHVSTFPEFDLEHGIPIEEDLPSPSSPEREDKCKTLPSRMTISCLAELDKRKPKVPPPVPKKP 1023

  Fly  1555 SRNWTDDAPERLNTCADRIGQSKTTLMDFKKLLLAKSAKASPVQRKVSAVE--LLKKPAQ----- 1612
            |.........:.|..|:|            :.||::|...||.....|.:|  |||...:
Zfish  1024 SVLLLPSPSIQTNGGAER------------QTLLSESISQSPTGTSASEIEGDLLKDEEEDYSAK 1076

  Fly  1613 ---------------------------------------ATATPP--VVKPSGPGQKV----ASA 1632
                                                   ...|||  :||......::    .||
Zfish  1077 QISHENHQIPELYETFGNEENDVVVEEYSSEDRGSHHFMERETPPAEIVKEIYTETEILEENISA 1141

  Fly  1633 GSK-----------------PTINTSLKLLDLSGSPKTFANRRMLRQGQFGSPSKTFAPKMRGPV 1680
            ..|                 ||.:|:..|..:....|    |::|.:.:   ||.:|. :.:..|
Zfish  1142 VDKTELHITEETEDEVFVNTPTTHTTEDLFTIIHRSK----RKVLGRKE---PSDSFG-RSQCLV 1198

  Fly  1681 NMVAAAAAPPRTDIMSTTIPEANSEEDH---------SNTSGGSRASSEAGETVPSSFDLKRNF- 1735
            :.|.:::...||..:.|| |.::|..::         |..|.|:|.|  |.|.:.|:..|.|..
Zfish  1199 SPVKSSSTDFRTLGLGTT-PRSSSRNENFMALLQKRSSKASSGTRVS--AMELLKSTNPLARRVT 1260

  Fly  1736 -FLQTEENNFMRGELKPS 1752
             |.|::.:.......|||
Zfish  1261 EFSQSQPDGSAMNTPKPS 1278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gukh	NP_732393.1	NHS	<818..>846	CDD:291922	6/27 (22%)
nhsl2	XP_009301724.1	NHS	<638..774	CDD:291922	37/262 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000