DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gukh and wasf3

DIOPT Version :9

Sequence 1:	NP_732393.1	Gene:	gukh / 53563	FlyBaseID:	FBgn0026239	Length:	1788	Species:	Drosophila melanogaster
Sequence 2:	NP_001072263.1	Gene:	wasf3 / 779716	XenbaseID:	XB-GENE-1013965	Length:	502	Species:	Xenopus tropicalis

Alignment Length:	548	Identity:	103/548 - (18%)
Similarity:	169/548 - (30%)	Gaps:	186/548 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 EFDSISNITLSNALRQLASLVLIASDIFDDLQRDLQAVGERAGRVQRKIAAVERRVCAYDPKTVT 202
            |.:.::|.||:..:|||:||...|.|||.:|..:......||..:|.:|..:..:|...|.   |
Frog    25 ELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEANNFYIRANSLQDRIDRLAVKVTQLDS---T 86

  Fly   203 VPESDLLTFAQRKHHFETDKSFQQELFTGETRPLSVRQLYTEAGKELPV---------------- 251
            |.|..|.....|| .|::..:..|::.:..:.|..|..:|....:..|:
Frog    87 VEEVSLQDINMRK-AFKSSTTQDQQVVSKNSIPKPVIDIYRTCDRPPPLDILSAYRDDKKDSLKF 150

  Fly   252 ----------------------------------ATGATATALA------------SLAHSQSLI 270
                                              ..|.|.....            .:|:.:.|.
Frog   151 YTDPSYFFDLWKEKMLQDTEDKRKEKRRQKEQKRVDGTTREVKKVRKARNRRQEWNIMAYDKELR 215

  Fly   271 PSRSISFN-GEVLSSDHEVLQLNGSTDTEDHLLCVSDFGNANRKLRTRIDAEIEIRLPAAIEDLR 334
            |...:|.| .:|.||:..:     |.||..|:..::::.                 .||
Frog   216 PDNRLSPNVFQVASSEGSL-----SPDTRSHISDITEYS-----------------YPA------ 252

  Fly   335 KWTSSEALGDVTVTP------DCMHHVDTSVSTS----LAIG--ENGILTPALSPSVLSADAVDA 387
              |.:.::....:||      |..||:.||.:..    .|.|  .:|.|:....|.......||.
Frog   253 --TPNHSIHHHPMTPTYMGSVDPQHHIGTSQTNDHDYRSASGTLRHGTLSRPQQPPPPPPAGVDG 315

  Fly   388 LYAQNLSQAADSSRHNHHTQAL--------------IPNDINKDV-PLNHRLP-SPEEQTKQIAL 436
            .....:..|..|.|.....|.:              ||:.....| ||.|.|| ||..|..  ..
Frog   316 TSPVPIVSANGSLRRVLPPQMMEYYPTGSPPPPPPVIPSAQTAFVSPLQHSLPSSPAAQMS--GS 378

  Fly   437 KY-------------------------PAEVISVNTSGKHFQRMCAARKSTSGGYAGGATAGSSS 476
            .|                         ||...|:.:|..||.|:..| |...|....|.|:.:.|
Frog   379 TYAPSPPPGGIINLLASPGPPPPPPGPPAFAQSLASSPMHFARVLEA-KRLDGAQLLGLTSDARS 442

  Fly   477 STSPENAGQTEGNNLDDNVQTVSRRSRSRKVRGKRRNTIAGIDQKEIQDAANGNGESKNASNATS 541
                            |.:..:.                .||..|::|:......:.:...|..:
Frog   443 ----------------DLLSAIR----------------MGIQLKKVQEQREQEAKREPVGNDVA 475

  Fly   542 PVAPAQQAETTSSDAKKSKKFGRSKSSD 569
            .:. :::.....||::...:|..:..||
Frog   476 TIL-SRRIAVEYSDSEDESEFDENDWSD 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gukh	NP_732393.1	NHS	<818..>846	CDD:291922
wasf3	NP_001072263.1	WH2_WAVE-3	437..502	CDD:409216	11/97 (11%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12902
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010