DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gukh and si:ch73-362m14.4

DIOPT Version :9

Sequence 1:	NP_732393.1	Gene:	gukh / 53563	FlyBaseID:	FBgn0026239	Length:	1788	Species:	Drosophila melanogaster
Sequence 2:	XP_003200954.1	Gene:	si:ch73-362m14.4 / 555437	ZFINID:	ZDB-GENE-120215-30	Length:	501	Species:	Danio rerio

Alignment Length:	532	Identity:	100/532 - (18%)
Similarity:	176/532 - (33%)	Gaps:	133/532 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  1075 NELKQTPTKALSGMFEKLRVKLVPGKSSPAKNQMQPKPANSSAVNDDELYDLAGEYVTIADISNN 1139
            |||:......|:.:     :|.:.|.|..|:                   |:.||..
Zfish    24 NELECVTNSTLAAI-----IKQLGGLSRHAE-------------------DIFGELF-------- 56

  Fly  1140 NNNNKNIGRRNTGMGIYYSNDIVSKRVEPSTSAVSEYVSLNELPQHLRRHAVSSRSAPAAESESC 1204
            |..|....|.|:   :....|:::.:|....|.|.| |||.::  ::|:   :.:|:...:.:..
Zfish    57 NEANSFYMRMNS---LQERVDLLAVKVTQLDSTVEE-VSLQDI--NMRK---AFKSSTIQDQQVV 112

  Fly  1205 AQQQLP---VEPAAATSQPPPLP-LGGRTQGVGDGVPMYAE---IGELSEEKPLASAANRR---L 1259
            ::..:|   :|......:||||. |........||:..|.:   ...|.:||.|.:..|:|   .
Zfish   113 SRNSIPNPVMEVYQRCDKPPPLNILTPYRDDKKDGLKFYTDPSYFFNLWKEKMLQATENKRKEKR 177

  Fly  1260 RPNAEGKLVYD--SDSLKRRKGAH-----------------TTFAPGPY--------VKETESAL 1297
            |...|.|...|  .:..|.||..:                 |...|.||        :....|.:
Zfish   178 RQKQEQKHTEDPTREVKKVRKARNRRQEWNMMAYDKEFRPDTRLTPSPYHGMSSEGSLSPDRSGM 242

  Fly  1298 HSAESAAAAIASSQD-----PSAASGAISSTKS---AKLLLLTSGGLISGNRKVANVRPIVAKSP 1354
            ....|..|:....|:     |....|..:.|:|   |....::|....:....:..|:|.....|
Zfish   243 SDEHSYPASPNHPQEVGGVGPDGKDGGPTQTQSLDRAYRPAVSSSAASARQHSLGRVQPHHGPPP 307

  Fly  1355 LSRNVSEMATYQATSYQDQKQLLANRTNPFYETIAAPVANLMMPSPSGKSNSSTGSTATSSSSSA 1419
            ...:::......|..|.      .::.:..:...|.|....::||.....:|::|..:.:..:.|
Zfish   308 ADSSLNGPRPAAAKDYS------GHQMHEHFIPPAPPPPPPLIPSSQTAFDSTSGPPSLAPGTMA 366

  Fly  1420 SGQSGEEGYQRFSNIYEQVQPAPSTQPQEDATATP---FQRSAPIYWTLQNRRSQPRPQPAGNVT 1481
            |              .....|:|...|....||:|   .....|:         .|.|.|.|..|
Zfish   367 S--------------LRPYSPSPPPAPPSGYTASPAHAVMGGPPV---------APPPPPPGPPT 408

  Fly  1482 CRDDLYATPIRRADRLPRPVAAAAATA-AEGNRSNISPIVPRNRSGAFLTSTPTRSGEGERDSEN 1545
                          ..|.|..||..:. :...|....|::|.:.:.:.|.:...|..:..:..|.
Zfish   409 --------------HAPSPSRAAHPSGDSTLQRKGPVPLIPMSDARSDLLAAIRRGIQLRKVQEQ 459

  Fly  1546 TQLPPMKQPSRN 1557
            .:....|:|..|
Zfish   460 REQEAKKEPVGN 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gukh	NP_732393.1	NHS	<818..>846	CDD:291922
si:ch73-362m14.4	XP_003200954.1	DUF948	<30..130	CDD:295114	24/140 (17%)
		DUF4482	162..>247	CDD:291484	17/84 (20%)
		WH2	437..463	CDD:280384	3/25 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12902
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010