Protein Alignment gukh and WASF2

DIOPT Version :10

• Sequence 1: NP_732393.1
• Gene: gukh / 53563
• FlyBaseID: FBgn0026239
• Length: 1788
• Species: Drosophila melanogaster
• Sequence 2: NP_008921.1
• Gene: WASF2 / 10163
• HGNCID: 12733
• Length: 498
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 58/250 - (23%)
• Similarity: 93/250 - (37%)
• Gaps: 58/250 - (23%)

  Fly   138 EFDSISNITLSNALRQLASLVLIASDIFDDLQRDLQAVGERAGRVQRKIAAVERRVCAYDPKTVT 202
            |.:.::||||:|.:|||.||...|.|||.:|.........|...:..::..::.:|...|||...
Human    24 ELECVTNITLANVIRQLGSLSKYAEDIFGELFTQANTFASRVSSLAERVDRLQVKVTQLDPKEEE 88

  Fly   203 VPESDLLTFAQRKHHFETDKSFQQELFTGETRPLSVRQLYTEAGKELPVATGATATALASLAHSQ 267
            |....:.|    :..|.:.....|:||...:.|:.|.:.|.......|:               .
Human    89 VSLQGINT----RKAFRSSTIQDQKLFDRNSLPVPVLETYNTCDTPPPL---------------N 134

  Fly   268 SLIPSRSISFNGEVLSSD---------HEVLQLNGSTDTED-------HLLCVSD---FGNAN-R 312
            :|.|.|..........:|         .::||     ||:|       |.....|   .||.| |
Human   135 NLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQ-----DTKDIMKEKRKHRKEKKDNPNRGNVNPR 194

  Fly   313 KLRTRIDAEIEIRLPAAIEDLRKWTSSEALGDVTVTP---------DCMHHVDTS 358
            |::||.:...::::.....:     |.|.||.....|         .|:.:||.|
Human   195 KIKTRKEEWEKMKMGQEFVE-----SKEKLGTSGYPPTLVYQNGSIGCVENVDAS 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gukh	NP_732393.1	None
WASF2	NP_008921.1	Scar homology domain	1..170		39/169 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..203		9/29 (31%)
		Proline-rich region	333..400
		WH2	428..>479	CDD:425359
		WH2 domain	437..452
		Acidic region	483..498