DRSC/TRiP Functional Genomics Resources

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Protein Alignment gukh and WASF2

DIOPT Version :9

Sequence 1:NP_732393.1 Gene:gukh / 53563 FlyBaseID:FBgn0026239 Length:1788 Species:Drosophila melanogaster
Sequence 2:NP_008921.1 Gene:WASF2 / 10163 HGNCID:12733 Length:498 Species:Homo sapiens


Alignment Length:250 Identity:58/250 - (23%)
Similarity:93/250 - (37%) Gaps:58/250 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   138 EFDSISNITLSNALRQLASLVLIASDIFDDLQRDLQAVGERAGRVQRKIAAVERRVCAYDPKTVT 202
            |.:.::||||:|.:|||.||...|.|||.:|.........|...:..::..::.:|...|||...
Human    24 ELECVTNITLANVIRQLGSLSKYAEDIFGELFTQANTFASRVSSLAERVDRLQVKVTQLDPKEEE 88

  Fly   203 VPESDLLTFAQRKHHFETDKSFQQELFTGETRPLSVRQLYTEAGKELPVATGATATALASLAHSQ 267
            |....:.|    :..|.:.....|:||...:.|:.|.:.|.......|:               .
Human    89 VSLQGINT----RKAFRSSTIQDQKLFDRNSLPVPVLETYNTCDTPPPL---------------N 134

  Fly   268 SLIPSRSISFNGEVLSSD---------HEVLQLNGSTDTED-------HLLCVSD---FGNAN-R 312
            :|.|.|..........:|         .::||     ||:|       |.....|   .||.| |
Human   135 NLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQ-----DTKDIMKEKRKHRKEKKDNPNRGNVNPR 194

  Fly   313 KLRTRIDAEIEIRLPAAIEDLRKWTSSEALGDVTVTP---------DCMHHVDTS 358
            |::||.:...::::.....:     |.|.||.....|         .|:.:||.|
Human   195 KIKTRKEEWEKMKMGQEFVE-----SKEKLGTSGYPPTLVYQNGSIGCVENVDAS 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
gukhNP_732393.1 NHS <818..>846 CDD:291922
WASF2NP_008921.1 Scar homology domain 1..170 39/169 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 173..203 9/29 (31%)
Proline-rich region 333..400
WH2 428..>479 CDD:425359
WH2 domain 437..452
actin-binding sequence 450..453 CDD:409196
Acidic region 483..498
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12902
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

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