Protein Alignment cmet and KIP3

DIOPT Version :9

• Sequence 1: NP_524993.3
• Gene: cmet / 53561
• FlyBaseID: FBgn0040232
• Length: 2189
• Species: Drosophila melanogaster
• Sequence 2: NP_011299.1
• Gene: KIP3 / 852655
• SGDID: S000003184
• Length: 805
• Species: Saccharomyces cerevisiae
• Alignment Length: 634
• Identity: 180/634 - (28%)
• Similarity: 281/634 - (44%)
• Gaps: 122/634 - (19%)

  Fly    44 YVFDYVFDEGASNQEVFDRMAKHIVHACMQGFNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAK 108
            :|||.:|||.:|...|:......::.:.:.|||.|:||||.|..|||||:.|....||::.||.:
Yeast   153 FVFDKLFDETSSQARVYKETTSPLLDSVLDGFNSTVFAYGATGCGKTYTVSGTPSQPGIIFLAME 217

  Fly   109 EIFQQISS-ETERDFLLRVGYIEIYNEKIYDLLNKKNQDLKI---HESGNGIVNVNCEECIITSE 169
            |:|.:|:. :.|:||.:.:.|:|||||:|.|||..:....::   .::.|.|...|.......:.
Yeast   218 ELFNKITDLKDEKDFEISLSYLEIYNERIRDLLKPETPSKRLVIREDTQNHIKVANLSYHHPNTV 282

  Fly   170 VDLLRLLCLGNKERTVGETNMNERSSRSHAIFKI-IIESRK-----SDHSDDDAVIQSVLNLVDL 228
            .|::.|:..||..||...|..||.||||||:.:| |:::.|     |.|:      .:.|:::||
Yeast   283 EDVMDLVVQGNINRTTSPTEANEVSSRSHAVLQIHIMQTNKLVDLTSQHT------FATLSIIDL 341

  Fly   229 AGSERADQTGARGARLKEGGHINKSLLFLSNVIKSLSENADNRFTN--YRDSKLTRILQASLGGN 291
            ||||||..|..||.||.||.:||:|||.|.|.|.:|..|..:|..:  ||||||||:|:.|||||
Yeast   342 AGSERAAATRNRGIRLHEGANINRSLLALGNCINALCLNDGSRSCHIPYRDSKLTRLLKFSLGGN 406

  Fly   292 AFTSIICTIKPSI--MEESQSTLSFATRAKKIRIK---------PQVNEMVSDATMMKR-----L 340
            ..|.:|..|.||.  .:|:.:||.:|.|||:|:.|         ..|...:...|..||     .
Yeast   407 CKTVMIVCISPSSSHYDETLNTLKYANRAKEIKTKIIRNQQSLSRHVGSYLKMITEQKRQIEELR 471

  Fly   341 EREIKVL------------KDKLAEEERKNENQQKVEHLE-------------------RQIKHD 374
            |||.|::            |.:||..|..|..||....:|                   :.:|.:
Yeast   472 EREEKMISLKLTKYKLNKEKIQLAINECVNRVQQTYAGVETYQVAKTLKSLILCKRRFLQMVKLE 536

  Fly   375 MHKIIC--GHSLSDKGQQKRRRTWCPTASGS-HLELAETGTTEDRIDQFPKVSHLPKPVFFHTSN 436
            :..:|.  ....|...:.:...:.|...||. :.::.|.....|..|....|.|....:..:...
Yeast   537 VDNLILLFEREESTAAEMQPVISNCRMISGQLYNKIHELEMKFDETDTLSSVIHQVHSIDLNKLR 601

  Fly   437 AGKRWDNIPKTINILGSLDIGTESNSISEEFLPAECIDFGSPRPDVL--KPMLTIRQLPDLPLTP 499
            ..:.||.....:.:...|      |.|||           ..|.::|  ..::|.:.:.|..|..
Yeast   602 EMEDWDETYDLVYLESCL------NQISE-----------LQRNEILVNSSIMTEKLMSDPGLNS 649

  Fly   500 KGPL-------TTDKIKKEIQDL----QMFTSLEKHFEVECE------EVQGLKEKLAEVTAQRD 547
            :...       .|..|:..||||    :.|.|..:.|....:      .:..:....|::....:
Yeast   650 RFKFLSKWLMNRTPNIESIIQDLVHIDEEFESFARTFIANPDSNFTNTNINIINTTAADLAVPAE 714

  Fly   548 NLEQESLAEK---------------ERYDALEKEVTSLRADNEAANSKI 581
            .|::::.::|               |....||.|   |..|.:|..|::
Yeast   715 TLQRQNFSQKKVKWTSPDLSPSPMIEPQPELEPE---LHQDQDAIASEV 760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cmet	NP_524993.3	KISc	8..328	CDD:214526	121/306 (40%)
		Motor_domain	8..321	CDD:277568	119/290 (41%)
		Smc	<680..1449	CDD:224117
		TMPIT	779..>867	CDD:285135
		Smc	1042..1910	CDD:224117
KIP3	NP_011299.1	KISc_KIP3_like	82..438	CDD:276821	119/290 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0242
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810