Protein Alignment cmet and HIK

DIOPT Version :10

• Sequence 1: NP_524993.3
• Gene: cmet / 53561
• FlyBaseID: FBgn0040232
• Length: 2189
• Species: Drosophila melanogaster
• Sequence 2: NP_173273.2
• Gene: HIK / 838418
• AraportID: AT1G18370
• Length: 974
• Species: Arabidopsis thaliana
• Alignment Length: 1119
• Identity: 279/1119 - (24%)
• Similarity: 447/1119 - (39%)
• Gaps: 299/1119 - (26%)

  Fly     2 SAKNASSIQVCIKVRP---------------C--EPGLTSLWQVKERRSIHLADSHAEPYVFDYV 49
            |......|.|.:::||               |  :..:.|..||:||  :|    |...:.||.|
plant    25 SRSREEKIVVTVRLRPMNKRELLAKDQVAWECVNDHTIVSKPQVQER--LH----HQSSFTFDKV 83

  Fly    50 FDEGASNQEVFDRMAKHIVHACMQGFNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQI 114
            |...:..:.|::...|::..:.:.|.|.||||||||||||||||.      ||...|..:|:..|
plant    84 FGPESLTENVYEDGVKNVALSALMGINATIFAYGQTSSGKTYTMR------GVTEKAVNDIYNHI 142

  Fly   115 SSETERDFLLRVGYIEIYNEKIYDLLNK-KNQDLK-IHESGNGIVNVNCEECIITSEVDLLRLLC 177
            ....||||.:::..:|||||.:.||||. ..:.|| :.:...|.|.....|....::..|..|:.
plant   143 IKTPERDFTIKISGLEIYNENVRDLLNSDSGRALKLLDDPEKGTVVEKLVEETANNDNHLRHLIS 207

  Fly   178 LGNKERTVGETNMNERSSRSHAIFKIIIESRKSDHSDDDAVIQSVLNLVDLAGSERADQTGARGA 242
            :...:|.||||.:|:.|||||.|.::.|:|...::||......:.||.|||||||||.|:.|.|.
plant   208 ICEAQRQVGETALNDTSSRSHQIIRLTIQSTHRENSDCVRSYMASLNFVDLAGSERASQSQADGT 272

  Fly   243 RLKEGGHINKSLLFLSNVIKSLSENADNRFTNYRDSKLTRILQASLGGNAFTSIICTIKPSI--M 305
            ||:||.|||.||:.|:.||:.||....:....|||||||||||.||||||.|:||||:.|::  :
plant   273 RLREGCHINLSLMTLTTVIRKLSVGKRSGHIPYRDSKLTRILQHSLGGNARTAIICTLSPALAHV 337

  Fly   306 EESQSTLSFATRAKKIRIKPQVNEMVSDATMMKRLEREIKVLKDKLAEEERK-----NENQQKVE 365
            |:|::||.||.|||::.....||.:|||..::|.|::|:..|     |.||:     .|...|::
plant   338 EQSRNTLYFANRAKEVTNNAHVNMVVSDKQLVKHLQKEVARL-----EAERRTPGPSTEKDFKIQ 397

  Fly   366 HLERQIKHDMHKIICGHSLSDKGQQKRRRTWCPTASGSHLELAETGTTEDRIDQFPKVSHLPKPV 430
            .:|.:|                |:.:|:|      ..:.::|.|
plant   398 QMEMEI----------------GELRRQR------DDAQIQLEE--------------------- 419

  Fly   431 FFHTSNAGKRWDNIPKTINILGSLDIGTESNSISEEFLPAECIDFGSPRPDVLKPMLTIRQLPDL 495
             ......|.:..|  |.:|                        .|.||.|.|.|.:..     .:
plant   420 -LRQKLQGDQQQN--KGLN------------------------PFESPDPPVRKCLSY-----SV 452

  Fly   496 PLTPKGPLTT----DKIKKEIQDLQM--------FTSLEKHFEVECEEVQGLKEKLAEVTAQRDN 548
            .:||.....|    ::.:|......|        ||.:.     |..:::.|:|:|.|...
plant   453 AVTPSSENKTLNRNERARKTTMRQSMIRQSSTAPFTLMH-----EIRKLEHLQEQLGEEAT---- 508

  Fly   549 LEQESLAEKERYDALEKEVTSLRADNEAANSKISELE---EKLSTLKQTMRIMEVENQVAVGLEF 610
                     :..:.|:|||...|..|:.|...|::|:   .::.|:|.:..:.||.:.:|...
plant   509 ---------KALEVLQKEVACHRLGNQDAAQTIAKLQAEIREMRTVKPSAMLKEVGDVIAPNK-- 562

  Fly   611 EFEAHKKSSKLRVDDLLSALLEKESTIESLQKSLDNL----------------TRDVLRNSKEGH 659
            ...|:.|....|:....|.:...|..:||:|||:|.|                |::....||:..
plant   563 SVSANLKEEITRLHSQGSTIANLEEQLESVQKSIDKLVMSLPSNISAGDETPKTKNHHHQSKKKK 627

  Fly   660 MLSIAPEQEDIAGDSICNKCEELEKLIADLESKKNSCECDQLRLEIVSVRDKLESVESAFNLASS 724
            :|.:.|       .|..|:...|:...:.|.:.:...:||                  |.|.|..
plant   628 LLPLTP-------SSASNRQNFLKSPCSPLSASRQVLDCD------------------AENKAPQ 667

  Fly   725 EIIQKATDCERLSKELSTSQNAFGQLQERYDALDQQWQAQQAGITTLHEKHEHVQEKYQKLQEEY 789
            |....|.                                  .|.||.....:...:|    .||.
plant   668 ENNSSAA----------------------------------RGATTPQGSEKETPQK----GEES 694

  Fly   790 EQLESRA-----RSASSAEFQRLQNDNTKFQADIASLNERLEEAQNMLTEVQNSESTVEKLRIQN 849
            ..:.||.     |.:||...:::|.   .||      |...|..:::...|...:..|.||:.|.
plant   695 GDVSSREGTPGYRRSSSVNMKKMQQ---MFQ------NAAEENVRSIRAYVTELKERVAKLQYQK 750

  Fly   850 HELTAKIKELETNFEEMQREYDCLSNQLMESVQENDALREEIKQRPTSHVEESMRSSGISSDFDE 914
            ..|..::.|||.|..         :...:|: :||..:.:|.:.:...|:          :..:|
plant   751 QLLVCQVLELEANDG---------AGYSVEN-EENTIMEDEEQNQVAWHI----------TFIEE 795

  Fly   915 QKQDINLLHQFVQLSESVQQIELQHHSGISRLFRANQMKLDQSEPGLKLCLESAEYIEEDNRQSD 979
            ::|.|.|.|        |..:.:.|.:....||:.:|......|..|:......:::.|....:.
plant   796 RQQIIELWH--------VCHVSIIHRTQFYLLFKGDQADQIYMEVELRRLTWLEQHLAEVGNATP 852

  Fly   980 ATEPIC----------LKGFLKRHRFQIKRLSQE-------------HVDMGEEKRLLDIISQLE 1021
            |..  |          :|...:...|..||::..             .|.:..::|.|..:::|.
plant   853 ARN--CDESVVSLSSSIKALRREREFLAKRVNSRLTPEEREELYMKWDVPLEGKQRKLQFVNKLW 915

  Fly  1022 QEIEEKSALMEATE 1035
            .:..:...:.|:.|
plant   916 TDPYDSRHVQESAE 929

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cmet	NP_524993.3	Motor_domain	8..321	CDD:473979	137/333 (41%)
		SMC_prok_B	539..1431	CDD:274008	100/544 (18%)
		SMC_prok_B	1137..1926	CDD:274008
		YhaN	1717..2182	CDD:443752
HIK	NP_173273.2	KISc_CENP_E	31..353	CDD:276825	137/333 (41%)
		COG4913	<467..>599	CDD:443941	34/151 (23%)
		DUF3490	791..955	CDD:463424	25/149 (17%)