Protein Alignment cmet and AT3G12020

DIOPT Version :10

• Sequence 1: NP_524993.3
• Gene: cmet / 53561
• FlyBaseID: FBgn0040232
• Length: 2189
• Species: Drosophila melanogaster
• Sequence 2: NP_001189866.1
• Gene: AT3G12020 / 820376
• AraportID: AT3G12020
• Length: 1044
• Species: Arabidopsis thaliana
• Alignment Length: 1221
• Identity: 316/1221 - (25%)
• Similarity: 505/1221 - (41%)
• Gaps: 308/1221 - (25%)

  Fly     4 KNASSIQVCIKVRPCEP-----GLTSLWQVKERRSIHLADSHAEPYVFDYVFDEGASNQEVFDRM 63
            ::..::.|.::.||..|     |....|.......:....:....|.:|.||....:.:.|:|..
plant    65 RSKENVTVTVRFRPLSPREIRQGEEVAWYADGETIVRNEHNPTIAYAYDRVFGPTTTTRNVYDIA 129

  Fly    64 AKHIVHACMQGFNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQISSETERDFLLRVGY 128
            |.|:|:..|:|.||||||||.||||||:||.||:::||::.||.|:.|..|.....|:||||:.|
plant   130 AHHVVNGAMEGINGTIFAYGVTSSGKTHTMHGDQRSPGIIPLAVKDAFSIIQETPNREFLLRISY 194

  Fly   129 IEIYNEKIYDLLNKKNQDLKIHESGNGIVNVNCEECIITSEVDLLRLLCLGNKERTVGETNMNER 193
            :|||||.:.||||....:|:|.|...|......:|.::.|....|.|:..|.::|.||.||.|..
plant   195 MEIYNEVVNDLLNPAGHNLRIREDKQGTFVEGIKEEVVLSPAHALSLIAAGEEQRHVGSTNFNLL 259

  Fly   194 SSRSHAIFKIIIESRK-SDHSDDDAVIQSVLNLVDLAGSERADQTGARGARLKEGGHINKSLLFL 257
            |||||.||.:.|||.. .|.|..:||..|.|||||||||| :.:....|.|.|||.:||||||.|
plant   260 SSRSHTIFTLTIESSPLGDKSKGEAVHLSQLNLVDLAGSE-SSKVETSGVRRKEGSYINKSLLTL 323

  Fly   258 SNVIKSLSENADNRFTN--YRDSKLTRILQASLGGNAFTSIICTIKP--SIMEESQSTLSFATRA 318
            ..||..|:   |.|.::  |||||||||||:||.|:...|:|||:.|  |..||:.:||.||.||
plant   324 GTVISKLT---DVRASHVPYRDSKLTRILQSSLSGHDRVSLICTVTPASSSSEETHNTLKFAHRA 385

  Fly   319 KKIRIKPQVNEMVSDATMMKRLEREIKVLKDKLAEEERKNENQQKVEHLERQIKHDMHKIICGHS 383
            |.|.|:.:.|:::.:.:::|:.:|||:.||::|   |:..:....|..|:.....|:  ::....
plant   386 KHIEIQAEQNKIIDEKSLIKKYQREIRQLKEEL---EQLKQEIVPVPQLKDIGADDI--VLLKQK 445

  Fly   384 LSDKGQQKRRRTWCPTASGSHLELAETGTTEDRIDQFPKVSHLPKPVFFHTSNAGKRWDNIPKTI 448
            |.| ||.|.:         |.||..|    |.:.....::..|.|.:...|.|
plant   446 LED-GQVKLQ---------SRLEEEE----EAKAALLSRIQRLTKLILVSTKN------------ 484

  Fly   449 NILGSLDIGTESNSISEEFLPAECIDFGSPRPDVLKPMLTIRQLPDLPLTPKGPLTTDKIKKEIQ 513
                     .:::.:...|.|.....||.            .:|..||..          ::::.
plant   485 ---------PQASRLPHRFNPRRRHSFGE------------EELAYLPYK----------RRDMM 518

  Fly   514 D---LQMFTSLEKHFEVECEEVQGLKEKLAEVTAQRDNLEQESLAEKERYDALEKEVTSLRADNE 575
            |   |.::.|:|.:.|:                  |||..:|.  :|.|...|...:...:.|:.
plant   519 DDEQLDLYVSVEGNHEI------------------RDNAYREE--KKTRKHGLLNWLKPKKRDHS 563

  Fly   576 AANSKISELEEKLSTLKQTMRIMEVENQVAVGLEFEFEAHKKSSKLRVDDLLSALLEKESTIESL 640
            ::.|..|.:.:..||                    ........|.|..:..||   |....:|.|
plant   564 SSASDQSSVVKSNST--------------------PSTPQGGGSHLHTESRLS---EGSPLMEQL 605

  Fly   641 QKSLDNLTRDVLRNSKEGHMLSIAPEQEDIAGDSICNKCEELEKLIADLESKKNSCECDQLRLEI 705
            .:..::  |:.|.:|  .|.:.| ||                       .|.|.|.|.|.||
plant   606 SEPRED--REALEDS--SHEMEI-PE-----------------------TSNKMSDELDLLR--- 639

  Fly   706 VSVRDKLESVESAFNLASSEIIQKATDCERLSKELSTS-QNAFGQLQERYDALDQQWQAQQAGIT 769
              .:.|:.|.|:|..|:|         .:|:|.|.:.| ||.  ::.|....|:...:|:...|.
plant   640 --EQKKILSEEAALQLSS---------LKRMSDEAAKSPQNE--EINEEIKVLNDDIKAKNDQIA 691

  Fly   770 TLHEKHEHVQEKYQKLQEEYEQLESRARSASSAEFQRLQNDNTKFQADIASLNERLE-------- 826
            ||.      ::....:...:|.|:......:.||.:...|:.: |:.::..|...::
plant   692 TLE------RQIMDFVMTSHEALDKSDIMQAVAELRDQLNEKS-FELEVIELFLFMQFFFIYAEV 749

  Fly   827 -------------EAQNMLTEVQNSESTVEKLRIQNHE----LTAKIKELETNFEEMQREYDCL- 873
                         .||..|:...|..|:|..::.|..:    ||.|:....|.|....   .||
plant   750 RDGFAIAWIRLFILAQYYLSSYLNKVSSVYIIKYQYSKRQTILTMKLMVCSTLFSHSS---SCLQ 811

  Fly   874 ---------SNQLMESVQENDALREEI---KQRPTSHVEESMRSSGISSDFDEQKQDINLLHQFV 926
                     ...|.|...|.:.|:||:   ||:.:..:|.:.     .:...|.|||..
plant   812 VKAADNRIIQQTLNEKTCECEVLQEEVANLKQQLSEALELAQ-----GTKIKELKQDAK------ 865

  Fly   927 QLSESVQQIELQHHSGISRLFRANQMKLDQSEPGLKLCLESAEYIEEDNRQSDATEPICLKGFLK 991
            :||||.:|:||::.                     ||..||:                ..||...
plant   866 ELSESKEQLELRNR---------------------KLAEESS----------------YAKGLAS 893

  Fly   992 RHRFQIKRLSQEHVD-MGEEKRLLDIISQLEQEIEEKSALMEATEATINEMREQMTNLE-----S 1050
            ....::|.||:|... |.:.:||...::..:..|.:::.....|....|..||.:...:     |
plant   894 AAAVELKALSEEVAKLMNQNERLAAELATQKSPIAQRNKTGTTTNVRNNGRRESLAKRQEHDSPS 958

  Fly  1051 ALLEKSVIINKVED--YQRQIESLEKQNAEMTMVYEELQDRVTRESSMSESLLRVPPDEDTLPGC 1113
            ..|::.:.::|..:  |:..:...|::.||:..:.||.:.|        |:.|
plant   959 MELKRELRMSKERELSYEAALGEKEQREAELERILEETKQR--------EAYL------------ 1003

  Fly  1114 PTSPSRREQEVATLKTSITELQ------SQVSDLKAELENHLRQIQLKDGN 1158
                   |.|:|.:...:::|:      |::||..:|    .||.:..:|:
plant  1004 -------ENELANMWVLVSKLRRSQGADSEISDSISE----TRQTEQTEGS 1043

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cmet	NP_524993.3	Motor_domain	8..321	CDD:473979	143/322 (44%)
		SMC_prok_B	539..1431	CDD:274008	133/673 (20%)
		SMC_prok_B	1137..1926	CDD:274008	6/22 (27%)
		YhaN	1717..2182	CDD:443752
AT3G12020	NP_001189866.1	KISc_CENP_E	69..388	CDD:276825	143/322 (44%)
		SMC_prok_B	<372..>1041	CDD:274008	181/906 (20%)