Protein Alignment cmet and AT3G10180

DIOPT Version :10

• Sequence 1: NP_524993.3
• Gene: cmet / 53561
• FlyBaseID: FBgn0040232
• Length: 2189
• Species: Drosophila melanogaster
• Sequence 2: NP_187629.3
• Gene: AT3G10180 / 820180
• AraportID: AT3G10180
• Length: 1273
• Species: Arabidopsis thaliana
• Alignment Length: 1473
• Identity: 399/1473 - (27%)
• Similarity: 646/1473 - (43%)
• Gaps: 362/1473 - (24%)

  Fly     9 IQVCIKVRP--CEPGLTSLWQVKERRSIHLADSHAEPYVFDYVFDEGASNQEVFDRMAKHIVHAC 71
            |.|.::.||  .|...||.|::.. .||.:.:..:..:.||.:|.|.....:|::...|.||.|.
plant     4 IHVSVRARPLSSEDAKTSPWKISS-DSIFMPNHSSLAFEFDRIFREDCKTVQVYEARTKEIVSAA 67

  Fly    72 MQGFNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQISSETERDFLLRVGYIEIYNEKI 136
            ::|||||:||||||:||||:||.|....|||:.||..::|..|..:..|:||||:.|:|||||.|
plant    68 VRGFNGTVFAYGQTNSGKTHTMRGSPIEPGVIPLAVHDLFDTIYQDASREFLLRMSYLEIYNEDI 132

  Fly   137 YDLLNKKNQDLKIHES-GNGIVNVNCEECIITSEVDLLRLLCLGNKERTVGETNMNERSSRSHAI 200
            .|||..:::.|:|||: ..||......|.|:.|...:|.::..|...|.:||||||..|||||.|
plant   133 NDLLAPEHRKLQIHENLEKGIFVAGLREEIVASPQQVLEMMEFGESHRHIGETNMNLYSSRSHTI 197

  Fly   201 FKIIIESRKSDHSDD-----DAVIQSVLNLVDLAGSERADQTGARGARLKEGGHINKSLLFLSNV 260
            |::|||||:....:.     |||..||||||||||||||.:|||.|.|||||.||||||:.|..|
plant   198 FRMIIESRQKMQDEGVGNSCDAVRVSVLNLVDLAGSERAAKTGAEGVRLKEGSHINKSLMTLGTV 262

  Fly   261 IKSLSENADNR--FTNYRDSKLTRILQASLGGNAFTSIIC--TIKPSIMEESQSTLSFATRAKKI 321
            ||.|||..:.:  ...|||||||||||.:|||||.|:|||  |:.|...:|::|:|.||:||.::
plant   263 IKKLSEGVETQGGHVPYRDSKLTRILQPALGGNANTAIICNITLAPIHADETKSSLQFASRALRV 327

  Fly   322 RIKPQVNEMVSDATMMKRLEREIKVLKDKL--------------------------------AEE 354
            .....|||:::||.::||.::||:.|:.||                                .||
plant   328 TNCAHVNEILTDAALLKRQKKEIEELRSKLKTSHSDHSEEEILNLRNTLLKSELERERIALELEE 392

  Fly   355 ERKNENQQK--VEHLERQIKHDMHKIICGHSLSDKGQQ------KRRRTWCPTASGSHLELAETG 411
            |:|.:.|::  ::...::|| ::..::...:..:|.:|      |||.|||..      :|:...
plant   393 EKKAQAQRERVLQEQAKKIK-NLSSMVLLSNRDEKREQDHFKKGKRRDTWCIG------KLSRDS 450

  Fly   412 TTEDRIDQFPKVSHLPKPVFFHTSNAGKRWDNIPKTINILGSLDIGTES----NSISEEFLPAEC 472
            |:||:.:...:.|.|       .|...:|     :|..:|...::..|.    |...|:.:....
plant   451 TSEDQSNVLSRGSSL-------ESARSER-----ETGPLLPFSELVNEPLYNINEEDEDSIEGTL 503

  Fly   473 IDFGSPRPDVLKPMLTIRQLPDLPLTPKGPLTT----DKIKKEIQDLQMFTSLEK---HFEVECE 530
            .|...|.|..| ..:|.|:.|.  :..|.|:..    |:|::|.:.|.:....|:   ..::||
plant   504 EDSVLPDPCAL-VNVTSRKKPS--IKQKNPVVVENELDRIQREYEALLLQYETERIISEIQIEC- 564

  Fly   531 EVQGLKEKLAEVTAQRDNLEQESLAEKERYDA---LEKEVTSLRADNEAANSKISELEEKLSTLK 592
                ||.||.|     |.|..::..::.....   .|:.|.:|| |.||. ..|.:|:||::.|
plant   565 ----LKVKLGE-----DGLSGDAKCKQSEVVGNVHCEEHVVNLR-DPEAI-LLIKQLQEKINML- 617

  Fly   593 QTMRIMEVENQVAVGLEFEFEAHKKSSKLRVDDLLSALLEK---------------ESTIESLQK 642
                                |..|.||...:|||:....|:               .:..|..|.
plant   618 --------------------ELEKSSSNRNLDDLVMVATEQNICAREKFAEIQEEIHAAREEAQV 662

  Fly   643 SLDNLTRDVLRNSKEGHMLSIAPEQEDIAGDSICNKCEELEKLIADLESKKNSCE---------- 697
            :.:.|.      |||..::.:..|.    .:|:.|...|:|.|.::.:..|.|.|
plant   663 AREQLV------SKESEVIDVINEN----FNSLVNVATEIEVLESEFQKYKASVETISSVMNEGL 717

  Fly   698 ---------CDQLRLEIVSVRDKLESVESAFNLASSEIIQKATDCERLSKELSTSQNAFGQLQER 753
                     .....|.:....::.:|:.:::....|.:.:|..|.|  :::|...:...| ||.:
plant   718 QDFAFFSPLIHDFTLFVRQSSEQHDSLINSYQTVQSSLKKKVLDVE--NEKLLLQEQCAG-LQSQ 779

  Fly   754 YDALDQQWQAQQAGITTLHEKHE--------HVQ---------------EKYQKLQEEYEQLESR 795
            .:.|:|:.|..:..:..|.|.||        |::               ::.:.|::::|:.:::
plant   780 IEELNQEAQKHETSLKMLSEHHESERSDLLSHIECLEKDIGSLSSSSLAKEKENLRKDFEKTKTK 844

  Fly   796 ARSASSAEFQRLQN---DNTKFQADIASLNERLE--EAQNMLTE--VQNSESTVEKL-------R 846
            .:...|    :|:|   |.||.:|:.||....|:  .:|..|.|  :...||...|.       |
plant   845 LKDTES----KLKNSMQDKTKLEAEKASAERELKRLHSQKALLERDISKQESFAGKRRDSLLVER 905

  Fly   847 IQNHELTAKIKELETNFEEMQREYDCLSNQLM-------ESVQENDALREEIKQRPTSHVEESMR 904
            ..|..|..:.|:||....||:.....|..:|.       |::..||.|..||... |..:|.|
plant   906 SANQSLQEEFKQLEVLAFEMETTIASLEEELAAERGEKEEALCRNDGLGSEITDL-TEKLEHS-- 967

  Fly   905 SSGISSDFDEQKQDINLLHQFVQLSESVQQIELQHHSGISRLFRANQMKLDQSEPGLKLCLESAE 969
                ::..:..:.|:..|...:::|.|.||                     |.|..:|..||..|
plant   968 ----NTKLEHLQNDVTELKTRLEVSSSDQQ---------------------QLETNVKQLLEEKE 1007

  Fly   970 YIEEDNRQSDATEPICLKGFLKRHRFQIKRLSQEHVDMGEEKRLLDIISQ-LEQEIEEKSALME- 1032
            .                   |..|      |:...::|.|||.:.....: |.:.:|||..|.:
plant  1008 E-------------------LAMH------LANSLLEMEEEKAIWSSKEKALTEAVEEKIRLYKN 1047

  Fly  1033 -ATEATINEMREQMTNLESALLEKSVIINKVEDYQRQIESLEKQNAEMTMVYEELQDRVTRESSM 1096
             ..|:...||.|:...|||..||...:.:::.        ..::||:        ||   :|||:
plant  1048 IQIESLSKEMSEEKKELESCRLECVTLADRLR--------CSEENAK--------QD---KESSL 1093

  Fly  1097 SESLLRVPPDEDTLPGCPTSPSRREQEVATLKTSITELQSQVSDLKAELENHLRQIQLKDGNIAR 1161
            .:| |.:....|.|... .:.|::.|||         |:|.:..||:|:::
plant  1094 EKS-LEIDRLGDELRSA-DAVSKQSQEV---------LKSDIDILKSEVQH-------------- 1133

  Fly  1162 LQTDFEEMSERCLSMEVRLAELDEDTKQKQELLDRQAQKLSDDLCLIDQLQKKNAQLVEQYHKAT 1226
                      .|...:....|:|..|.::|.||.| .::||.:|...::.|.:||:      ...
plant  1134 ----------ACKMSDTFQREMDYVTSERQGLLAR-IEELSKELASSNRWQIENAK------NPI 1181

  Fly  1227 ESLSLADAKPDQILLSSQYDSQIEKLNQLLNAAKDELHDVRRIKDDEISALRMEFLLQIETNEKE 1291
            :.|:|.        :||| ::.:.|.....|..|.:|....|.....:.|:.:.:...::.:|..
plant  1182 QDLTLK--------ISSQ-ETNLHKDAAAENKEKAKLKMRLRGMQARLDAISLRYKQSVQESELM 1237

  Fly  1292 NQAKFYAELQETKDRYESNVAELKEKL-------LQVEETLSS 1327
            |:            :::...|:|||||       |.:::.||:
plant  1238 NR------------KFKEASAKLKEKLASKALEVLDLKKQLSA 1268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cmet	NP_524993.3	Motor_domain	8..321	CDD:473979	157/323 (49%)
		SMC_prok_B	539..1431	CDD:274008	183/880 (21%)
		SMC_prok_B	1137..1926	CDD:274008	39/198 (20%)
		YhaN	1717..2182	CDD:443752
AT3G10180	NP_187629.3	KISc_CENP_E	4..327	CDD:276825	157/323 (49%)
		sbcc	<335..904	CDD:129705	132/640 (21%)
		SMC_prok_B	644..>1268	CDD:274008	158/775 (20%)