Protein Alignment cmet and CG5004

DIOPT Version :10

• Sequence 1: NP_524993.3
• Gene: cmet / 53561
• FlyBaseID: FBgn0040232
• Length: 2189
• Species: Drosophila melanogaster
• Sequence 2: NP_573195.1
• Gene: CG5004 / 32698
• FlyBaseID: FBgn0260748
• Length: 1247
• Species: Drosophila melanogaster
• Alignment Length: 899
• Identity: 173/899 - (19%)
• Similarity: 312/899 - (34%)
• Gaps: 278/899 - (30%)

  Fly    80 FAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQISSETERDFLLRV-----------GYIEIYN 133
            :|.|..|:|..:.:   ..|..:.    ||..||...:..:|.|.:|           |.::||:
  Fly   219 YAKGVGSNGGYWNV---PSNAAIY----KEQHQQQHQQAPQDLLTKVNNDRYDRYPKAGGLQIYS 276

  Fly   134 EKIYDLLNKKNQDLKIHESGNGIVNVNCEECIITSEVDLLRLLCLGNKERTVGETNMNERSSRSH 198
                  :|..|.|:     .||....|.......:|::.:..:|....:|.....:.:..||.|.
  Fly   277 ------MNGVNSDI-----NNGPATGNNSGTGGGAELEDMLKICTEYADRNNSMPSTHNVSSTSS 330

  Fly   199 AIFKIIIESR-KSDHS----------DDDAVIQSVLNL-----------VDLAGSERADQTGA-- 239
            .....|:::| |::.|          ...|.:.|..|:           |.|.|..|.:..|.
  Fly   331 ITSSPIVQNRIKTNGSLPRDKNKSPFPQQAGVASSANISLLSSSSGYENVRLLGPNRVEINGQIH 395

  Fly   240 RGARLKEGGH---INKSLLFLSNVIKSLSENADNRFTNYRDSKL------TRILQASLG------ 289
            ..|...:||.   ::.:.|..:..:::..||.:...:.....|.      |:|....:.
  Fly   396 VPASAGDGGSSSGVSSNALAPTAAVRASHENLNQNHSATTGGKYVPQSPRTKIRTNCMSPKKDVS 460

  Fly   290 -GNAFTSIICTIKPSIMEESQSTLSFATRAKKIRI-----------KPQVNEMVSDATMMKRLER 342
             ||||.   ..|.|..:..|    :..:.:|.|.|           .|..|:......:.|..||
  Fly   461 FGNAFA---LAISPPPLASS----AVVSTSKPIPIPSMVKPPLAPKPPAPNQQRDYEQLFKSFER 518

  Fly   343 EIKVLKDKLAEEERKNENQQKVEHLERQIKHDMHKIICGHSLSDKGQQKRRRTWCPTASGSHLEL 407
            :.:.| |::...:|.|:|   :.:|.                                  .:|:.
  Fly   519 KQQQL-DRMVPAKRSNKN---INNLT----------------------------------LNLQS 545

  Fly   408 AETGTTEDRIDQFPKVSHLPKPVFFHTSNAGKRWDNIPKTINILGSLDIGTESNSISEEFLPAEC 472
            .|:.|      |.||.|..|.|.              |::|::              |:....|.
  Fly   546 VESQT------QSPKPSRKPAPA--------------PRSIHL--------------EQRQRREL 576

  Fly   473 IDFGSPRPDVLKPMLTIRQLPDLPLTPKGPLTTDKIKKEIQDLQMFTSLEKHFEVECEEVQGLKE 537
            |.    |...||     |:|.:||  |...:...::|...|.|....|...       ::|.|:.
  Fly   577 IQ----RRKQLK-----RELAELP--PSAGIEGLELKLGEQPLAPSASPRL-------QLQALQN 623

  Fly   538 KLAEVTAQRDN---LEQESLAE-KERYDALEKEVTSLRA-----DNEAANSKISELEEKLSTLKQ 593
            ::..:.|||:.   :|:...|: |:..:..:.::..|||     .|.|.      |:|:|..:.:
  Fly   624 RVCRLEAQRNATRVMEENQQAKLKQSIEIKQDQLKKLRAMLKQKPNNAC------LKEELQLVCE 682

  Fly   594 TMRIMEVENQVAVGLEFEF------------EAHKKSSKLRVDDLLSALL-------EKESTIES 639
            :   :|.:.:....|||::            |..::..:|.::..|:||.       |:..:..|
  Fly   683 S---LESDRKTFEDLEFQYFEEESEHHASHEEFKRQEQRLMLEAELAALRIQIGPDEEEPGSPTS 744

  Fly   640 LQKSLDNLTRDVLRNSKEGHMLSIAPE---QEDIAGDSICNKCEELEKLIADLESKK-------- 693
            ...:..||...|:..|..|....:.|:   |||:...|:........|:.|:..:.|
  Fly   745 PGSTGSNLVNGVMSQSLFGSAELLCPKRRNQEDLMSKSVNENMFYNHKIEANTSTPKRLPLQLFE 809

  Fly   694 ----NSCECDQLRLEIVSVRDKLESVESAFNLASSEIIQKATDCERLSK-----ELSTSQNAFGQ 749
                .|||.....|.:...|.::..:|..        :....|.:|..|     .:|.||.|..:
  Fly   810 DLAGGSCEQISFNLSLQGDRFEVNPLERR--------VPSQDDIDRSCKVANDAPISASQGASTK 866

  Fly   750 LQERYDALDQQWQ---AQQAGITTLHEK----------HEHVQEKY----QKLQEEYEQLESRAR 797
            :.:....:::..:   |||......||:          |:..:.:|    |:..|:..||||.|.
  Fly   867 IFDSIMEIERNRKLLLAQQGHQVIEHERQKMYDLKKKSHDEARTQYLLSTQQSMEQQRQLESDAN 931

  Fly   798 SASSAE-FQRLQNDNTKFQADIASLNERLEE---------AQNMLTEVQNSEST 841
            ....|: |::         .::..||::..|         |.:....|||.:||
  Fly   932 GGKDAKLFEK---------TELQKLNQKPGEPVDDQVQKIAGDKENNVQNRKST 976

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cmet	NP_524993.3	Motor_domain	8..321	CDD:473979	56/291 (19%)
		SMC_prok_B	539..1431	CDD:274008	76/378 (20%)
		SMC_prok_B	1137..1926	CDD:274008
		YhaN	1717..2182	CDD:443752
CG5004	NP_573195.1	FHA_PHLB1	1..122	CDD:438765
		SMC_N	<570..730	CDD:481474	39/186 (21%)
		Caldesmon	<664..801	CDD:460421	28/145 (19%)
		PH-like	1142..1242	CDD:473070