Protein Alignment cmet and klp3

DIOPT Version :9

• Sequence 1: NP_524993.3
• Gene: cmet / 53561
• FlyBaseID: FBgn0040232
• Length: 2189
• Species: Drosophila melanogaster
• Sequence 2: NP_594686.1
• Gene: klp3 / 2542195
• PomBaseID: SPAC1834.07
• Length: 554
• Species: Schizosaccharomyces pombe
• Alignment Length: 680
• Identity: 187/680 - (27%)
• Similarity: 300/680 - (44%)
• Gaps: 171/680 - (25%)

  Fly     7 SSIQVCIKVRPCEP------GLTSLWQVKERRSIHLADS-HAEPYVFDYVFDEGASNQEVFDRMA 64
            :||:|..::||...      |...::.:.: .::|:..| ::..:|||.||...::..::|....
pombe     2 TSIKVVCRIRPTNQLEQDLGGNNVIYPLND-STVHIETSDYSGNFVFDRVFHPSSTQNDIFSYSI 65

  Fly    65 KHIVHACMQGFNGTIFAYGQTSSGKTYTMMGDEQN---PGVMVLAAKEIFQQI-SSETERDFLLR 125
            :..|.....|:|||:.|||||.|||||||||.|.|   .|:.....:.||.:| .|.:..::.::
pombe    66 ESTVDDLFLGYNGTVLAYGQTGSGKTYTMMGIENNFEKEGMTPRMLRRIFDKIRDSPSTTEYEVK 130

  Fly   126 VGYIEIYNEKIYDLLNKKNQDLKIHESG-NGIVNVNCEECIITSEVDLLRLLCLGNKERTVGETN 189
            |.|:|||.|||:|||::||..|.:||.. .|:.....:...::||.:.|.:|..|...|.|..|:
pombe   131 VSYMEIYMEKIHDLLSEKNDRLTVHEDKLQGVYVQGLKTIYVSSETEALDILNKGMGSRAVASTS 195

  Fly   190 MNERSSRSHAIFKIIIESRKSDHSDDDAVIQSVLNLVDLAGSERADQTGARGARLKEGGHINKSL 254
            ||.:|||||:||  ::|..::| ::.....:..|.||||||||...::||.|..|:|...||:||
pombe   196 MNAQSSRSHSIF--VLEVVQTD-TESGETRRGRLFLVDLAGSESVGKSGAVGQTLEEAKKINRSL 257

  Fly   255 LFLSNVIKSLSENADNRFTN--YRDSKLTRILQASLGGNAFTSIICTIKPSIME--ESQSTLSFA 315
            ..|..||.||:   |::.::  ||||||||||:.|||||:.|::|....|....  |:.|||.|.
pombe   258 STLGMVINSLT---DSKLSHVPYRDSKLTRILKESLGGNSRTTLIINCSPDSYNATETLSTLRFG 319

  Fly   316 TRAKKIRIKPQVNEMVSDATMMKRLEREIKVLKDKLAEEERKNENQQKVEHLERQIKHDMHKIIC 380
            .|||.|:.|..||..:|    :..::|::.:.||.|:                        :.:|
pombe   320 HRAKSIKNKAVVNSELS----VDEMKRQLYIYKDALS------------------------RCVC 356

  Fly   381 GHSLSDKGQQK--RRRTWCPTASGSH-LELAETGTTEDRIDQFPKVSHLPKPVFFHTSNAGKRWD 442
            |..:::.....  ....|    ||.| |.|                           ||..:: .
pombe   357 GARINNNLDYNNCHSNVW----SGEHSLTL---------------------------SNLAEK-S 389

  Fly   443 NIPKTINILGSLDIGTESNSISEEFLPAECIDFGSPRPDVLKPMLTIRQLPDLPLTPKGPLTTDK 507
            |:.:...|.|:..| .|||:..:|                                    .|...
pombe   390 NLKEAEIIQGNRTI-QESNNDRDE------------------------------------STVAS 417

  Fly   508 IKKEIQDLQMFTSLEKHFEVECEEVQGL----KEKLAE-VTAQRDNLEQESLAEKERYDALEKEV 567
            |.:...|......|....::|.::..|:    |::|:: :||..|        .:|||..|.|
pombe   418 IHRHNFDSDSINRLYAEAQLELKQRDGVLSSTKQQLSDLMTALGD--------AQERYVELVK-- 472

  Fly   568 TSLRADNEAANSKI---SELEEKLSTLKQTMRIMEVENQVAVGLEFEFEAHKKSSKLRVDDLLSA 629
                  |...||.:   :.|.:|..                      |...:|.....:::..:.
pombe   473 ------NHRVNSNLTANNSLNDKPG----------------------FTIEQKDKNFSINNERNN 509

  Fly   630 LLEKESTIESLQKSLDNLTRDVLRN--SKE 657
            .|:|.||::|...:|.|:.|.:::.  |||
pombe   510 FLQKLSTLDSSLAALVNVQRKLIKALISKE 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cmet	NP_524993.3	KISc	8..328	CDD:214526	128/335 (38%)
		Motor_domain	8..321	CDD:277568	126/328 (38%)
		Smc	<680..1449	CDD:224117
		TMPIT	779..>867	CDD:285135
		Smc	1042..1910	CDD:224117
klp3	NP_594686.1	KIP1	1..546	CDD:227392	187/680 (28%)
		KISc_KHC_KIF5	1..325	CDD:276820	126/329 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000669
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000