Protein Alignment cmet and klp-11

DIOPT Version :9

• Sequence 1: NP_524993.3
• Gene: cmet / 53561
• FlyBaseID: FBgn0040232
• Length: 2189
• Species: Drosophila melanogaster
• Sequence 2: NP_001369897.1
• Gene: klp-11 / 177685
• WormBaseID: WBGene00002222
• Length: 782
• Species: Caenorhabditis elegans
• Alignment Length: 765
• Identity: 203/765 - (26%)
• Similarity: 334/765 - (43%)
• Gaps: 237/765 - (30%)

  Fly     3 AKNASSIQVCIKVRPCEPGLTSLWQVKERRSIHLADSHAEPYVFDYVFDEGASNQEVFDRMAKHI 67
            |.|.|.|   :.:|| :.|...|...||:      |..::.:.||.::||.::..::::...:.:
 Worm    29 ANNYSKI---VHMRP-QRGQIELKNPKEQ------DEPSKDFTFDAIYDENSTQSDLYEETFRDL 83

  Fly    68 VHACMQGFNGTIFAYGQTSSGKTYTMMGDEQNP---GVMVLAAKEIFQQISSETERDFLLRVGYI 129
            |.:.:.|:|.||||||||.:|||:||.|...:|   ||:......||:.:::...:::|:|..|:
 Worm    84 VDSVLNGYNATIFAYGQTGTGKTHTMEGKSSDPEQRGVIYKCIDHIFEHMAASHNQEYLVRASYL 148

  Fly   130 EIYNEKIYDLLN-KKNQDLKIHESGNGIVNVNCEECIITSEV-DLLRLLCLGNKERTVGETNMNE 192
            |||.|::.|||. :.|:.|:|.|..:|.|.|......:|..| ::..::..||..|:||.|||||
 Worm   149 EIYQEELRDLLEAESNKKLEIKERPDGGVYVKDLTSKLTRTVGEIHEVMIRGNGHRSVGRTNMNE 213

  Fly   193 RSSRSHAIFKIIIESRKSDHSDDDAVIQSVLNLVDLAGSERADQTGARGARLKEGGHINKSLLFL 257
            .||||||||.|.:|..:.....:..:....|||||||||||..:|||.|.|.||...||.||..|
 Worm   214 HSSRSHAIFIITVECSRIGEDGESHITVGRLNLVDLAGSERQSKTGATGERFKEATKINLSLSAL 278

  Fly   258 SNVIKSLSENADNRFTNYRDSKLTRILQASLGGNAFTSIICTIKPSI--MEESQSTLSFATRAKK 320
            .|||.:|.: |.:....||||||||:||.|||||:.|.::..|.|:.  .||:..||.:|.|||.
 Worm   279 GNVISALVD-AKSAHIPYRDSKLTRLLQDSLGGNSKTVMVACIGPASYNFEETLGTLRYANRAKN 342

  Fly   321 IRIKPQVNEMVSDATMMKRLEREIKVLKDKLAEEERKNEN--------------QQKVEHLERQ- 370
            |:.:|::||...|| :::..:.||::|:::|.:.:.::.:              :..:|.:::.
 Worm   343 IKNQPKINEDPKDA-LLREFQEEIEMLREQLKQRKTRSRDGATQSFYDAERAKLEDDIEAIQKDD 406

  Fly   371 --IKHDMHKIICGHSLSDKGQQKRRRTWCPTASGSHLELAETGTTEDRIDQFPKVSHLPKPVFFH 433
              |||:..::|  ..:.:|                | :|.|    ::||:| .:|:.
 Worm   407 SLIKHEKDRLI--REIQEK----------------H-DLLE----KERIEQ-ARVAE-------- 439

  Fly   434 TSNAGKRWDNIPKTINILGSLDIGTESNSISEEFLPAECIDFGSPRPDVLKPMLTIRQLPDLPLT 498
                        :..||...|.:|:|.:.
 Worm   440 ------------RIANIQSRLIVGSEEDG------------------------------------ 456

  Fly   499 PKGPLTTDKIKKEIQDLQMFTSLEKHFEVECEEVQGLKEKLAEVTAQRDNLEQESLAEKERYDAL 563
                                 .||..          .||:.|::..:|..|.::...|:|..:||
 Worm   457 ---------------------RLESR----------TKEQHAQLEKKRRELAEQKRREREMVEAL 490

  Fly   564 EKEVTSLRADNEAANSKISELEEKLSTLKQTMRIMEVENQVAVGLEFEFEAHKKSSKLRVDDLLS 628
            |::                  ||....||||.                       |.||.
 Worm   491 ERQ------------------EEDTVDLKQTF-----------------------SDLRT----- 509

  Fly   629 ALLEKESTIESLQKSLDNLTRDVLRNSKEGHMLSIAPEQEDIAGDSICNKCEELEKLIADLESKK 693
               |.|:..:.|:|.|..|.:  .||           |..|::| :..::.::|::.||::..
 Worm   510 ---EVEAKTKKLKKMLIKLRQ--ARN-----------EIRDVSG-AYSDERQDLDQTIAEVSK-- 555

  Fly   694 NSCECDQLRLEIVSV-----RDKLESVE--------------SAFNLASS 724
                  :|:|:::.|     ||..|.::              :||...||
 Worm   556 ------ELKLKLLIVENFIPRDVSERIKERAEWNEDSFEWNVNAFQSTSS 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cmet	NP_524993.3	KISc	8..328	CDD:214526	129/326 (40%)
		Motor_domain	8..321	CDD:277568	127/319 (40%)
		Smc	<680..1449	CDD:224117	13/64 (20%)
		TMPIT	779..>867	CDD:285135
		Smc	1042..1910	CDD:224117
klp-11	NP_001369897.1	Motor_domain	12..343	CDD:419868	130/324 (40%)
		SMC_prok_B	337..>584	CDD:274008	73/429 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910