Protein Alignment cmet and kif18b

DIOPT Version :9

• Sequence 1: NP_524993.3
• Gene: cmet / 53561
• FlyBaseID: FBgn0040232
• Length: 2189
• Species: Drosophila melanogaster
• Sequence 2: XP_002939283.3
• Gene: kif18b / 100490953
• XenbaseID: XB-GENE-5960389
• Length: 872
• Species: Xenopus tropicalis
• Alignment Length: 1065
• Identity: 252/1065 - (23%)
• Similarity: 416/1065 - (39%)
• Gaps: 318/1065 - (29%)

  Fly     2 SAKNASSIQVCIKVRPCEPGLTSLWQVKERRSIHLADSHA---------------EP-------- 43
            |:....::.|.::|||...        :|:...|    ||               ||
 Frog     6 SSTEEGNVSVVVRVRPPNQ--------REQEGNH----HAVVQVVDHNMLVFDPDEPETTGVFSS 58

  Fly    44 ---------------YVFDYVFDEGASNQEVFDRMAKHIVHACMQGFNGTIFAYGQTSSGKTYTM 93
                           ::||.:|.|.:..|:||:...|.|:...:.|:|.::||||.|.:|||:||
 Frog    59 LRGNDGPKRKGKDMKFIFDRIFGENSRQQDVFEHTTKEILDGVLNGYNCSVFAYGATGAGKTHTM 123

  Fly    94 MGDEQNPGVMVLAAKEIFQQISS-ETERDFLLRVGYIEIYNEKIYDLLNKKNQDLKIHES-GNGI 156
            :|.|.:||||.|...|::::|.: :.|:...:.:.|:|:|||:|.|||..:. .|.|.|. ..|:
 Frog   124 LGSEADPGVMYLTMVELYRRIEAIKEEKSCEVLISYLEVYNEQIQDLLEPRG-SLAIREDPQKGV 187

  Fly   157 VNVNCEECIITSEVDLLRLLCLGNKERTVGETNMNERSSRSHAIFKIIIESRKSDHSDDDAVIQS 221
            |..........|...||::|..||..||...|:.|..||.|||:|:|.::.:....|....|..:
 Frog   188 VVQGLSFHQPKSADQLLQMLASGNLNRTQHPTDANASSSHSHAVFQIYVKQQDRTVSISQDVRVA 252

  Fly   222 VLNLVDLAGSERADQTGARGARLKEGGHINKSLLFLSNVIKSLSE-NADNRFTNYRDSKLTRILQ 285
            .::|:||||||||..|.|:|.||:||.:||:|||.|.|||.:|:: .:......||||||||:|:
 Frog   253 KMSLIDLAGSERASTTNAKGERLREGANINRSLLALINVINALADAKSKKAHIPYRDSKLTRLLK 317

  Fly   286 ASLGGNAFTSIICTIKPSIM--EESQSTLSFATRAKKIRIKPQVNEMVSD------ATMMKRLER 342
            .|:|||..|.:|..|.||.:  :::.:||.:|.|||:|::..:.|.:..|      |.:.:.|:.
 Frog   318 DSIGGNCRTVMIAAISPSALSYDDTYNTLKYANRAKEIKLSMKSNVINLDCHISKYAAVCEELKA 382

  Fly   343 EIKVLKDKLAEEERKNENQQKVEHLERQIKHDMHKIICGHSLSDKGQQKRRRTWCPTASGSHLEL 407
            |:..|::||...|.|.:......               .:||.||...:|.            |.
 Frog   383 EVAELREKLRFYEMKEQPDDDTS---------------DNSLQDKTSPRRE------------EH 420

  Fly   408 AETGTTEDRIDQFPKVSHLPKPVFFHTSNAGKRWDNIPKTINILGSLDIGTESNSISEEFLPAEC 472
            ::.|:.|.                      |.            |:|.:.| |:..|::..|||
 Frog   421 SDLGSPEQ----------------------GS------------GALLLST-SSCQSQDHKPAE- 449

  Fly   473 IDFGSPRPDVLKPMLTIRQLPDLPLT--------PKGPLTTDKIKKEIQDLQMFTSLEKHFEVEC 529
                      :.|    |:...:||.        .|.|...:.:|.:..: ::.|||......:|
 Frog   450 ----------MNP----RKWDQVPLNCSLGREELEKNPCLHEALKDDAAE-RLVTSLLNFVRKQC 499

  Fly   530 E--EVQGLKEKLAEVTAQRDNLEQ-ESLAEKERYDALEKEVTSLRADNEAANSKISELEEKLSTL 591
            |  ::.||.....|     |.|.| |.||              ||. .:|...|::|.|:
 Frog   500 EILKLAGLYTPELE-----DELRQLEGLA--------------LRG-QKATAEKVTEKEQ----- 539

  Fly   592 KQTMRIMEVENQVAVGLEFEFEAHKKSSKL----RVDDLLSALLEKESTIESLQKSLDNLTRDVL 652
                          |..|.|.|.||:..::    .|:|::..:  ||..||      |.:.....
 Frog   540 --------------VTEEHEMETHKEQEEVPQTPLVEDVVFDI--KEEVIE------DPVPPARK 582

  Fly   653 RNSKEGHMLSIAPEQEDIAGDSICNKCEELEKLIADLESKKNSCECDQLRLEIVSVRDKLESVES 717
            |...:.:...|.|:                           ||   ..||..||.|:
 Frog   583 RKPGKRYRADILPD---------------------------NS---PSLRSPIVPVK-------- 609

  Fly   718 AFNLASSEIIQKATDCERLSKELSTSQNAFGQLQERYDALDQQWQAQQAGITTLHEKHEHVQEKY 782
                                              .|.:|.:...:|:.||:.:..|    ||.|
 Frog   610 ----------------------------------RRREATNTPTKARLAGVPSTPE----VQVK- 635

  Fly   783 QKLQEEYEQLESRARSASSAEFQRLQNDNTKFQADIASLNERLEEAQNMLTEVQNSE---STVEK 844
               :.....:.||.|.:..:....|.: |.|   ||||      :..::.|..|.::   .||.|
 Frog   636 ---RPRKSSIPSRCRVSLRSSLNLLPS-NAK---DIAS------QPPSLCTPKQTAKIQSQTVTK 687

  Fly   845 LR-------IQNHELTAKI-------KELETNFEEMQREYDCLSNQLMESVQENDALREEIKQRP 895
            .|       |||   .|.:       :::.|.|:  ..|..|..:::.::|....:.....:..|
 Frog   688 SRMPLGTSAIQN---CASVPAAALAPRDMNTTFD--LSEEGCFVSEMDKTVTFGTSDFPGWENVP 747

  Fly   896 TSHVEESMRSSGISSDFDEQKQDINLLHQFVQLSESVQQIELQHHSGISRLFRANQMKLDQSEPG 960
            ..:::.:...|...:.|..:...:|.::.....|.:......:..|..|.:.||.:..|.||
 Frog   748 IHNIDTTFGKSSDVAVFSVKGLSVNHMNANQMTSAAKSYSHKRRRSSSSSMSRAGKGTLAQS--- 809

  Fly   961 LKLCLESAEYIEEDNRQSDATEPIC 985
             ::.......:::..:....:|.||
 Frog   810 -RIARLQMSTVKKSQQPPTISESIC 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cmet	NP_524993.3	KISc	8..328	CDD:214526	125/362 (35%)
		Motor_domain	8..321	CDD:277568	124/355 (35%)
		Smc	<680..1449	CDD:224117	56/323 (17%)
		TMPIT	779..>867	CDD:285135	24/104 (23%)
		Smc	1042..1910	CDD:224117
kif18b	XP_002939283.3	KISc_KIP3_like	23..355	CDD:276821	120/344 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910