Protein Alignment cic and hbp1

DIOPT Version :9

• Sequence 1: NP_001262755.1
• Gene: cic / 53560
• FlyBaseID: FBgn0262582
• Length: 2150
• Species: Drosophila melanogaster
• Sequence 2: NP_001019602.2
• Gene: hbp1 / 554137
• ZFINID: ZDB-GENE-050522-414
• Length: 494
• Species: Danio rerio
• Alignment Length: 500
• Identity: 104/500 - (20%)
• Similarity: 168/500 - (33%)
• Gaps: 159/500 - (31%)

  Fly   862 GSNSNTHVAATAAATSTVGAQPLPPQTTPVSLVMHAPPPQQQPL-----QQQHHHHQPPPPPPAS 921
            ||:|:|:.....|..:|....|         |:.:||..:..|:     ....|.:..||...:|
Zfish    98 GSDSHTNWLTELANIATSPQSP---------LLQNAPHTRSSPVHIFSSSSSLHSYARPPLSSSS 153

  Fly   922 LPAPSAP------PTSGSSSSHNSVGHATSVIRISSSQQQHQQQQQHQQQAHP-HVVVSGGQTFH 979
            .|:|:..      .|..||.|.      :.|..:||..........|...:.. |..:.|
Zfish   154 APSPARSHMRERRRTRASSESE------SGVFCMSSLSDDDDLGWSHSWPSTAWHCFLKG----- 207

  Fly   980 PVIVDATQLSVPLPPTTVSFHQ-PNTPTSTAASVASMSQD-------KMLAKNGYNAPWFKLLPH 1036
                           |.:.||: ||.....|..|....:|       :......|.:...||:..
Zfish   208 ---------------TRLRFHKGPNVEWQEADDVLESDEDSDDERGAQSNPMKSYGSDGLKLVIF 257

  Fly  1037 MTPMS------KASPAPVTP---TLTTSAS-----------------SYNVVMMQQQQQHQQLQQ 1075
            ...:|      |.:..|.:|   .||...|                 |..||      :|.....
Zfish   258 EESVSFGQSVLKLTFDPGSPEAGLLTAECSLDHPFFVKNKGWSSFYPSLTVV------RHGIPCY 316

  Fly  1076 QQQLQQQQQSPPQMPLNHNNNHLIVSAPLSSPGKPLNCSMNDAKVAAAAAAAAVANQRQKQQQE- 1139
            ..|:......|......:.::.::.....|....||:.|       |....:::..||:..|..
Zfish   317 DMQVGDLCLPPGHRDAINCDDSVVFDTFKSYDFTPLDSS-------AVYVLSSMGRQRRASQSSG 374

  Fly  1140 ---EPD-DQLDDDVFETTTPGISANSKKQTAAMRLPTHNSNIRKLEECHDDGAAGAPATSAAKRR 1200
               .|| |:|:...|                     ||:|:..|.:..|..|::||..|
Zfish   375 GAVSPDCDKLEALGF---------------------THHSSSSKSQRSHASGSSGATPT------ 412

  Fly  1201 SQSLSALQQQQQQQQQAGAAGTAAGQPANKKIRRPMNAFMIFSKKHRKMVHKKHPNQDNRTVSKI 1265
                                          |.:|||||||:|:||:|....:.:|.:|||.:|.|
Zfish   413 ------------------------------KCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVI 447

  Fly  1266 LGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCSKDRRKSS 1310
            ||:.|..:|.|::..|...|.::.:...:|:|:   |.|.:|.:|
Zfish   448 LGDKWKKMKNEERRMYTMEAKALAEEQKRLNPD---CWKRKRTNS 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cic	NP_001262755.1	DUF4819	349..431	CDD:292708
		SOX-TCF_HMG-box	1231..1302	CDD:238684	27/70 (39%)
hbp1	NP_001019602.2	AXH	210..328	CDD:285689	22/123 (18%)
		SOX-TCF_HMG-box	413..484	CDD:238684	28/73 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2746
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900