Protein Alignment cic and SoxN

DIOPT Version :9

• Sequence 1: NP_001262755.1
• Gene: cic / 53560
• FlyBaseID: FBgn0262582
• Length: 2150
• Species: Drosophila melanogaster
• Sequence 2: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Alignment Length: 863
• Identity: 191/863 - (22%)
• Similarity: 297/863 - (34%)
• Gaps: 266/863 - (30%)

  Fly   988 LSVPLPP--TTVSFH-QPNTPTSTAASVASMSQDKMLAK--NGYNAPWFKLLPHMTPMSKASPAP 1047
            |...:||  |:.:.| ...:|.|..|.:.::.|..:...  :.:|.....:..|:.  :..||.|
  Fly    13 LHATMPPHHTSAALHGHAASPYSALAPLMNLGQSHLTHSQLSHHNHHHHHMSAHIA--ASQSPNP 75

  Fly  1048 VTPTLTTSASSYNVVMMQQQQQHQQLQQQQQLQQQQQSPPQMPLNHNNNHLIVSAPLSSPGKPLN 1112
            ::...::.|::.|         ..|:.||||.||||||.|.    |:::.|
  Fly    76 LSSLQSSMANTLN---------GSQVGQQQQQQQQQQSSPL----HSSSEL-------------- 113

  Fly  1113 CSMNDAKVAAAAAAAAVANQRQKQQQEEPDDQ-LDDDVFETTTPGISANSKKQTAAMRLPTHNSN 1176
             |...:.:.:....:.|::|:..|||:....| |......::..|.|:|:...:|     |.|.|
  Fly   114 -SPTQSSIGSHHMTSPVSHQQHTQQQQHGQQQHLGAGSALSSLTGGSSNNNNNSA-----TANKN 172

  Fly  1177 IRKLEECHDDGAAGAPATSAAKRRSQSLSALQQQQQQQQQAGAAGTAAGQPANKKIRRPMNAFMI 1241
                                                 ||.|            .:::|||||||:
  Fly   173 -------------------------------------QQHA------------DRVKRPMNAFMV 188

  Fly  1242 FSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCSKDR 1306
            :|:..|:.:...:|...|..:||.||..|..|...:|..:.:.|..::..|.|.||::|:  :.|
  Fly   189 WSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKY--RPR 251

  Fly  1307 RKSSTSTATP-----GGKASGAAGTGDAKQRLVS---VDGSDSLEHDMCPSTPGGSGSCGGQGIS 1363
            ||:.|.|.|.     ||...|....|.|....|:   |.|.......:..|  |||.:......:
  Fly   252 RKTKTLTKTKEKYPMGGLMPGQTVGGGAPGEPVTPTRVQGQPGQNQSLNGS--GGSAAAAAAAAA 314

  Fly  1364 SDLQGDIIPLTIDNYNSTCDEAPTTISMKGNG---NGKLMKNELPSDEDEQMLVVEEEQQQQTVK 1425
            :..|    ....|.|..   .||       ||   ||.:|..: |:.          ....||
  Fly   315 AAAQ----QARQDMYQM---NAP-------NGYMPNGYMMHAD-PAG----------AAAYQT-- 352

  Fly  1426 KIDLHCRERVNDSDMDDTPFDYRKQQPEANQRSAEEHSTSGANGQAINAPPLSGGEREITLKPKA 1490
                                .|..|. .|.||....|..:  ||.|: ...:|||:..
  Fly   353 --------------------SYMGQH-YAAQRYDMGHMYN--NGYAM-YQTVSGGQTS------- 386

  Fly  1491 IKAHPVLESNMLPYTQMSIYTQYTSPKNPIGVTPFQPTGGAFKSMPISPK--GSGGKPEDAGSLQ 1553
                        ||.  |...|..|| :|.|       |.:.:..|.||.  |.||......|.|
  Fly   387 ------------PYG--SSLQQPGSP-SPYG-------GSSLQQQPGSPTPYGGGGGGGGQVSCQ 429

  Fly  1554 AHIKQE-DIKQEP----PSPYKLNN--------------GSGSASGGGVVSAPPPNSGSVGAIFN 1599
            :|...: .||.||    ||...|||              .|.:|:.....:|.....|.:..:.|
  Fly   430 SHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAAAAAAAAAGGGELNHLMN 494

  Fly  1600 -FNVPTATALSQKQFHYPMHHPHRSPTDLRAAHQACVPSSPAGMGLGHAANIATPPASAPAQIMG 1663
             :::|      .:|.|. :|:...|| ||:..||                ::.......|.|.:
  Fly   495 MYHLP------DEQRHL-LHYQTDSP-DLQQQHQ----------------SMQQQQQHLPQQHL- 534

  Fly  1664 GGPASQKMFFAMTHPYTLLQRSHQPGTPSLEHLQ-LDAFAPGGYTLRNHNGLSSLPPPVSAQPTM 1727
               :.|.......| :|:.|:..|   ..|:|.| |.|.||..:. ...:...:....||..|.:
  Fly   535 ---SQQHQQIPQQH-HTMQQQQQQ---HHLQHQQSLRAMAPLAHMXEMASAYGAAGSSVSVSPPL 592

  Fly  1728 LLHGYPPSHGVEPPARSPSYKSMPSTP-------KSATYLMSAPPERGMDGGMSGCASAAASGGD 1785
                             |.|  ||:.|       :....|::..|.....|...|.:||.:||..
  Fly   593 -----------------PPY--MPTAPQQQQQQQQQQQQLLNGRPSPTASGSSGGRSSAHSSGHT 638

  Fly  1786 ESDIDADGQQFILAPTPA 1803
            .:...|....:.|.|:.|
  Fly   639 AAHSPALAAAYQLTPSAA 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cic	NP_001262755.1	DUF4819	349..431	CDD:292708
		SOX-TCF_HMG-box	1231..1302	CDD:238684	24/70 (34%)
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	24/72 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I3058
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910