Protein Alignment cic and D

DIOPT Version :10

• Sequence 1: NP_001262755.1
• Gene: cic / 53560
• FlyBaseID: FBgn0262582
• Length: 2150
• Species: Drosophila melanogaster
• Sequence 2: NP_524066.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Alignment Length: 354
• Identity: 80/354 - (22%)
• Similarity: 133/354 - (37%)
• Gaps: 87/354 - (24%)

  Fly  1073 LQQQQQL-----QQQQQSPPQMPLN-----HNNNHLIVSAPLSSPGKPLNCSMNDAKVAAAAAAA 1127
            |.|.|.|     |.|.|..|.|.::     |.:..|  :|...||..|....:|.:.......::
  Fly    14 LGQAQGLEDYAPQSQLQLSPGMDMDIKRVLHYSQSL--AAMGGSPNGPAGQGVNGSSGMGHHMSS 76

  Fly  1128 AVANQRQKQQQEEPDDQLDDDVFETTTPGISANSKKQTAAMRLPTHNSNIRKLEECHDDGAAGA- 1191
            .:......|                      |.|.:||.     :.||:|         |:||:
  Fly    77 HMTPHHMHQ----------------------AVSAQQTL-----SPNSSI---------GSAGSL 105

  Fly  1192 PATSAAKRRSQSLSALQQQQQQQQQAG--AAGTAAGQPANKKIRRPMNAFMIFSKKHRKMVHKKH 1254
            .:.|:.......|::    ....|.||  :..|:.||..:  |:|||||||::|:..|:.:.|.:
  Fly   106 GSQSSLGSNGSGLNS----SSGHQSAGMHSLATSPGQEGH--IKRPMNAFMVWSRLQRRQIAKDN 164

  Fly  1255 PNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCSKDRRKSSTSTATPGGK 1319
            |...|..:||.||..|..|...:|..:.:.|..::..|.|.||::|:..:.:.|:..:....||.
  Fly   165 PKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKNPLTAGPQGGL 229

  Fly  1320 ASGAAGTGDAKQRLVSVDGSDSLEHDMCPSTPGGSGSCG---------------GQGISSDLQGD 1369
            ...|.|.|  :|:|.:..|:             |:|...               .||......|.
  Fly   230 QMQAGGMG--QQKLGAGPGA-------------GAGGYNPFHQLPPYFAPSHHLDQGYPVPYFGG 279

  Fly  1370 IIPLTIDNYNSTCDEAPTTISMKGNGNGK 1398
            ..||.:...:.:...|...::.:|...|:
  Fly   280 FDPLALSKLHQSQAAAAAAVNNQGQQQGQ 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cic	NP_001262755.1	DUF4819	349..432	CDD:465014
		HMG-box_CIC-like	1231..1308	CDD:438806	26/76 (34%)
D	NP_524066.1	HMG-box_SoxB	140..219	CDD:438790	26/80 (33%)