DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cic and sox3

DIOPT Version :9

Sequence 1:	NP_001262755.1	Gene:	cic / 53560	FlyBaseID:	FBgn0262582	Length:	2150	Species:	Drosophila melanogaster
Sequence 2:	NP_001001811.2	Gene:	sox3 / 30529	ZFINID:	ZDB-GENE-980526-333	Length:	300	Species:	Danio rerio

Alignment Length:	131	Identity:	42/131 - (32%)
Similarity:	67/131 - (51%)	Gaps:	14/131 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly  1214 QQQAGAAGTAAGQPAN--KKIRRPMNAFMIFSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPE 1276
            |...|:........||  .:::|||||||::|:..|:.:.:::|...|..:||.||..|..|...
Zfish    15 QSNTGSVTGGKNNSANDQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGADWKLLTDA 79

  Fly  1277 QKAQYHELASSVKDAHFKLHPEWKWCSKDRRKSST-----STATPGG-KASGAAGTGDAKQRLVS 1335
            :|..:.:.|..::..|.|.||::|:  :.|||:.|     ..:.||| .|.||....:|    ||
Zfish    80 EKRPFIDEAKRLRAMHMKEHPDYKY--RPRRKTKTLLKKDKYSLPGGLLAPGANAVNNA----VS 138

  Fly  1336 V 1336
            |
Zfish   139 V 139

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cic	NP_001262755.1	DUF4819	349..431	CDD:292708
cic	NP_001262755.1	SOX-TCF_HMG-box	1231..1302	CDD:238684	24/70 (34%)
sox3	NP_001001811.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35		4/19 (21%)
		SOX-TCF_HMG-box	34..105	CDD:238684	24/72 (33%)
		SOXp	104..182	CDD:289133	14/42 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910