Protein Alignment cic and sox19a

DIOPT Version :10

• Sequence 1: NP_001262755.1
• Gene: cic / 53560
• FlyBaseID: FBgn0262582
• Length: 2150
• Species: Drosophila melanogaster
• Sequence 2: NP_570983.2
• Gene: sox19a / 30038
• ZFINID: ZDB-GENE-980526-102
• Length: 297
• Species: Danio rerio
• Alignment Length: 266
• Identity: 62/266 - (23%)
• Similarity: 106/266 - (39%)
• Gaps: 59/266 - (22%)

  Fly  1171 PTHNSNIRKLEECHDDGAAGAPATSAAKRRSQSLSALQQQQQQQQQAGAAGTAAGQPANKKIRRP 1235
            |||.|            |.|....:.......:..|:..||||          :..|.: |::||
Zfish    15 PTHQS------------AQGMTQLNGGVTHGSAKPAVNSQQQQ----------SSDPMD-KVKRP 56

  Fly  1236 MNAFMIFSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWK 1300
            |||||::|:..|:.:.:::|...|..:||.||..|..|...:|..:.:.|..::..|.|.:|::|
Zfish    57 MNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLTDAEKRPFIDEAKRLRALHMKEYPDYK 121

  Fly  1301 WCSKDRRKSSTSTATPGGK----------ASGAAGTGDAKQRLVSVDGSDSLEHDMCPSTPGGSG 1355
            :..:.:.|.......|..|          |:.|.|:|          ||..::       ..|.|
Zfish   122 YKPRRKTKPVLKKDNPAAKYPLSAGNLLAAAAAQGSG----------GSPRMD-------SYGWG 169

  Fly  1356 SCGG-QGISSDLQGDIIPLTIDNYNSTCDEAPTTIS-----MKG-NGNGKLMKNELPSDEDEQML 1413
            ..|| .|:.:|..|  ....:..|:.:..:.|:.::     |.| |....:..:..|......|.
Zfish   170 HTGGYPGMQTDALG--YSQQLHRYDLSALQYPSAMATAQTYMNGANSYNPMSYSSTPQQPSPVMS 232

  Fly  1414 VVEEEQ 1419
            :|:.||
Zfish   233 MVKPEQ 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cic	NP_001262755.1	DUF4819	349..432	CDD:465014
		HMG-box_CIC-like	1231..1308	CDD:438806	24/76 (32%)
sox19a	NP_570983.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		12/59 (20%)
		HMG-box_SoxB	51..129	CDD:438790	24/78 (31%)
		SOXp	122..>187	CDD:463537	16/83 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..255		5/20 (25%)