back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wun2 and PLPP3

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_003704.3	Gene:	PLPP3 / 8613	HGNCID:	9229	Length:	311	Species:	Homo sapiens

Alignment Length:	300	Identity:	107/300 - (35%)
Similarity:	158/300 - (52%)	Gaps:	36/300 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 NVKLDLQLPTFVDSTRSQGSLYAVASNKKPPLRGPRQIFGRILTDLCLLSCVGLPMLGFSLWGEA 114
            |.|.|   ...|..:::.||   .|.|..|...|.:::. .|..||..|...|||.|  .:....
Human     3 NYKYD---KAIVPESKNGGS---PALNNNPRRSGSKRVL-LICLDLFCLFMAGLPFL--IIETST 58

  Fly   115 VK---RGFFCDDSSLRHPYR-DSTMPSWILYLMCGALPLTVMLVVEFFRGQDKRLHSPFPKSTMC 175
            :|   |||:|:|.|:::|.: ..|:...:|..:...:.:..::..||:|    ..:....:||:.
Human    59 IKPYHRGFYCNDESIKYPLKTGETINDAVLCAVGIVIAILAIITGEFYR----IYYLKKSRSTIQ 119

  Fly   176 SGYHLCHLELPTWLVECYHRMGIFIFGLGVEQLSTNIAKYSIGRLRPHFYTLCQPVMKDGTTCSD 240
            :.|          :...|.::|.|:||..:.|..|:|||.|||||||||.::|.|.... ..||:
Human   120 NPY----------VAALYKQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCNPDFSQ-INCSE 173

  Fly   241 PINAARYIEEFTCAAVDITSKQLKDMRLSFPSGHASFACYSMLYLVIYLHRRMQWKQLRMLCHLL 305
                 .||:.:.|...|   .::::.|.||.||||||:.|:|||||:||..|..|:..|:|..||
Human   174 -----GYIQNYRCRGDD---SKVQEARKSFFSGHASFSMYTMLYLVLYLQARFTWRGARLLRPLL 230

  Fly   306 QFLLLMFAWYTALTRVSDYKHHWSDVLAGSGIGLTYAVVV 345
            ||.|:|.|:||.|:||||:|||.||||||...|...|..:
Human   231 QFTLIMMAFYTGLSRVSDHKHHPSDVLAGFAQGALVACCI 270

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.