DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wun2 and DPP1

DIOPT Version :9

Sequence 1:	NP_524991.1	Gene:	wun2 / 53558	FlyBaseID:	FBgn0041087	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_010570.1	Gene:	DPP1 / 851878	SGDID:	S000002692	Length:	289	Species:	Saccharomyces cerevisiae

Alignment Length:	264	Identity:	71/264 - (26%)
Similarity:	119/264 - (45%)	Gaps:	56/264 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 LTDLCLLSCVGLPMLGFSL-WGEAVKRGFFCDDSSLRHPYRDS-TMPSWILYLMCGALP-LTVML 153
            |.|:.||  :.:.:|.:.: :.:..:|.|:.:|.::.|||..: .:.:.:|::....:| ||:::
Yeast    19 LEDVFLL--IIMILLNYPVYYQQPFERQFYINDLTISHPYATTERVNNNMLFVYSFVVPSLTILI 81

  Fly   154 VVEFFRGQDKRLHSPFPKSTMCSGYHLCHLELPTWLVECYHRMGIFIFGLGVEQLSTNIAKYSIG 218
            :....  .|:| |..|...|...|..|      .|....:.               ||..|..||
Yeast    82 IGSIL--ADRR-HLIFILYTSLLGLSL------AWFSTSFF---------------TNFIKNWIG 122

  Fly   219 RLRPHFYTLCQPVMKDGTTCSDPINAARYIEEFTCAAVDITS--KQLKDMRLSFPSGHASFACYS 281
            ||||.|...||||  :|.    |::..     ||...|..|.  ::|.|...:.||||:|.:...
Yeast   123 RLRPDFLDRCQPV--EGL----PLDTL-----FTAKDVCTTKNHERLLDGFRTTPSGHSSESFAG 176

  Fly   282 MLYLVIYLHRRM--------QWKQLRMLCHLLQFLLLMFAWYTALTRVSDYKHHWSDVLAGSGIG 338
            :.||..:|..::        .|::      ::.||.|:.|...||:|..||:||:.||:.||.:|
Yeast   177 LGYLYFWLCGQLLTESPLMPLWRK------MVAFLPLLGAALIALSRTQDYRHHFVDVILGSMLG 235

  Fly   339 LTYA 342
            ...|
Yeast   236 YIMA 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	48/162 (30%)
DPP1	NP_010570.1	PAP2_containing_1_like	50..245	CDD:239484	63/231 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2488
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46697
orthoMCL	1	0.900	-	-		OOG6_100228
Panther	1	1.100	-	-	O	PTHR10165
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3374
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.790